Results 41 to 50 of about 91,948 (288)
The Centre-Periphery Dialectics in Eastern Sicily Retail System. An Exploratory Research
This paper aims at scrutinizing from an historical perspective the deep transformations shaped by retail spaces and new consumption patterns challenging long-entrenched dichotomies, such as the centre-periphery one.
Caterina Barilaro +3 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
In this study, a Ti composite reinforced with 5 vol. % (TiBw + TiCp) was fabricated by an in situ casting route. Open die forging in (α + β) phase region was conducted on the composite casting.
Jianchao Han +6 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Eurozone needs exit rules [PDF]
This paper argues that the key issue for defining and solving the Eurozone's (EZ) difficulties lies in readjusting the relationship between the centre and the periphery of the EZ. Our argument proceeds in two steps.
Fahrholz, Christian, Wójcik, Cezary
core
Teoria systemów-światów Immanuela Wallersteina i jej recepcja w archeologii: część III – okres wpływów rzymskich [PDF]
Immanuel Wallerstein’s centre-periphery model lies at the root of many archaeological studies, particularly studies of romanisation. One of them has been an article written by Peter S.
Ciesielska, Adriana
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The article is devoted to analysis of the experience of methodological synthesis, carried out during the reconstruction of the historical evolution of science and higher historical education in Siberia. In relation to the object of study three approaches
Dmitry V. Khaminov
doaj +1 more source

