Results 31 to 40 of about 90,326,780 (286)
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
Newsletter: Centre for Mountain Studies [PDF]
Contents of Newsletter -CMS Mission Statement -CMS Activities -CMS Membership -Natural hazard modelling -Economic analysis of possum control in National Parks -Ecological evaluation of Mt John grasslands -Reform of Pastoral Land Tenure -Caucasian Clover:
Centre for Mountain Studies
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Centre For Graduate Studies: Graduate Programmes: 2001 2002/ Centre for Graduate Studies, UiTM [PDF]
The Centre for Graduate Studies, established in April 1997, is aimed at providing opportunities for Bumiputera graduates to further their education at master's and doctoral levels.
UiTM, Centre for Graduate Studies
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Center for Land Tenure Studies 2022 Annual Report
The Centre for Land Tenure Studies (CLTS) published in 11 working papers and 14 peer reviewed journal articles. The published worked covered issues around land tenure policies, land markets, housing markets, environmental reliance, and REDD ...
Norwegian University of Life Sciences (NMBU) - Centre for Land Tenure Studies (CLTS)
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Anatomy of b → c τ ν anomalies
In recent times, one of the strongest hints of Physics Beyond the Standard Model (BSM) has been the anomaly in the ratios R D and R D * $$ {R}_{D^{*}} $$ measured in the charged current decays of B-mesons.
Aleksandr Azatov +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

