Results 31 to 40 of about 225,991 (262)

Anatomy of b → c τ ν anomalies

Journal of High Energy Physics, 2018
In recent times, one of the strongest hints of Physics Beyond the Standard Model (BSM) has been the anomaly in the ratios R D and R D * $$ {R}_{D^{*}} $$ measured in the charged current decays of B-mesons.
Aleksandr Azatov, Debjyoti Bardhan, Diptimoy Ghosh, Francesco Sgarlata, Elena Venturini   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Asymptotic freedom in the Hamiltonian approach to binding of color

EPJ Web of Conferences, 2017
We derive asymptotic freedom and the SU(3) Yang-Mills β-function using the renormalization group procedure for effective particles. In this procedure, the concept of effective particles of size s is introduced. Effective particles in the Fock space build
Gómez-Rocha María
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

“C.H.A.M.P. Families”: Description and Theoretical Foundations of a Paediatric Overweight and Obesity Intervention Targeting Parents—A Single-Centre Non-Randomised Feasibility Study [PDF]

International Journal of Environmental Research and Public Health, 2018
Childhood obesity represents a significant global health challenge, and treatment interventions are needed. The purpose of this paper is to describe the components and theoretical model that was used in the development and implementation of a unique parent-focussed paediatric overweight/obesity intervention. C.H.A.M.P.
Kristen C. Reilly, Patricia Tucker, Jennifer D. Irwin, Andrew M. Johnson, Erin S. Pearson, Dirk E. Bock, Shauna M. Burke   +6 more
openaire   +4 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Leading soft theorem for multiple gravitini

Journal of High Energy Physics, 2019
We compute leading soft theorem for multiple gravitini (and gravitons) in an arbitrary theory of supergravity with an arbitrary number of finite energy particles by extending Sen’s approach [1, 2] to fermionic symmetry. Our results are independent of the
Diksha Jain, Arnab Rudra
doaj   +1 more source

Neumann–Rosochatius system for (m,n) string in $$AdS_3 \times S^3$$ A d S 3 × S 3 with mixed flux

European Physical Journal C: Particles and Fields, 2021
$$SL(2,{\mathbb {Z}})$$ S L ( 2 , Z ) invariant action for probe (m, n) string in $$AdS_3\times S^3\times T^4$$ A d S 3 × S 3 × T 4 with mixed three-form fluxes can be described by an integrable deformation of an one-dimensional Neumann–Rosochatius (NR ...
Adrita Chakraborty, Kamal L. Panigrahi
doaj   +1 more source

Information and communication technology enabling partnership in person-centred diabetes management: building a theoretical framework from an inductive case study in The Netherlands [PDF]

BMJ Open, 2019
ObjectivesThe aim of this paper is to construct a theoretical framework for information and communication technology (ICT)-enabled partnership towards diabetes management.DesignWe conducted an inductive case study and held interviews on the development and use of an artificial pancreas (AP) system for diabetes management.SettingThe study was carried ...
Sabine E Wildevuur, Lianne WL Simonse, Peter Groenewegen, Ab Klink   +3 more
openaire   +5 more sources