Results 91 to 100 of about 3,262 (203)

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source

Advanced modelling and visualisation of liquid-liquid separations of complex sample components, with variable phase distribution and mode of operation

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research is about liquid-liquid chromatography modelling.
De Folter, Jozefus Johannes Martinus
core  

Extraction of Nonionic Surfactants from Waste Water Using Centrifugal Partition Chromatography

, 1992
A novel method for the extraction of nonionic surfactants from waste water is described which uses centrifugal partition chromatography (CPC). The extractant is the liquid stationary phase of the CPC apparatus, and the raffinate serves as the mobile ...
Bertrand, Gary L., Menges, Randy A., Armstrong, Daniel W., Spino, Larry A., Menyes, T. S.   +4 more
core   +1 more source

Effects of Elevated CO2 on Bean Pod Mottle Virus Infection in Both Incompatible and Compatible Interactions With Phaseolus vulgaris L

Plant, Cell &Environment, Volume 49, Issue 7, Page 4493-4512, July 2026.
ABSTRACT Plant viruses cause significant crop losses, a situation that could worsen due to anthropogenic activities driving global climate change, one factor of which is the increase in atmospheric CO2 concentration. This study assessed the impact of elevated CO2 concentration (eCO2, 1000 vs. 400 ppm) on two genotypes of common bean (Phaseolus vulgaris
Tiffanie Scandolera, Julie Lintz, Ariane Gratias, Ellea Aboud, Simon Rochoux, Maria V. Préjean, Gilles Chatel Innocenti, Marie Garmier, Gianluca Teano, Juan C. Alvarez‐Diaz, Graham Noctor, Valérie Geffroy, Stéphanie Pflieger   +12 more
wiley   +1 more source

Monoclonal antibody (mAb) purification by counter current chromatography (CCC)

, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Counter current chromatography (CCC) is a form of liquid liquid chromatography, which the Brunel Institute for Bioengineering (BIB) team have developed to ...
Fernando, Samantha
core  

Submerged Fermentation of the Edible Mushroom Pleurotus ostreatus in a Batch Stirred Tank Bioreactor as a Promising Alternative for the Effective Production of Bioactive Metabolites

Molecules, 2012
The aim of this study was to investigate the potential of the submerged fermentation procedure in the production of bioactive metabolites of the common edible mushroom Pleurotus ostreatus.
Nikolas Fokialakis, Alexandros-Leandros Skaltsounis, Paul Christakopoulos, Evangelos Topakas, Lefki-Maria Papaspyridi, Nektarios Aligiannis   +5 more
doaj   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, Volume 38, Issue 34, 17 June 2026.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Enantioseparation using a counter-current bioreactor

, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The potential of countercurrent chromatography (CCC) as a small footprint bioreactor/separator for manufacture of enantiopure chiral molecules was explored,
Grudzien, Lukasz
core  

Salt‐Driven Silk Fibroin Assembly for Solvent‐Free Multienzyme Co‐Immobilization

ChemCatChem, Volume 18, Issue 12, 26 June 2026.
Salt‐induced silk fibroin assembly enables solvent‐free co‐immobilization of redox enzyme cascades in fully aqueous media without covalent modification. The protein matrix provides high operational stability and modulates cofactor accessibility, enhancing functional coupling within the confined microenvironment.
Juan Cruz Almada, Miguel Marco‐Martín, Uriel A. Ruiz‐Castillo, Susana Velasco‐Lozano   +3 more
wiley   +1 more source

Centrifugal Partition Chromatography. V. Octanol-water Partition Coefficients, Direct And Indirect Determination

, 1988
Octanol-water partition coefficients (Koct) are one of the accepted physico-chemical parameters for predicting the biological effects of organic chemicals.
Il Han, Yoon, Berthod, Alain, Armstrong, Daniel W.   +2 more
core   +1 more source