Results 101 to 110 of about 3,262 (203)
Critical role of keratinocytes and protease‐activated receptor 2 in secondary lymphedema development
Activated keratinocytes play an important role in the early stage of the pathophysiology of secondary lymphedema through PAR2 signaling. Lymphatic injury‐induced protease activation stimulates keratinocyte PAR2 signaling, driving hyperkeratosis and Th2 inflammation, which can be therapeutically attenuated by teriflunomide. Abstract Background Secondary
Hyeung Ju Park +18 more
wiley +1 more source
ABSTRACT Extracellular vesicles (EVs) are central mediators of tumour‐stroma communication, yet the mechanisms governing their biogenesis and functional cargo remain poorly understood. Here, we identify CD133 (Prominin‐1), selectively expressed in basal‐like triple‐negative breast cancer (BL‐TNBC) cells, acts as a key organizer of EV production and ...
Mireia Gomez‐Duro +14 more
wiley +1 more source
Salix daphnoides: A Screening for Oligomeric and Polymeric Proanthocyanidins
In the present study, a qualitative analysis of proanthocyanidins (PAs) from an aqueous-methanolic extract of Salix daphnoides VILL. bark is described. Procyanidin B1 (1), B2 (2), B3 (3), B4 (4), C1 (5), epicatechin-(4β→8)-epicatechin-(4β→8)-catechin (6)
Stefan Wiesneth +2 more
doaj +1 more source
Centrifugal partition chromatography in the separation of ecdysteroids [PDF]
openaire +1 more source
Abstract The pathological expansion of the polyglutamine (polyQ) repeat within the first exon of huntingtin (Httex1) protein is a defining hallmark of Huntington's disease (HD). Multiple evidence supports that the membrane recruitment of Httex1 is critical for its self‐assembly and related toxicity in HD.
Tânia Sousa +6 more
wiley +1 more source
Preparative separation of quinolines by centrifugal partition chromatography with gradient elution
Centrifugal partition chromatography has been successfully applied to the separation of 2-alkylquinolines from liquid combinatorial synthesis crude samples. Original gradient elution using the ternary two-phase solvent systems heptane-water-acetonitrile and heptane-acetonitrile-methanol were used to separate them with high purity degrees.
Duret, P. +6 more
openaire +3 more sources
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen +11 more
wiley +1 more source
Abstract Ship emissions from high sulfur residual fuel oil (RFO) are a major source of air pollution in coastal and marine environments. Emissions include sulfur oxides as well as fine particulate matter (PM2.5) enriched in vanadium (V) and nickel (Ni).
Francesca Gallo +15 more
wiley +1 more source
International audienceWhen apples are processed into juices or ciders, a great variety of neoformed molecules are generated by enzymatic oxidation of polyphenols.
Castillo Fraire, Claudia Mariana +4 more
core +1 more source
Separation and purification of xylose oligomers using centrifugal partition chromatography
Xylose oligomers, which have a prebiotic effect, have been used as additives to human and animal food. These oligomers are also the primary intermediate in hemicellulose degradation during the pretreatment of biomass. Centrifugal partition chromatography (CPC) was used in this study to separate and purify xylan-derived oligomers from birchwood xylan ...
Ching-Shuan, Lau +6 more
openaire +2 more sources

