Results 261 to 270 of about 59,497 (285)
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Yeast, 1987
Significant progress has been made toward understanding the roles played by conserved centromere DNA sequences in both mitotic and meiotic chromosome segregation. We are just beginning to formulate a picture of what a yeast kinetochore actually looks like and what components other than CEN DNA are necessary for function.
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Significant progress has been made toward understanding the roles played by conserved centromere DNA sequences in both mitotic and meiotic chromosome segregation. We are just beginning to formulate a picture of what a yeast kinetochore actually looks like and what components other than CEN DNA are necessary for function.
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Current Opinion in Genetics & Development, 2007
At the foundation of all eukaryotic kinetochores is a unique histone variant, known as CenH3 (centromere histone H3). We are starting to identify the histone chaperones responsible for CenH3 deposition at centromere DNA, and the mechanisms that restrict CenH3 from chromosome arms.
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At the foundation of all eukaryotic kinetochores is a unique histone variant, known as CenH3 (centromere histone H3). We are starting to identify the histone chaperones responsible for CenH3 deposition at centromere DNA, and the mechanisms that restrict CenH3 from chromosome arms.
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Nature, 2002
Centromeric DNA repeats can be thought of as selfish elements that constantly compete to beat the odds and make it into the egg at meiosis.
Steven, Henikoff, Harmit S, Malik
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Centromeric DNA repeats can be thought of as selfish elements that constantly compete to beat the odds and make it into the egg at meiosis.
Steven, Henikoff, Harmit S, Malik
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Centromere spreading and centromeric aberrations in ovarian tumors
Cancer Genetics and Cytogenetics, 1995Centromere spreading (CS) of chromosomes and high occurrence of aberrations at centromeric region were observed in two papillary serous cystadenocarcinomas and one borderline papillary serous cystadenoma of the ovary. In the borderline tumor, CS of chromosome 12, trisomy of which had been reported as the sole abnomaly in benign ovarian tumors, was seen
D, Zhu, M S, Ma, R Z, Zhao, M Y, Li
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Human Genetics, 1997
Human centromeres have been extensively studied over the past two decades. Consequently, more is known of centromere structure and organization in humans than in any other higher eukaryote species. Recent advances in the construction of a human (or mammalian) artificial chromosome have fostered increased interest in determining the structure and ...
C, Lee +4 more
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Human centromeres have been extensively studied over the past two decades. Consequently, more is known of centromere structure and organization in humans than in any other higher eukaryote species. Recent advances in the construction of a human (or mammalian) artificial chromosome have fostered increased interest in determining the structure and ...
C, Lee +4 more
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Sister chromatid exchange in the centromere and centromeric area
Human Genetics, 1983Central and peripheral sister chromatid exchanges (SCE) were evaluated separately in human phytohemagglutinin (PHA)-stimulated lymphocytes after culture for 72 h in 5-bromodeoxyuridine (BrdU) containing medium. At the same time, the length of chromosome No.
R, Becher, A A, Sandberg
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Centromere Silencing Mechanisms
2017Centromere function is essential for genome stability and chromosome inheritance. Typically, each chromosome has a single locus that consistently serves as the site of centromere formation and kinetochore assembly. Decades of research have defined the DNA sequence and protein components of functional centromeres, and the interdependencies of specific ...
Shannon M, McNulty, Beth A, Sullivan
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