Results 261 to 270 of about 88,605 (330)

Regulation of pericentromeric DNA loop size via Scc2-cohesin interaction. [PDF]

iScience
Nguyen SA, Sakata T, Shirahige K, Sutani T.   +3 more
europepmc   +1 more source

The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells

FASEB BioAdvances, Volume 7, Issue 6, June 2025.
The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia, Slimane Ait‐Si‐Ali, Fabien Le Grand   +2 more
wiley   +1 more source

Efficacy and Safety of Rituximab in Connective Tissue Disease‐Associated Thrombotic Thrombocytopenic Purpura/Thrombotic Microangiopathy

International Journal of Rheumatic Diseases, Volume 28, Issue 6, June 2025.
ABSTRACT Introduction This study examined the efficacy and safety of Rituximab (RTX) treatment in connective tissue disease (CTD)‐associated thrombocytopenic purpura (TTP) and thrombotic microangiopathy (TMA), using historical controls as comparators.
Naoaki Ohkubo, Shingo Nakayamada, Shunsuke Fukuyo, Yusuke Miyazaki, Yoshino Inoue, Hiroaki Tanaka, Yasuyuki Todoroki, Yoshiya Tanaka   +7 more
wiley   +1 more source

The functional organisation of the centromere and kinetochore during meiosis. [PDF]

Curr Opin Cell Biol
Koch LB, Marston AL.
europepmc   +1 more source

An Auxin Inducible Degradation System to Study Mklp2 Functions in MDCK Epithelial Cells

Biology of the Cell, Volume 117, Issue 6, June 2025.
This manuscript details the generation of an MDCK cell line in which the kinesin Mklp2 (KIF20A) is targeted at the endogenous level with an auxin inducible degradation (AID) tag and a GFP tag. This new tool facilitates the study of Mklp2 endogenous localization and constitutes a highly specific system for exploring Mklp2 functions at different stages ...
Morgane Rodriguez, Valérie Simon, Bénédicte Delaval, Benjamin Vitre   +3 more
wiley   +1 more source

Differing Genetics of Saline and Cocaine Self‐Administration in the Hybrid Mouse Diversity Panel

Genes, Brain and Behavior, Volume 24, Issue 3, June 2025.
Longitudinal genome scans for saline intravenous self‐administration over 10 days in the hybrid mouse diversity panel. ABSTRACT To identify genes that regulate the response to the potentially addictive drug cocaine, we performed a control experiment using genome‐wide association studies (GWASs) and RNA‐Seq of a panel of inbred and recombinant inbred ...
Arshad H. Khan, Jared R. Bagley, Nathan LaPierre, Carlos Gonzalez‐Figueroa, Tadeo C. Spencer, Mudra Choudhury, Xinshu Xiao, Eleazar Eskin, James D. Jentsch, Desmond J. Smith   +9 more
wiley   +1 more source

Cattle T2T X Chromosome: Insights into Natural Neocentromere Evolution

Low W, Pineda P, Macphillamy C, Ren Y, Chen T, Zhong L, Adelson D, Dessaix C, Perez-Silva J, Haggerty L, Martin F, Bottema C, Pitchford W, Rosen B, Smith T.   +14 more
europepmc   +1 more source

Recent updates of centromere proteins in hepatocellular carcinoma: a review. [PDF]

Infect Agent Cancer
Yang Z, Chen W, Liu Y, Niu Y.
europepmc   +1 more source

The Use of Optical Genome Mapping for the Detection of Tyrosine Kinase Gene Fusions in Myeloid/Lymphoid Neoplasms

Journal of Cellular and Molecular Medicine, Volume 29, Issue 12, June 2025.
ABSTRACT Myeloid/Lymphoid Neoplasms with eosinophilia and involvement of Tyrosine Kinase gene fusions (MLN‐TK) is a WHO disease category including a diverse group of malignancies characterised by recurrent genomic rearrangements of tyrosine kinase (TK) genes such as PDGFRA, PDGFRB, FGFR1, JAK2, ETV6 and FLT3.
Justine Vanhevel, Katrina Rack, Geneviève Ameye, Hayat Mokrani, Jolien De Bie, Lucienne Michaux, Barbara Dewaele   +6 more
wiley   +1 more source

Genome assembly of the maize B chromosome provides insight into its epigenetic characteristics and effects on the host genome. [PDF]

Genome Biol
Liu Q, Liu Y, Yi C, Gao Z, Zhang Z, Zhu C, Birchler JA, Han F.   +7 more
europepmc   +1 more source