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The mutational dynamics of the Arabidopsis centromeres

open access: yes
Dong X   +7 more
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Architecture and Function of Holocentric CENP-A-Independent Kinetochores

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Yu C   +14 more
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Chromatin Protection by the Chromosomal Passenger Complex

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Gireesh A   +13 more
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Emerging roles of centromeric RNAs in centromere formation and function

Genes & Genomics, 2021
Centromeres are specialized chromosomal domains involved in kinetochore formation and faithful chromosome segregation. Despite a high level of functional conservation, centromeres are not identified by DNA sequences, but by epigenetic means. Universally, centromeres are typically formed on highly repetitive DNA, which were previously considered to be ...
Yang Liu   +7 more
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Centromeric retrotransposons and centromere function

Current Opinion in Genetics & Development, 2018
The centromeric DNA of most multicellular eukaryotes consists of tandem repeats (TR) that bind centromere-specific proteins and act as a substrate for the efficient repair of frequent double-stranded DNA breaks. Some retrotransposons target active centromeres during integration with such specificity that they can be used to deduce current and historic ...
openaire   +3 more sources

Centromerization

Trends in Cell Biology, 2000
Centromere formation is a complex process that involves the packaging of DNA into a centromere-unique chromatin, chemical modification and the seeding of kinetochore and associated proteins. The early steps in this process, in which a chromosomal region is marked for centromerization (that is, to become resolutely committed to centromere formation ...
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Centromere spreading and centromeric aberrations in ovarian tumors

Cancer Genetics and Cytogenetics, 1995
Centromere spreading (CS) of chromosomes and high occurrence of aberrations at centromeric region were observed in two papillary serous cystadenocarcinomas and one borderline papillary serous cystadenoma of the ovary. In the borderline tumor, CS of chromosome 12, trisomy of which had been reported as the sole abnomaly in benign ovarian tumors, was seen
Mei S. Ma   +3 more
openaire   +3 more sources

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