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An mTOR-Stat3-Stathmin pathway controls centrosome and microtubule dynamics for oocyte polarization.
Shawahny A +3 more
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Centrosome Softening As A Mechanical Adaptation For Mitosis
Garcia-Baucells J +9 more
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Centrosome instability: when good centrosomes go bad
Cellular and Molecular Life Sciences, 2021The centrosome is a tiny cytoplasmic organelle that organizes and constructs massive molecular machines to coordinate diverse cellular processes. Due to its many roles during both interphase and mitosis, maintaining centrosome homeostasis is essential to normal health and development. Centrosome instability, divergence from normal centrosome number and
John M. Ryniawec, Gregory C. Rogers
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Centrosomal and non‐centrosomal microtubules
Biology of the Cell, 1999While microtubule (MT) arrays in cells are often focused at the centrosome, a variety of cell types contain a substantial number of non‐centrosomal MTs. Epithelial cells, neurons, and muscle cells all contain arrays of non‐centrosomal MTs that are critical for these cells' specialized functions. There are several routes by which non‐centrosomal MTs can
T J, Keating, G G, Borisy
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Centrosome biogenesis and function: centrosomics brings new understanding
Nature Reviews Molecular Cell Biology, 2007Centrosomes, which were first described in the late 19th century, are found in most animal cells and undergo duplication once every cell cycle so that their number remains stable, like the genetic material of a cell. However, their function and regulation have remained elusive and controversial. Only recently has some understanding of these fundamental
Monica Bettencourt-Dias, David M Glover
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