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Centrosome Softening As A Mechanical Adaptation For Mitosis

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Garcia-Baucells J   +9 more
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Centrosome instability: when good centrosomes go bad

Cellular and Molecular Life Sciences, 2021
The centrosome is a tiny cytoplasmic organelle that organizes and constructs massive molecular machines to coordinate diverse cellular processes. Due to its many roles during both interphase and mitosis, maintaining centrosome homeostasis is essential to normal health and development. Centrosome instability, divergence from normal centrosome number and
John M. Ryniawec, Gregory C. Rogers
openaire   +2 more sources

Centrosomal and non‐centrosomal microtubules

Biology of the Cell, 1999
While microtubule (MT) arrays in cells are often focused at the centrosome, a variety of cell types contain a substantial number of non‐centrosomal MTs. Epithelial cells, neurons, and muscle cells all contain arrays of non‐centrosomal MTs that are critical for these cells' specialized functions. There are several routes by which non‐centrosomal MTs can
T J, Keating, G G, Borisy
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Centrosome biogenesis and function: centrosomics brings new understanding

Nature Reviews Molecular Cell Biology, 2007
Centrosomes, which were first described in the late 19th century, are found in most animal cells and undergo duplication once every cell cycle so that their number remains stable, like the genetic material of a cell. However, their function and regulation have remained elusive and controversial. Only recently has some understanding of these fundamental
Monica Bettencourt-Dias, David M Glover
exaly   +3 more sources

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