Cepacia Syndrome in a Non-Cystic Fibrosis Patient [PDF]
Case Reports in Infectious Diseases, 2015 Burkholderia (formerly Pseudomonas) cepacia complex is a known serious threat to patients with cystic fibrosis, in whom it has the potential to cause the fatal combination of necrotizing pneumonia, worsening respiratory failure, and bacteremia, known as ...
Naomi Hauser, Jose Orsini
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Right lung agenesis with multi-drug-resistant Cepacia syndrome: A case report [PDF]
Journal of Family Medicine and Primary CareLung agenesis (LA) is a rare congenital anomaly that refers to an absence of lung tissue and bronchi. Burkholderia cepacia complex (BCC) causes a fatal acute necrotising pneumonia called Cepacia syndrome.
Mohit Kondisetti +4 more
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Cepacia-Like Syndrome Caused by Burkholderia mutivorans [PDF]
Canadian Journal of Infectious Diseases, 2003 The variable severity of Burkholderia cepacia complex infections in cystic fibrosis (CF) has recently been ascribed to differences in the virulence between genomovars.
George Zahariadis +2 more
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Proteomic profiling of Burkholderia cenocepacia clonal isolates with different virulence potential retrieved from a cystic fibrosis patient during chronic lung infection. [PDF]
PLoS ONE, 2013 Respiratory infections with Burkholderia cepacia complex (Bcc) bacteria in cystic fibrosis (CF) are associated with a worse prognosis and increased risk of death. In this work, we assessed the virulence potential of three B.
Andreia Madeira +7 more
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Management of Cepacia syndrome in an immunocompetent non-cystic fibrosis adult patient
International Journal of Infectious Diseases, 2022 Burkholderia cepacia complex (BCC) is nonfermenting, Gram-negative bacteria known to cause high morbidity and mortality. They commonly affect patients with cystic fibrosis (CF) and are often missed in those without, despite being fatal if left untreated.
Niyas Khalid Ottu Para +10 more
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Management of Cepacia Syndrome With a Combination of Intravenous and Inhaled Antimicrobials in a Non-Cystic Fibrosis Pediatric Patient. [PDF]
J Pediatr Pharmacol Ther, 2020 Burkholderia cepacia complex (Bcc) is an opportunistic pathogen, posing little risk to healthy individuals. The presentation of Bcc can vary from a virtually asymptomatic chronic infection, to an acute, life-threatening necrotizing pneumonia, acute respiratory distress syndrome, and bacteremia (cepacia syndrome) associated with a mortality ...
Branstetter JW, Yarbrough A, Poole C.
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Macrophage activation syndrome/haemophagocytic lymphohistiocytosis secondary to Burkholderia cepacia complex septicaemia in an elderly female carrier of X-linked chronic granulomatous disease with extreme lyonisation: 'cepacia syndrome' revisited. [PDF]
BMJ Case Rep, 2019 X-linked carriers of chronic granulomatous disease (CGD) may become phenotypically affected if substantial skewing from lyonisation occurs. We describe a 73-year-old female carrier with an overt CGD phenotype due to skewed lyonisation, complicated by macrophage activation syndrome (MAS)/haemophagocytic lymphohistiocytosis (HLH) secondary to ...
Urriola N, Williams A, Keat K.
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A Case Report of Necrotizing Pneumonia Due to Burkholderia cepacia Syndrome. [PDF]
CureusBurkholderia cepacia (B. cepacia) complex is a highly resistant gram-negative pathogen known to cause lung infection in cystic fibrosis, chronic granulomatous disease, and immunocompromised patients. However, it may rarely infect immunocompetent patients as well.
Hedary AS, DeBord NL, Marshall D.
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Saudi Journal of Kidney Diseases and Transplantation, 2022 Burkholderia cepacia is almost always a colonizing organism rather than an infecting organism, but it may be pathogenic in immunocompromised individuals when isolated from body fluids that are ordinarily sterile.
Vijoy Kumar Jha +3 more
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The Small RNA ncS35 Regulates Growth in
mSphere, 2018 Burkholderia cenocepacia J2315 is a member of the B. cepacia complex. It has a large genome with three replicons and one plasmid; 7,261 genes code for annotated proteins, while 113 code for functional RNAs. Small regulatory RNAs of B.
Sanne Kiekens +4 more
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