Results 101 to 110 of about 2,260,600 (191)
Abstract Background Cystic fibrosis (CF) is a genetic disease that causes progressive lung disease with major impact on the quality of life. Lung ultrasound (LUS) allows to assess the lung involvement through the artefacts analysis and is increasingly used in children but is not yet used to monitor people with CF(pwCF).
Antonietta Curatola +6 more
wiley +1 more source
THE MICROBIOTA OF LOWER AIRWAYS IN PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASES
Aim. We aimed to estimate the composition and the detection frequency of bacterial species in induced sputum samples from patients with bronchial asthma (BA), chronic obstructive lung disease (COPD) and its combined phenotype (ACOS).
S. A. Mazurina +6 more
doaj +1 more source
Functional neutrophil disorders: Chronic granulomatous disease and beyond
Summary Since their description by Metchnikoff in 1905, phagocytes have been increasingly recognized to be the entities that traffic to sites of infection and inflammation, engulf and kill infecting organisms, and clear out apoptotic debris all the while making antigens available and accessible to the lymphoid organs for future use.
Christa S. Zerbe, Steven M. Holland
wiley +1 more source
Early-Onset Autoimmune Disease as a Manifestation of Primary Immunodeficiency [PDF]
Autoimmune disorders (AID) have been increasingly observed in association with primary immunodeficiencies (PIDs). Here, we discuss the interface between PID and AID, focusing on autoimmune manifestations early in life, which can be diagnostic clues for ...
Carneiro-Sampaio, Magda +1 more
core +2 more sources
Gut microbes as medical signature for the effectiveness of immunotherapy in patients with advanced non‐small cell lung cancer. Abstract Lung cancer (LC) is the most common cause of cancer‐related death worldwide and poses a severe threat to public health.
Adane Adugna +5 more
wiley +1 more source
A Burkholderia cenocepacia infection usually leads to reduced survival and fatal cepacia syndrome in cystic fibrosis patients. The identification of B. cenocepacia essential genes for in vivo survival is key to designing new anti-infectives therapies. We
Yee-Chin Wong +7 more
doaj +1 more source
Regulatory small RNAs play an essential role in maintaining cell homeostasis in bacteria in response to environmental stresses such as iron starvation.
Andrea M Sass, Tom Coenye
doaj +1 more source
First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2004. ©The Trustee of the Wellcome Trust, London, 2004. All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/Annotated ...
Christie, DA, Tansey, EM
core
Transcriptomic analysis of longitudinal Burkholderia pseudomallei infecting the cystic fibrosis lung [PDF]
The melioidosis bacterium, Burkholderia pseudomallei, is increasingly being recognised as a pathogen in patients with cystic fibrosis (CF). We have recently catalogued genome-wide variation of paired, isogenic B.
Bell, Scott C. +5 more
core +1 more source
The mechanism of action of auranofin analogs in B. cenocepacia revealed by chemogenomic profiling
Drug repurposing efforts led to the discovery of bactericidal activity in auranofin, a gold-containing drug used to treat rheumatoid arthritis. Auranofin kills Gram-positive bacteria by inhibiting thioredoxin reductase, an enzyme that scavenges reactive ...
Dustin T. Maydaniuk +10 more
doaj +1 more source

