Results 71 to 80 of about 2,260,600 (191)

Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms [PDF]

, 2019
Combining antibiotics with potentiators that increase their activity is a promising strategy to tackle infections caused by antibiotic-resistant bacteria.
Abatih, Emmanuel, Bové, Mona, Buroni, Silvia, Chiarelli, Laurent R, Coenye, Tom, Crabbé, Aurélie, Ostyn, Lisa, Sass, Andrea, Slachmuylders, Lisa, Van Acker, Heleen, Van Nieuwerburgh, Filip, Vandenbussche, Ian   +11 more
core   +2 more sources

Structure of O-Antigen and Hybrid Biosynthetic Locus in Burkholderia cenocepacia Clonal Variants Recovered from a Cystic Fibrosis Patient

Frontiers in Microbiology, 2017
Burkholderia cenocepacia is an opportunistic pathogen associated with chronic lung infections and increased risk of death in patients with cystic fibrosis (CF).
A.A. Hassan, Rita F. Maldonado, Sandra C. dos Santos, Flaviana Di Lorenzo, Alba Silipo, Carla P. Coutinho, Vaughn S. Cooper, Antonio Molinaro, Miguel A. Valvano, Isabel Sá-Correia   +9 more
doaj   +1 more source

Blinatumomab Along With Combined Antifungal Agents for Refractory Adult Acute Lymphoblastic Leukemia With Invasive Aspergillosis: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT There is an increased risk of invasive aspergillosis (IA) during the induction of acute lymphoblastic leukemia (ALL) because of the use of cytoreductive chemotherapy and high‐dose steroids. This case demonstrates the utility of metagenomic next‐generation sequencing and repeat sampling in clarifying complex infections and highlights ...
Yutong Liu, Fan Xia, Wenzhi Cai, Ying Zhang, Jiawei Zhu, Zhen Shen, Jiaxin Li, Qiannan Yang, Qi Qu, Jia Chen   +9 more
wiley   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima, Al-Herz, Waleed, Bousfiha, Aziz, Casanova, Jean-Laurent, Chatila, Talal, Cunningham-Rundles, Charlotte, Etzioni, Amos, Franco, Jose Luis, Holland, Steven M, Jeddane, Leila, Klein, Christoph, Morio, Tomohiro, Ochs, Hans D, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Sullivan, Kathleen E, Tangye, Stuart G, Torgerson, Troy R   +18 more
core  

Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)

Veterinary Dermatology, Volume 36, Issue 3, Page 234-282, June 2025.
Background – Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives – To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler, Christine L. Cain, Lluís Ferrer, Koji Nishifuji, Katarina Varjonen, Mark G. Papich, Luca Guardabassi, Siân M. Frosini, Emi N. Barker, J. Scott Weese   +9 more
wiley   +1 more source

Research Progress on the Epidemiology, Clinical Characteristics, and Resistance Mechanisms of Burkholderia Cepacia Complex

Xiehe Yixue Zazhi
The Burkholderia cepacia complex (Bcc) comprises a group of genetically related yet phenotypically diverse Gram-negative opportunistic pathogens. These organisms demonstrate significant pathogenicity in immunocompromised populations, particularly cystic ...
CUI Wenjie, LU Rongqi, LIU Yali
doaj   +1 more source

What matters in chronic Burkholderia cenocepacia infection in cystic fibrosis: Insights from comparative genomics. [PDF]

PLoS Pathogens, 2017
Burkholderia cenocepacia causes severe pulmonary infections in cystic fibrosis (CF) patients. Since the bacterium is virtually untreatable by antibiotics, chronic infections persist for years and might develop into fatal septic pneumonia (cepacia ...
Jaroslav Nunvar, Vaclav Capek, Karel Fiser, Libor Fila, Pavel Drevinek   +4 more
doaj   +1 more source

Identification of Burkholderia spp. in the clinical microbiology laboratory: comparison of conventional and molecular methods [PDF]

, 1999
Cystic fibrosis (CF) predisposes patients to bacterial colonization and infection of the lower airways. Several species belonging to the genus Burkholderia are potential CF-related pathogens, but microbiological ...
Belkum, A.F. (Alex) van, Goessens, W.H.F. (Wil), Pelt, C. (Cindy) van, Reubsaet, F., Segonds, C., Tummler, B., Verbrugh, H.A. (Henri), Verduin, C.M. (Cees), Vos, M.C. (Margreet)   +8 more
core  

Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]

, 2016
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA, DUSE, MARZIA, Laitano, Rossella, LEONARDI, LUCIA   +3 more
core   +1 more source