For series 2a–d, there appears to be optimal activity against Klebsiella pneumoniae when lipophilicity is intermediate (log P 2.64 for 2b). Similarly, for series 2e–g, activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus mutans also increases (log P 3.71 for 2f).
Agenor P. Luz‐Filho +9 more
wiley +1 more source
Determination of worst-case cephalosporin residues in laboratory glassware using a validated low-level RP-HPLC method. [PDF]
Althobaiti SA +4 more
europepmc +1 more source
Postoperative Takotsubo Cardiomyopathy in a Young Woman: A Case Report
Timeline of the patient's clinical course. ABSTRACT Takotsubo cardiomyopathy (TCM) can occur in young adults exposed to extreme physical stress, such as surgery, sepsis, and transfusion reactions. Mechanical recovery may precede electrical normalization, with ECG abnormalities persisting despite improved left ventricular ejection fraction (LVEF). Early
Nadia Siddiq +6 more
wiley +1 more source
Clonal Expansion of <i>penA</i>-60.001 in Cephalosporin-Resistant <i>Neisseria gonorrhoeae</i>: A Molecular Epidemiology Study in Meizhou, China, 2020-2024. [PDF]
Li Q +5 more
europepmc +1 more source
Stability of Novel Siderophore Cephalosporin S-649266 against Clinically Relevant Carbapenemases
Tsukasa Ito-Horiyama +9 more
semanticscholar +1 more source
ABSTRACT Late‐onset neonatal meningitis due to Serratia marcescens is an uncommon but potentially life‐threatening healthcare‐associated infection in NICUs. We report a sporadic case in a preterm infant who developed fever on Day 17 of life after a prolonged hospital stay for feeding difficulties and neonatal jaundice.
Bunngeth Seng +2 more
wiley +1 more source
Changes in the Gut Microbiome Following Perioperative Prophylactic Cefazolin Administration in Patients Undergoing Orthopedic Surgery: A Longitudinal Prospective Study. [PDF]
Kim D +8 more
europepmc +1 more source
ABSTRACT Background and Aims β‐lactam antibiotics stand as the most profoundly impactful classes of antibacterial agents worldwide. Their widespread application has raised safety concerns over adverse events (AEs), such as blood and lymphatic system disorders (BLSDs).
Jing Liu +6 more
wiley +1 more source
Rapid Intrauterine Fetal Death Caused by <i>Listeria monocytogenes</i> in Mid-Pregnancy: A Case Report and Literature Review. [PDF]
Sun W, Liu J, Sun H, Cui X.
europepmc +1 more source
ABSTRACT Background Sepsis disrupts intestinal microbiota, and broad‐spectrum antibiotics may worsen dysbiosis. Clostridioides difficile (C. difficile) infection (CDI) is a prevalent nosocomial enteric pathogen among critically ill patients, yet its prognostic implications in sepsis remain inadequately studied.
Jiyun Hu +6 more
wiley +1 more source

