Results 201 to 210 of about 104,609 (288)

Controlled Delivery and Light‐Induced Release of Magic Spot Nucleotides in Escherichia coli

Angewandte Chemie International Edition, Volume 65, Issue 15, 6 April 2026.
We synthesized photocaged, clickable and isotope‐labeled “magic spot” Nucleotides and delivered them into Escherichia coli comparing different approaches. Light‐controlled release inside living cells enabled tracking of their conversion from pppGpp to ppGpp by capillary electrophoresis mass spectrometry and revealed their impact on the growth rate of a
Christoph Popp, Patrick Moser, Anselm Schwoerbel, Xinwei Liu, Johannes Freitag, Pinku Sarmah, Isabel Prucker, Robert Zscherp, Xuan Wang, Philipp Klahn, Hans‐Georg Koch, Gert Bange, Henning J. Jessen   +12 more
wiley   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Antibiotic Prescribing for Cellulitis in the Absence of Penicillin-Cephalosporin Cross-Reactivity Alerts: A Retrospective Study. [PDF]

Pharmacol Res Perspect
Sundermann M, Mehrtens JAH, Douglas NM, Gardiner SJ, Doogue M, Chin PKL.   +5 more
europepmc   +1 more source

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

Advanced Science, Volume 13, Issue 22, 17 April 2026.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu   +10 more
wiley   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

Systematic review of antimicrobial pharmacokinetic/pharmacodynamic indices in murine thigh and hollow fibre dose fractionation studies analysed with a standard method. [PDF]

J Antimicrob Chemother
Alabdulkarim N, Readman J, Mead A, Oakley R, Wenker S, Kembou J, Azzariti S, Bajaj-Elliott M, Cortina-Borja M, Standing JF.   +9 more
europepmc   +1 more source

An Unusual Case of Citrobacter koseri Infection During Pregnancy at 27 Weeks: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Early prenatal screening at 26 + 6 weeks detected Citrobacter koseri vaginal colonization in an asymptomatic high‐risk gravida. Culture‐guided IV ceftazidime (susceptible per CLSI testing) eradicated the pathogen without maternal/fetal compromise.
Mario Assenza, Michele Caramia, Jacopo Wabersich   +2 more
wiley   +1 more source

Correction: Molecular resistance mechanisms to newly approved antibiotics (2017-2025) in WHO priority pathogens. [PDF]

Front Microbiol
Frontiers Production Office.
europepmc   +1 more source

Destructive Erysipelothrix rhusiopathiae Endocarditis Confirmed on Valve Tissue Culture After Persistent Blood Culture Negativity

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Echocardiographic evidence of Erysipelothrix rhusiopathiae infective endocarditis. ABSTRACT Erysipelothrix rhusiopathiae is a zoonotic, gram‐positive bacillus that is a virulent cause of infective endocarditis (IE) and incurs a high mortality rate. Its virulence is compounded by intrinsic resistance to common empirical agents including vancomycin and ...
Mahdid Azam, Abbey Isaac, Hashim Azam, Raja Chinthamuneedi, Robert Horvath   +4 more
wiley   +1 more source

Antibiotic Prophylaxis Strategies and Surgical Site Infections in Colorectal Surgery: A Systematic Review and Network Meta-Analysis.

JAMA Netw Open
Motaghi S, Karam SG, Mulazzani F, Mirzayeh Fashami F, Buchan TA, Ibrahim S, Moradi Falah Langeroodi S, Khademioore S, Couban RJ, Mbuagbaw L, Mertz D, Loeb M.   +11 more
europepmc   +1 more source