Effect of non-cephalosporin antibiotic prophylaxis on the risk of periprosthetic joint infection after total joint replacement surgery: a retrospective study with a 1-year follow-up [PDF]
Infection Prevention in Practice, 2023 Summary: Background: Cephalosporins are recommended as first-line antibiotic prophylaxis in total joint replacement surgery. Studies have shown an increased risk for periprosthetic joint infection (PJI) when non-cephalosporin antibiotics have been used.
Meeri Honkanen +4 more
doaj +2 more sources
Cefuroxime - a new cephalosporin antibiotic.
The Journal of Antibiotics, 1976 Cefuroxime is a new broad spectrum cephalosporin antibiotic for administration by injection. It is stable to most beta-lactamases. It is active against gram-positive organisms, including penicillinase-producing staphylococci, and has wide activity against gram-negative bacilli including Enterobacter and many strains of indole-positive Proteus spp.
C. O'callaghan +4 more
semanticscholar +6 more sources
In-Silico discovery of novel cephalosporin antibiotic conformers via ligand-based pharmacophore modelling and de novo molecular design [PDF]
Journal of Genetic Engineering and BiotechnologyAntibiotic resistance poses a significant global challenge as bacteria evolve in response to antibiotic use, leading to prolonged hospitalizations, increased healthcare costs, and higher mortality rates. Cephalosporins, a class of beta-lactam antibiotics,
Rayhan Chowdhury +7 more
doaj +2 more sources
Second generation cephalosporin antibiotic prophylaxis and Clostridium difficile infection in hip and knee arthroplasty. [PDF]
Ann R Coll Surg Engl, 2017 Al-Tawil K +3 more
europepmc +2 more sources
Antibacterial Activity of Cefamandole, a New Cephalosporin Antibiotic, Compared with that of Cephaloridine, Cephalothin, and Cephalexin [PDF]
Antimicrobial Agents and Chemotherapy, 1973 S. Eykyn +3 more
semanticscholar +2 more sources
Cephalexin: human studies of absorption and excretion of a new cephalosporin antibiotic
British Journal of Pharmacology, 1969 P. Gower, C. Dash
semanticscholar +2 more sources
Implementation of an intensified antibiotic stewardship programme targeting third-generation cephalosporin and fluoroquinolone use in an emergency medicine department [PDF]
Emergency Medicine Journal, 2014 J. Borde +6 more
semanticscholar +2 more sources
In Vitro Activity and Pharmacokinetics in Patients of Cefamandole, a New Cephalosporin Antibiotic
Antimicrobial Agents and Chemotherapy, 1975 N. Shemonsky, J. Carrizosa, M. Levison
semanticscholar +2 more sources
Metabolic Fate of [14C]Cefamandole, a Parenteral Cephalosporin Antibiotic, in Rats and Dogs
Antimicrobial Agents and Chemotherapy, 1977 H. Sullivan +4 more
semanticscholar +2 more sources