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Effect of non-cephalosporin antibiotic prophylaxis on the risk of periprosthetic joint infection after total joint replacement surgery: a retrospective study with a 1-year follow-up [PDF]

open access: yesInfection Prevention in Practice, 2023
Summary: Background: Cephalosporins are recommended as first-line antibiotic prophylaxis in total joint replacement surgery. Studies have shown an increased risk for periprosthetic joint infection (PJI) when non-cephalosporin antibiotics have been used.
Meeri Honkanen   +4 more
doaj   +2 more sources

The guidelines on antibiotic application in gynaecological oncology [PDF]

open access: yesArchive of Oncology, 2005
Standardized and effective antibiotic therapy regimes in gynecology need to be based on the protocols prescribed by acknowledged specialists. Antibiotic therapy can have either prophylactic or therapeutic purposes.
Mladenović-Segedi Ljiljana   +4 more
doaj   +3 more sources

STAPHYLOCOCCUS AUREUS RESISTANCE AGAINST CEPHALOSPORIN ANTIBIOTIC IN ADEN-YEMEN

open access: goldمجلّة جامعة عدن للعلوم الأساسيّة والتّطبيقيّة, 2021
The study was carried out to determine antibacterial resistance profiles of methicillin-resistant Staphylococcus aureus (MRSA), isolated from clinical samples (n: 352) of patients during the period, from January 2019 to July 2020 in five governmental and
Eman Abdo Ali   +2 more
doaj   +3 more sources

Cefuroxime - A new cephalosporin antibiotic.

open access: yesThe Journal of Antibiotics, 1976
Cefuroxime is a new broad spectrum cephalosporin antibiotic for administration by injection. It is stable to most beta-lactamases. It is active against gram-positive organisms, including penicillinase-producing staphylococci, and has wide activity against gram-negative bacilli including Enterobacter and many strains of indole-positive Proteus spp.
C H, O'Callaghan   +4 more
openaire   +4 more sources

In-Silico discovery of novel cephalosporin antibiotic conformers via ligand-based pharmacophore modelling and de novo molecular design [PDF]

open access: yesJournal of Genetic Engineering and Biotechnology
Antibiotic resistance poses a significant global challenge as bacteria evolve in response to antibiotic use, leading to prolonged hospitalizations, increased healthcare costs, and higher mortality rates. Cephalosporins, a class of beta-lactam antibiotics,
Rayhan Chowdhury   +7 more
doaj   +2 more sources

1. Reduced utilization of meropenem post successful implementation of Neonatal Intensive Care Unit empiric sepsis treatment guideline [PDF]

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Neonatal intensive care units (NICU) are associate with a high level of antibiotic consumption. Appropriate antibiotic use is crucial to minimize the emergence of resistance and unintended consequences to the patient.
Laura Sass   +2 more
doaj   +2 more sources

The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria [PDF]

open access: yesNature Reviews Microbiology, 2008
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
Mathias Winterhalter
exaly   +2 more sources

Cost-Effectiveness Analysis of Third-Generation Cephalosporin Antibiotics in the Treatment of Typhoid Fever at Tangerang Selatan General Hospital

open access: diamondIndonesian Journal of Pharmaceutical Education
Typhoid fever is an acute systemic infectious disease caused by Salmonella typhi bacteria that infect through contaminated food or drink. In the treatment of typhoid fever, antibiotic therapy is needed.
Mochammad Widya Pratama   +2 more
doaj   +3 more sources

Antimicrobial stewardship approach in reducing incidence of ESBL cases [PDF]

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: With the increasing cases of multi-resistant organism infection, Antimicrobial Stewardship Programs (ASP) is an important tool in combating this rising challenges. The objective of this study is to review whether the approach of the reduction
Lau Hui Shan   +3 more
doaj   +2 more sources

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