Results 141 to 150 of about 941,736 (352)

Ceftriaxone, an FDA-approved cephalosporin antibiotic, suppresses lung cancer growth by targeting Aurora B.

Carcinogenesis, 2017
Xiang Li, Haitao Li, Shengqing Li, Feng Zhu, Dong Joon Kim, Hua Xie, Yan Li, Janos Nadas, N. Oi, T. Zykova, Dong Hoon Yu, Mee-Hyun Lee, M. Kim, Lei Wang, Weiya Ma, Ronald A. Lubet, A. Bode, Ziming Dong, Zigang Dong   +18 more
semanticscholar   +1 more source

Understanding antimicrobial use by equine owners in Wales: Using cross‐sectional survey and semi‐structured interviews

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is an increasingly serious threat to human and animal health. Antimicrobial use (AMU) in horses is gathering research interest, although there remain significant evidence gaps. Currently, there is scant qualitative research into equine owners' use of antimicrobials, specifically antibiotics, hindering ...
Rebekah B. Stuart, Fleur Miles‐Farrier, Alison M. Bard, Gwen Rees   +3 more
wiley   +1 more source

Effectiveness of Cephalosporins /Siderophore Cephalosporins Versus Meropenem as Therapy in Patients with Hospital Acquired Pneumonia

Journal of Pharmacoeconomics and Pharmaceutical Management
Background: Hospital Acquired Pneumonia (HAP) or nosocomial pneumonia is an infection caused mainly by gram-negative bacteria. Carbapenems and cephalosporins/cephalosporin siderophores are effective for infections caused by gram-negative bacteria ...
Palevi Ruflianasari, Tri Murti Andayani, Dwi Endarti   +2 more
doaj  

Molecular basis of antibiotic sensing by the TetR family regulator CecR – a structural perspective

The FEBS Journal, EarlyView.
Escherichia coli CecR, a member of the TetR family regulators, senses selected antibiotics and activates the expression of a putative drug efflux pump. Although present in many pathogenic Enterobacteriales strains, CecR remains poorly characterized. We present the first CecR crystal structure, which reveals a unique tunnel‐like ligand‐binding cavity ...
Agnieszka J. Pietrzyk‐Brzezinska, Anna Koczurowska, Marta Orlikowska, Maciej Nielipinski, Dominika Nielipinska, Bartosz Sekula   +5 more
wiley   +1 more source

Meropenem‐Heparin Lock Therapy for Ochrobactrum intermedium Catheter‐Related Bloodstream Infection in a Pediatric Hemodialysis Patient: A Case Report and Literature Review

Hemodialysis International, EarlyView.
ABSTRACT Background In pediatric hemodialysis patients with exhausted vascular access, managing rare pathogens like Ochrobactrum intermedium is challenging, often posing a dilemma between catheter removal and salvage attempts. There are few reports on the supported viability of meropenem‐heparin lock therapy for this purpose in pediatric patients. Case
Mônica Cristina Dutra Rodrigues, Fernanda Teixeira Sillva, Anderson Pereira de Oliveira, Yeo Jim Kinoshita Moon, Jhohann Richard de Lima Benzi   +4 more
wiley   +1 more source

Gonorrhea Management in High‐, Limited‐ and No‐Resource Settings: Implications in the Context of Antimicrobial Resistance

International Journal of Dermatology, EarlyView.
ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov, Maciej Pastuszczak, George‐Sorin Tiplica   +2 more
wiley   +1 more source

Gene clusters for β-lactam antibiotics and control of their expression: why have clusters evolved, and from where did they originate? [PDF]

, 2010
While β-lactam compounds were discovered in filamentous fungi, actinomycetes and gram-negative bacteria are also known to produce different types of β-lactams. All β-lactam compounds contain a four-membered β-lactam ring.
Juan F. Martín, Paloma Liras
core   +2 more sources

Time to Hang Up the Gloves: A Scoping Review of Evidence on Non‐Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To systematically summarise evidence related to the use of non‐sterile gloves when preparing and administering intravenous antimicrobials. Design Scoping review. Methods A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta ...
Natasya Raja Azlan, Debbie Massey, Lesley Andrew, Amanda Towell‐Barnard, Seng Giap Marcus Ang, Carol Crevacore, Martina Costello, Aaron Alejandro, Weiting Liu, Naila Zaman, Peta‐Anne Zimmerman   +10 more
wiley   +1 more source

2094. Acceptability of Antibiotic Substitutions for Fluoroquinolones and Third and Fourth-generation Cephalosporins: A Report from the VA-CDC Practice-Based Research Network (PBRN) [PDF]

, 2019
Matthew Bidwell Goetz, Stacey Hockett Sherlock, Cassie Cunningham Goedken, Erin Balkenende, Charlesnika T. Evans, Eli N. Perencevich, Kelly Echevarria, Sujan Reddy, Melinda M. Neuhauser, Heather Schacht Reisinger, Katie J. Suda   +10 more
openalex   +1 more source

Mandatory Preemptive Skin Testing and Its Impact on Penicillin Allergy Labeling Across Different Healthcare Settings in Mainland China and Hong Kong

Allergy, EarlyView.
Weihong Shi, Lanting Wang, Shengan Chen, Philip Hei Li, Xiaoqun Luo   +4 more
wiley   +1 more source