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Increase in the incidence of multidrug-resistant Gram-negative bacterial strains pose a significant threat to healthcare system worldwide. New antibiotics are necessary to combat particularly resitant pathogens.
Karol Lorenc Lorenc+7 more
doaj +3 more sources
The last three decades have seen the emergence of a cornucopia of antimicrobials in the cephalosporin class. This becomes even more apparent when one realizes that over 60 pages of the 1993 AHFS drug information text is dedicated to the cephalosporin class.1 Due to similarities in nomenclature and the proliferation of available agents, the clinician ...
R A, Otto, A D, Noorily
openaire +2 more sources
The state and consideration for skin test of β-lactam antibiotics in pediatrics
β-lactam antibiotics are the most frequently used drugs and the most common drugs that cause allergic reactions in pediatrics. The occurrence of some allergic reactions can be predicted by skin testing, especially severe adverse reactions such as ...
Chunhui Gao+3 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source
Purpose To determine the efficacy and safety of different prophylactic systemic antibiotics in adult and pediatric patients receiving chemotherapy or undergoing hematopoietic stem cell transplantation (HSCT).
Grace Egan+11 more
doaj +1 more source
Opportunities for penicillin allergy evaluation in dental clinics
Objective: To evaluate opportunities for assessing penicillin allergies among patients presenting to dental clinics. Design: Retrospective cross-sectional study. Setting: VA dental clinics.
Amanda Vivo+8 more
doaj +1 more source
In order to utilize the leftover materials from traditional Chinese medicine production and to remove antibiotics from wastewater, extracted herbal residues were used as raw materials to produce activated carbon. To keep a constant quality and adsorption
Suimin Li, Qian Yang, Y. Ye
semanticscholar +1 more source
Nephrotoxicity of cefepime: A new cephalosporin antibiotic in rats
Objectives: To investigate the nephrotoxic effect and biochemical alterations induced by cefepime in rats. Materials and Methods: Cefepime was administered intramuscularly at doses of 45, 90 and 180 mg/kg b.wt. once daily for 5 consecutive days.
M. G. Elsayed+3 more
semanticscholar +1 more source
We conducted a phase I bioequivalence trial in healthy Chinese subjects in the fasting and postprandial states. The goal of this trial was to compare the pharmacokinetics and safety of the test preparation Cefaclor granule (Disha Pharmaceutical Group Co.,
Xinyao Qu+15 more
doaj +1 more source
Reciprocal Regulation of Cephalosporin Resistance in
Antibiotic-resistant enterococci are major causes of hospital-acquired infections and therefore represent a serious public health problem. One well-known risk factor for the acquisition of hospital-acquired enterococcal infections is prior therapy with ...
Christopher J. Kristich+3 more
doaj +1 more source