Results 291 to 300 of about 941,736 (352)
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Mayo Clinic proceedings, 1983
Cephalosporin antibiotics are bactericidal against most gram-positive cocci and gram-negative bacilli of clinical importance. They are relatively nontoxic but like the penicillins may cause hypersensitivity reactions. Agents with clinically advantageous pharmacokinetics include cefazolin, moxalactam, and cefadroxil.
R L, Thompson, A J, Wright
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Cephalosporin antibiotics are bactericidal against most gram-positive cocci and gram-negative bacilli of clinical importance. They are relatively nontoxic but like the penicillins may cause hypersensitivity reactions. Agents with clinically advantageous pharmacokinetics include cefazolin, moxalactam, and cefadroxil.
R L, Thompson, A J, Wright
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The Cephalosporin Antibiotics in Pediatric Practice
Southern Medical Journal, 1977The efficacy of the cephalosporins against gram-positive cocci and some of the gram-negative bacilli together with their relative safety make this family of antibiotics potentially useful in treating pediatric infections, particularly in instances of penicillin hypersensitivity.
S, Ross, W, Rodriguez, W, Khan
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Cephalosporin, Carbapenem, and Monobactam Antibiotics
Mayo Clinic Proceedings, 1987Cephalosporin and related antibiotics are highly effective bactericidal agents of relatively low toxicity. The spectrum of activity varies with the drug but is usually broad. The first-generation cephalosporins, and especially cefazolin, are most active against sensitive staphylococci and streptococci.
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The cephalosporin antibiotics in pediatric therapy
European Journal of Pediatrics, 1986The cephalosporins have been available for clinical use for nearly 20 years and a large number is presently marketed, including drugs with a wide range of different pharmacokinetic and microbiologic properties. While some of these agents have certain specific uses in which they excel, the cephalosporins have not replaced older antibiotics but do ...
H F, Eichenwald, H J, Schmitt
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Extraction and purification of cephalosporin antibiotics
1997The biologically active natural and semisynthetic cephalosporin antibiotics require proper methods of extraction and purification for their isolation and subsequent pharmacological studies. This article reviews the various methods useful for extraction and purification of individual compounds as well as the enzymes involved in their biosynthesis ...
A C, Ghosh, R K, Mathur, N N, Dutta
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Mechanisms of Resistance to Cephalosporin Antibiotics
Drugs, 1987Cephalosporins, like other beta-lactams, bind to the bacterial penicillin-binding proteins (PBPs). These correspond to the D-ala-D-ala trans-, carboxy- and endo-peptidases responsible for catalysing the cross-linking of newly formed peptidoglycan.
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[Mercurimetric determination of cephalosporin antibiotics].
Die Pharmazie, 1988The conditions for a potenciometric estimation of cefuroxime, cefsulodin, cefotaxime and ceftriaxon with mercury(II) perchlorate after the previous reaction of the antibiotics with hydroxylamine were established. The mercurimetric determination was well reproducible with the relative error of the mean ranging up to 1% and the results are identical with
B, Pospísilová, J, Kubes
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Cephalosporins and Related Antibiotics: An Overview
Clinical Infectious Diseases, 1982With the release of cefotaxime and, more recently, moxalactam, there are now 13 cephalosporin drugs available in the United States, and close to another half dozen are under investigation. Commercial competition is steep, and every new product is being praised as superior to its predecessor.
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Third Generation Cephalosporin Antibiotics in Surgical Practice
Journal of Urology, 1986The new third generation cephalosporins have a significantly greater spectrum of action against gram-negative bacteria likely to be encountered in surgical infections. This expanded spectrum may permit these drugs to be used in place of combination therapy in patients with polymicrobial infections; however, current evidence does not indicate superior ...
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CXA-101 - Cephalosporin antibiotic
2010(Chemical Equation Presented) CXA-101 is a novel broad-spectrum cephalosporin active against highly resistant clinical isolates and laboratory strains of Pseudomonas aeruginosa, including isolates resistant to ceftazidime, multidrug-resistant isolates, AmpC-hyperproducing clones and highly resistant cystic fibrosis isolates.
Perletti, G. +3 more
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