Results 311 to 320 of about 149,559 (362)
Some of the next articles are maybe not open access.
Biosynthesis of Cephalosporins
1976Publisher Summary This chapter discusses the biosynthesis of cephalosporins. A variety of cephalosporins and their producers has been found, however it has not been conclusively determined what the secondary metabolites are in a strict sense of the term.
Toshihiko Kanzaki, Yukio Fujisawa
openaire +3 more sources
Classification of Cephalosporins
Drugs, 1987Many cephalosporins are now in clinical use. They have a wide range of activity against different species of bacteria and also differ in their pharmacokinetic and metabolic characteristics. This article outlines a basis for comparison and classification of cephalosporins into 4 groups active mainly against: (1) Gram-positive bacteria; (2) Gram-negative
openaire +3 more sources
Continuous deacetylation of cephalosporins
Biotechnology and Bioengineering, 1980AbstractContinuous deacetylation of cephalosporin C, 7‐aminocephalosporanic acid, and of 2‐methoxyethyl acetate in packed beds of an immobilized esterase is described by simple empirical equations relating conversion to space velocity and temperature.
J. Konecny, Meinrad Sieber
openaire +3 more sources
Immunology and Allergy Clinics of North America, 2004
Allergic reactions to cephalosporins may occur because of sensitization to cephalosporin determinants shared with penicillin or to unique cephalosporin haptens. The exact nature of the haptenic determinants resulting from the degradation of currently available cephalosporins is incompletely understood.
Arvind, Madaan, James T-C, Li
openaire +2 more sources
Allergic reactions to cephalosporins may occur because of sensitization to cephalosporin determinants shared with penicillin or to unique cephalosporin haptens. The exact nature of the haptenic determinants resulting from the degradation of currently available cephalosporins is incompletely understood.
Arvind, Madaan, James T-C, Li
openaire +2 more sources
Chemical Research in Toxicology, 2011
Cephalosporins, after penicillins, are the most widely used antibacterial agents in infectious diseases and the cause of adverse immune reactions in the world.
Maria Isabel Montannez +5 more
semanticscholar +1 more source
Cephalosporins, after penicillins, are the most widely used antibacterial agents in infectious diseases and the cause of adverse immune reactions in the world.
Maria Isabel Montannez +5 more
semanticscholar +1 more source
Pediatrics In Review, 1998
The cephalosporins are the largest and most diverse family of antimicrobial agents available. Although they rarely are considered drugs of first choice for the therapy of bacterial infections, they are the most commonly prescribed agents for both ambulatory and hospitalized patients.
openaire +2 more sources
The cephalosporins are the largest and most diverse family of antimicrobial agents available. Although they rarely are considered drugs of first choice for the therapy of bacterial infections, they are the most commonly prescribed agents for both ambulatory and hospitalized patients.
openaire +2 more sources
Journal of Medicinal Chemistry, 1977
The acidic aqueous degradation of the 7alpha-aminophenylglycinamido-containing cephalosporin cephalexin (1a) has been examined. Two major degradation products have been isolated and characterized: 3-formyl-3,6-dihydro-6-phenyl-2.5(1H,4H)-pyrazinedione (5) and 3-hydroxy-4-methyl-2(5H)-thiophenone (6).
openaire +2 more sources
The acidic aqueous degradation of the 7alpha-aminophenylglycinamido-containing cephalosporin cephalexin (1a) has been examined. Two major degradation products have been isolated and characterized: 3-formyl-3,6-dihydro-6-phenyl-2.5(1H,4H)-pyrazinedione (5) and 3-hydroxy-4-methyl-2(5H)-thiophenone (6).
openaire +2 more sources