Results 171 to 180 of about 110,293 (352)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

Gut bacteroides thetaiotaomicron-deriven ceramides promote perivascular adipose tissue-endothelial senescence in aging [PDF]

open access: bronze
Khatereh Shabanian   +10 more
openalex   +1 more source

Skin Barrier Biomarkers in Patch‐Induced and Clinical Allergic and Irritant Contact Dermatitis

open access: yesContact Dermatitis, EarlyView.
Both patch‐induced and clinical ICD and ACD showed consistent alterations in skin barrier‐associated biomarkers, indicative of skin barrier impairment. Among the tested allergens, chromium elicited more pronounced biomarker responses compared to nickel and methylisothiazolinone.
Sanja Kezic   +8 more
wiley   +1 more source

The Role of Sphingolipid Metabolism and Neuron Death in Ischemic Stroke: A New Perspective from Bioinformatics. [PDF]

open access: yesBrain Behav
First, we evaluated of differences in sphingolipid metabolism using peripheral blood samples from IS patients and healthy controls. Then, we identify the hub genes linking sphingolipid metabolism and neuronal death via modular analysis of protein‐protein interaction networks.
Chen ZC   +8 more
europepmc   +2 more sources

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

open access: yesCell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu   +5 more
wiley   +1 more source

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