The Role of Ceramides in Metabolic and Cardiovascular Diseases. [PDF]
Gonzalez-Plascencia M +3 more
europepmc +1 more source
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer +11 more
wiley +1 more source
Differential effects of PCSK9 inhibitors and statins on plasma ceramides in coronary artery disease. [PDF]
Zhang L, Ding Y, Zeng Y.
europepmc +1 more source
On why cancer cells require a great amount of glucose
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu +6 more
wiley +1 more source
Ceramide as a key regulatory factor in the impact of dietary inflammatory index on plaque stability. [PDF]
Zhao Z +12 more
europepmc +1 more source
Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico +9 more
wiley +1 more source
ANP-ing Up Diabetes: Impaired Natriuretic Peptide Action in Muscle Forms a Mechanistic Link Between Obesity and Diabetes [PDF]
Cleasby, M E
core +2 more sources
Ceramide-based machine learning models for the diagnosis of unstable angina: a prospective multicenter study. [PDF]
Xie Z +12 more
europepmc +1 more source
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
Efficacy Evaluation of N-Acyl-Phytosphingosine Prepared from Marula Oil Derived Fatty Acids in Skin Barrier Repair. [PDF]
Liu Z, Zhu H, Yang Y, Chang H.
europepmc +1 more source

