Results 41 to 50 of about 67,929 (292)
Fluorescent annexin A1 reveals dynamics of ceramide platforms in living cells [PDF]
, 2008 Upon its genesis during apoptosis, ceramide promotes gross reorganization of the plasma membrane structure involving clustering of signalling molecules and an amplification of vesicle formation, fusion and trafficking.
Katia Monastyrskaya +5 more
core +1 more source
Developmental Comparison of Ceramide in Wild-Type and Cln3Δex7/8 Mouse Brains and Sera
Frontiers in Neurology, 2019 CLN3 disease is a neurodevelopmental disease leading to early visual failure, motor decline, and death. CLN3 pathogenesis has been linked to dysregulation of ceramide, a key intracellular messenger impacting various biological functions.
Sally El-Sitt +6 more
doaj +1 more source
Separation of neutral glycosphingolipids and sulfatides by thin-layer chromatography
Journal of Lipid Research, 1967 Two one-dimensional systems for separation of glycolipids from total lipid extracts of tissues by thin-layer chromatography are described. System I used, as adsorbent, an alkaline mixture of silica gel without CaSO4 binder (75%) and magnesium silicate ...
Vladimir P. Skipski +2 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Studies about radiation damage in vivo are very significant for healthy risk assessment as well as cancer radiotherapy. Ceramide as a second messenger has been found to be related to radiation-induced apoptosis. However, the detailed mechanisms in living
Yaning Yang +6 more
doaj +1 more source
Ceramide in Plasma Membrane Repair [PDF]
, 2013 The perforation of the plasmalemma by pore-forming toxins causes an influx of Ca2+ and an efflux of cytoplasmic proteins. In order to ensure cellular survival, lesions have to be identified, plugged and removed from the membrane.
Babiychuk, Eduard B. +3 more
core +1 more source
Characterization of neutral sphingolipids from chicken erythrocytes.
Journal of Lipid Research, 1985 The neutral sphingolipids from chicken erythrocytes were characterized. The total concentration of neutral sphingolipids was found to be 480 nmol/g of dry stroma.
T Shiraishi, Y Uda
doaj +1 more source
A simple, highly sensitive, and facile method to quantify ceramide at the plasma membrane
Journal of Lipid Research, 2023 The role of ceramide in biological functions is typically based on the elevation of cellular ceramide, measured by LC-MS in the total cell lysate. However, it has become increasingly appreciated that ceramide in different subcellular organelles regulates
Meaghan Greene +4 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Plasma ceramide profile. [PDF]
, 2016 Plasma ceramide species were measured by LC/ESI/MS/MS analysis. (A) Ceramide profiles are shown as a heat map similar to above. Ceramide concentrations were log-transformed prior to computing z-scores.
Atif A. Khan (3159315) +15 more
core +1 more source
Cell Reports, 2021 Summary: We lack a mechanistic understanding of aging-mediated changes in mitochondrial bioenergetics and lipid metabolism that affect T cell function.
Silvia Vaena +14 more
doaj +1 more source