Results 161 to 170 of about 338,348 (241)
British Journal of Pharmacology, Volume 183, Issue 12, Page 3173-3194, June 2026.Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová +12 more
wiley +1 more source
Generation of a ceramide synthase 6 mouse lacking the DDRSDIE C-terminal motif. [PDF]
PLoS One, 2022 Kim J +4 more
europepmc +1 more source
Ceramide Synthase-dependent Ceramide Generation and Programmed Cell Death [PDF]
Journal of Biological Chemistry, 2011 Thomas D. Mullen +5 more
openaire +1 more source
Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan +2 more
wiley +1 more source
, 2001 Fumonisin B1 is a mycotoxin produced by fungi of the genus Fusarium, common pathogens of corn and other grain plants. Toxic effects associated with fumonisin B1 include equine leukoencephalomacia, porcine pulmonary edema, rat renal carcinoma, and murine ...
Melchior, W. B., Jr. +6 more
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Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation. [PDF]
Mol Metab, 2023 Jeon S +14 more
europepmc +1 more source
Septins in the Middle—Makers and Breakers of Membrane Contact Sites
Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 6, Page 4121-4135, June 2026.ABSTRACT Cassava (Manihot esculenta Crantz) exhibits exceptional tolerance to infertile soils and contains abundant cyanogenic glucosides (CGs). Previous research has indicated that CGs can serve as a significant reservoir of organic nitrogen in plants.
Weitao Mai +10 more
wiley +1 more source
ORM Expression Alters Sphingolipid Homeostasis and Differentially Affects Ceramide Synthase Activity
, 2016 Sphingolipid synthesis is tightly regulated in eukaryotes. This regulation in plants ensures sufficient sphingolipids to support growth while limiting the accumulation of sphingolipid metabolites that induce programmed cell death.
Chen, Ming +10 more
core
Physiological Reports, Volume 14, Issue 12, June 2026.Abstract Increases in body mass are associated with the development of metabolic dysfunction‐associated steatotic liver disease (MASLD). Caloric restriction (CR) is the primary non‐pharmacological defense against MASLD; however, poor CR maintenance induces partial body mass regain (PR), leading to MASLD progression.
Eira E. Jardines +5 more
wiley +1 more source