Results 151 to 160 of about 338,348 (241)

Role of Ceramide Synthase 1 in Oral Leukoplakia and Oral Squamous Cell Carcinoma: A Potential Linchpin for Tumorigenesis. [PDF]

Cureus, 2023
Surendran S, Poothakulath Krishnan R, Ramani P, Ramalingam K, Jayaraman S.   +4 more
europepmc   +1 more source

Acid ceramidase overactivity drives ceramide loss, leading to atopic dry skin and Th2‐skewed immune polarization

The Journal of Pathology, Volume 269, Issue 2, Page 232-247, June 2026.
Abstract Ceramide deficiency in the stratum corneum (SC) is a key etiological factor in atopic dermatitis (AD). To clarify the direct role of SC ceramide depletion in impairing SC barrier and water‐holding functions and in initiating AD‐like skin symptoms and disease‐specific molecular alterations, we generated Tg mice overexpressing a mutant form of ...
Mariko Takada, Miho Sashikawa‐Kimura, Yusuke Ohno, Md Razib Hossain, Xiaonan Xie, Kazuhisa Iwabuchi, Mayumi Komine, Mamitaro Ohtsuki, Genji Imokawa   +8 more
wiley   +1 more source

Neuronal Prosurvival Role of Ceramide Synthase 2 by Olidogendrocyte-to-Neuron Extracellular Vesicle Transfer. [PDF]

Int J Mol Sci, 2023
Casadomé-Perales Á, Naya S, Fernández-Martínez E, Mille BG, Guerrero-Valero M, Peinado H, Guix FX, Dotti CG, Palomer E.   +8 more
europepmc   +1 more source

SIRT3 Deacetylates Ceramide Synthases [PDF]

Journal of Biological Chemistry, 2016
Sergei A. Novgorodov, Christopher L. Riley, Jarryd A. Keffler, Jin Yu, Mark S. Kindy, Wendy B. Macklin, David B. Lombard, Tatyana I. Gudz   +7 more
openaire   +1 more source

Single‐nucleotide polymorphisms in coronary artery disease: Biological complexity, risk architecture, and implications for precision prevention

Precision Medical Sciences, Volume 15, Issue 2, Page 91-101, June 2026.
This graphical summary highlights the clinical application of single‐nucleotide polymorphisms‐based risk stratification in coronary artery disease. By integrating polygenic risk with clinical assessment, imaging, and preventive strategies, genetic information enables earlier risk identification, optimized screening, and personalized lifestyle and ...
Li Dai, Mosi Chen, Jun Hu, Lei Huang, Ye Yang, Chang Chen, Ying Zhuang, Yan Pan, Bingjun Qian   +8 more
wiley   +1 more source

Sex Differences in Sphingosine-1-Phosphate Levels Are Dependent on Ceramide Synthase 1 and Ceramidase in Lung Physiology and Tumor Conditions. [PDF]

Int J Mol Sci, 2023
Terlizzi M, Colarusso C, Ferraro G, Falanga A, Monti MC, Somma P, De Rosa I, Panico L, Pinto A, Sorrentino R.   +9 more
europepmc   +1 more source

Characterization of Ceramide Synthase 2 [PDF]

Journal of Biological Chemistry, 2008
Elad L. Laviad, Lee Albee, Irene Pankova-Kholmyansky, Sharon Epstein, Hyejung Park, Alfred H. Merrill, Anthony H. Futerman   +6 more
openaire   +1 more source

Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe‐Host‐Interaction With the Most Complex Human Commensal, Demodex folliculorum

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller, S. Walch, S. Gschwendtner, A. Klingl, L. E. French, M. Flaig, B. M. Clanner‐Engelshofen   +6 more
wiley   +1 more source

Biophysical studies of lipid membranes by solid state NMR and molecular dynamics simulations

, 2013
Biological membranes separate the cell interior from the outside and have diverse functions from signal transduction, apoptosis to transportations of ions and small molecules in and out of the cell.
Dutagaci, Bercem
core  

High expression of ceramide synthase 5 predicts a poor prognosis in gastric cancer. [PDF]

Transl Cancer Res, 2022
Zhang S, Wang Y, Yuan L, Hu C, Xu Z, Cheng X.   +5 more
europepmc   +1 more source