Results 31 to 40 of about 151,620 (307)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Effects of Adding Pre Gelatinized Lotus Root Powder on the Quality of Mantou and Its Glycemic Index

open access: yesLiang you shipin ke-ji
In this study, pre gelatinized lotus root powder was added to wheat flour at the proportions of 10%, 20%, 30% and 40%, respectively.The pasting properties and rheological properties of the mixed flour, the quality indicators, in vitro digestion ...
LI Xiao-yue   +7 more
doaj   +1 more source

Genotype by Environment Interaction on Tropical Maize Hybrids Under Normal Irrigation and Waterlogging Conditions

open access: yesFrontiers in Sustainable Food Systems, 2022
Unpredictable rainfall in the tropics often increases the risk of waterlogging or even flooding in agricultural lands, hindering the efforts to fulfill maize demands. Breeding maize for waterlogging tolerance is necessary yet challenging since performing
Muhammad Azrai   +11 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Effect of elevated atmospheric CO2 level on the abiotic and biotic stress tolerance of cereals [PDF]

open access: yes, 2013
Effect of elevated CO2 level (EC) was studied on the tolerance of cereals to elevated temperature and drought and on the resistance of wheat to fungal diseases. In general, elevated growth temperature did not affect final grain size, thus having less
Janda, Tibor   +4 more
core   +1 more source

Design, Development, and Field Validation of a Low-Cost Gsm-Based Early Warning System for Environmental Stress and Disease Detection in Small-Scale Broiler Production Systems in Nigeria: Case study of Minna Municipal, Niger state [PDF]

open access: yesJournal of Agriculture and Rural Development Studies
High mortality rates caused by environmental stress and infectious diseases remain a major constraint to small-scale broiler production in sub-Saharan Africa.
Abubakar Ahmadu Ndakogarba   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

STUDIES ON GENETIC VARIABILITY AND TRAIT RELATIONSHIP IN CASTOR (RICINUS COMMUNIS L.) [PDF]

open access: yesJournal of Plant Development, 2019
Castor oil plant (Ricinus communis L.) is one of highly treasured industrial oil crop around the world. In the present study, genetic variability and trait relationships in some castor genotypes were examined to generate information for castor breeding ...
Kasim Alhassan ALHAJI   +3 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

Sunflower breeding for resistance to the new races of broomrape (Orobanche cumana Wallr.) in Romania

open access: yesPlant Protection Science, 2002
The actual spectrum of the broomrape races in Romania has changed. The study of the sunflower differential set for the broomrape races, under natural and artificial infestation demonstrated the existence of a new spectrum of these races.
M. Păcureanu Joiţa   +2 more
doaj   +1 more source

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