The Effect of Different Forms of Synaptic Plasticity on Pattern Recognition in the Cerebellar Cortex [PDF]
, 2009 “The original publication is available at www.springerlink.com”. Copyright Springer.Many cerebellar learning theories assume that long-term depression (LTD) of synapses between parallel fibres (PFs) and Purkinje cells (PCs) provides the basis for pattern
Adams, R.G. +4 more
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A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Cortical Models for Movement Control [PDF]
, 2000 Defense Advanced Research Projects Agency and Office of Naval Research (N0014-95-l-0409)
Bullock, Daniel
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Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction [PDF]
, 2018 The brain communicates with the spinal cord through numerous axon tracts that arise from discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination of descending commands.
Blackmore, Murray G. +4 more
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SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Comparative evaluation of cerebellum development between Japanese quail and albino rats [PDF]
Journal of Medical and Life ScienceThe surrounding environmental conditions are affected the cerebellum development among different vertebrates. In this study, we attempt to evaluate the differences in cerebellar histogenesis between Japanese quail and albino rats (post-hatching postnatal
Enas Sohsah +4 more
doaj +1 more source
Adaptive Neural Models of Queuing and Timing in Fluent Action [PDF]
, 2003 Temporal structure in skilled, fluent action exists at several nested levels. At the largest scale considered here, short sequences of actions that are planned collectively in prefrontal cortex appear to be queued for performance by a cyclic competitive ...
Bullock, Daniel
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Spinocerebellar Ataxia Type 2 [PDF]
, 2012 1. Introduction: The autosomal dominant cerebellar ataxias (ADCA) are a clinically, pathologically and genetically heterogeneous group of neurodegenerative disorders caused by degeneration of cerebellum and its afferent and efferent connections.
Auburger, Georg +3 more
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[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Neural Dynamics of Learning and Performance of Fixed Sequences: Latency Pattern Reorganizations and the N-STREAMS Model [PDF]
, 2002 Fixed sequences performed from memory play a key role in human cultural behavior, especially in music and in rapid communication through speaking, handwriting, and typing.
Bullock, Daniel, Rhodes, Bradley
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