Results 91 to 100 of about 182,686 (297)

Calcineurin controls the expression of numerous genes in cerebellar granule cells [PDF]

, 2003
The Ca(2+)/calmodulin-dependent phosphatase calcineurin plays a crucial role in gene expression in different cell types such as T-lymphocytes, cardiac myocytes, and smooth muscle cells.
Fresu, Luigia, Ashby, Dominique S, Freeman, Tom C, Genazzani, Armando A, Kramer, Dana   +4 more
core  

AI‐Based Mitochondrial Network Characterization as a Biomarker for DNM1L‐Related Disease Diagnosis

Advanced Intelligent Systems, EarlyView.
This work provides proof‐of‐concept that AI‐based analysis of mitochondrial network morphology in patient‐derived fibroblasts can identify a phenotypic signature associated with DNM1L deficiency. This automated approach may ultimately provide a complementary functional readout for the interpretation of novel DNM1L variants following genetic testing ...
Uliana Musokhranova, Ioannis Georvasilis, Sofía Illescas, Matina Saritzoglou, Marcos Frías, Mònica Roldán, Anna Ardissone, Isabella Moroni, Àngels García‐Cazorla, Alfonso Oyarzábal   +9 more
wiley   +1 more source

Biosensor measurement of purine release from cerebellar cultures and slices [PDF]

, 2010
We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Eason, Robert, Robert Eason, Dale, Nicholas, Wall, Mark J., Mark Wall, Nicholas Dale   +5 more
core   +1 more source

Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis

Annals of Neurology, EarlyView.
Objective As leptomeningeal metastasis (LM) has a poor prognosis, reliable cerebrospinal fluid (CSF) diagnostic biomarkers are urgently needed. This study evaluated the diagnostic value of CSF growth differentiation factor 15 (GDF15) in LM from lung adenocarcinoma (LUAD) and breast cancer (BC).
Haoyu Ruan, Jie Li, Fuhai Wang, Lei Zhang, Jie Luo, Yuan Mu, Ting Wang, Yuqing Wu, Jingping Liu, Yunyun Ning, Xuan Deng, Ming Guan, Jian Xu   +12 more
wiley   +1 more source

Cerebellar sequencing for cognitive processing

, 2013
The idea that cerebellar processing is required in a variety of cognitive functions is well accepted in the neuroscience community. Nevertheless, the definition of the cerebellar role in the different cognitive domains remains obscure.
Maria G. Leggio, Marco Molinari, LEGGIO, Maria   +2 more
core   +1 more source

Production of 3D printed biomodels of the canine brain for veterinary neuroanatomy teaching

Anatomical Sciences Education, EarlyView.
Abstract Teaching neuroanatomy presents multiple challenges to both students and teachers, as it is a subject with highly dense content that commonly causes the development of aversion by students, a phenomenon referred to as “neurophobia,” which has been documented in human and veterinary medicine students.
João Victor Barbosa Tenório Fireman, Antônio Chaves de Assis Neto   +1 more
wiley   +1 more source

Mucinous Neoplasms

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
D'ONOFRIO, Mirko, Paolo Tinazzi Martini, Giovanni Morana, Crosara, Stefano, Riccardo De Robertis, Emilio Barbi, Capelli, Paola, MORANA, Giovanni, Paola Capelli, DE ROBERTIS LOMBARDI, Riccardo, Barbi, Emilio, TINAZZI MARTINI, Paolo, LUCHINI, Claudio, Mirko D’Onofrio, Claudio Luchini, Stefano Crosara   +15 more
core   +1 more source

Cerebral neoplasm in L-2-hydroxyglutaric aciduria: Two different presentations

, 2020
Background: L-2-hydroxyglutaric aciduria (L2HGA) is a rare neurometabolic disorder characterized by a slowly progressive clinical course, psychomotor and mental retardation, macrocephaly, dysarthria, seizures, and cerebellar and extrapyramidal findings ...
Ero?lu, Nilgün, Şahin, Sevim, Aydın, Kürşad, Dilber, Beril, Havalı, Cengiz, Cansu, Ali, Eroglu, Nilgün   +6 more
core   +1 more source

“Hands‐On” white matter anatomy: Using Air Anatomy gestures and tractography on simple brain sections to enhance teaching of white matter directions

Anatomical Sciences Education, EarlyView.
Abstract Teaching white matter (WM) anatomy to undergraduates is challenging. This is partly because WM fibers are oriented intricately and Klingler's dissection, the gold standard method used to demonstrate it, often requires time, advanced anatomical knowledge, and refined dissection skills.
Doris George Yohannan, Rohini Punja, Thomas Iype, Chandrasekharan Kesavadas, Bejoy Thomas, Kannanvilakom Govindapillai Umesan, Aswathy Maria Oommen, Usha Devi Keezhathil Bhargavi   +7 more
wiley   +1 more source

Epidemiology and clinical outcomes of von Hippel-Lindau disease in Korea: a nationwide cohort study

Scientific Reports
von Hippel-Lindau (VHL) disease is a rare tumor syndrome involving neoplasms in multiple organs. Despite extensive research in Western countries, large-scale studies in East Asia remain limited.
Seung Woo Choi, Sang-Jun Shin, Kwangsic Joo, Sangchul Lee, Se Hyun Kim, Sang Jun Park, Jeongwoo Lee, Se Joon Woo   +7 more
doaj   +1 more source