Results 81 to 90 of about 624,789 (324)

High rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglioma-like leptomeningeal neoplasms (DOLN)

Acta Neuropathologica, 2015
Disseminated oligodendroglioma-like leptomeningeal neoplasm (DOLN) is a recently described entity that predominantly affects children, is slowly progressive, and exhibits little, if any, parenchymal involvement.
F. Rodriguez, M. Schniederjan, T. Nicolaides, T. Tihan, P. Burger, A. Perry   +5 more
semanticscholar   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source

Anti-Yo–associated paraneoplastic cerebellar degeneration revealing appendiceal adenocarcinoma: a case report with complete neurological recovery [PDF]

Journal of Neurocritical Care
Background Paraneoplastic cerebellar degeneration (PCD) is a rare immune-mediated disorder often linked to gynecologic or breast tumors, with anti-Yo antibodies being a key marker.
Ümitcan Ateş
doaj   +1 more source

Can magnetic resonance imaging predict preoperative consistency and vascularity of intracranial meningioma?

The Egyptian Journal of Radiology and Nuclear Medicine, 2022
Background Meningiomas are considered the most common primary intracranial neoplasms. The surgical resection is the main curative therapy. Evaluation of meningioma consistency and vascularity is important before surgery to be aware about the difficulties
Ahmed A. ElBeheiry, Ahmed A. Fayed, Ahmed H. Alkassas, Doaa M. Emara   +3 more
doaj   +1 more source

Severity and Progression Rate of Cerebellar Ataxia in 16q-linked Autosomal Dominant Cerebellar Ataxia (16q-ADCA) in the Endemic Nagano Area of Japan [PDF]

, 2009
16q22.1-linked autosomal dominant cerebellar ataxia (16q-ADCA) is a recently defined subtype of ADCA identified by a disease-specific C/T substitution in the 5' untranslated region of the puratrophin-1 gene. In Nagano, the central mountainous district of
Sato, Shunichi, Shimizu, Yusaku, Sakai, Haruya, Okano, Tomomi, Ikeda, Shu-ichi, Hattori, Takeshi, Ohara, Shinji, Tabata, Kenichi, Matsumoto, Naomichi, Inoue, Atsushi, Morita, Hiroshi, Ushiyama, Masao, Nakamura, Katsuya, Tazawa, Ko-ichi, Shimojima, Yasuhiro, Yoshida, Kunihiro, Ohata, Takako   +16 more
core   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Erdheim-Chester disease presenting at the central nervous system

Autopsy and Case Reports, 2021
Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis (LCH) that affects different body systems. It was recently recognized as a neoplastic disorder after identifying an activating mutation of the MAPK pathway. Neurological presentations of
Sydney Fasulo, Mina Fransawy Alkomos, Rovena Pjetergjoka, Erinie M Mekheal, Sharon Awasthi, Sahithi Chittamuri, Vinod Kumar, Mehandar Kumar, Amer Akmal, Michael Maroules   +9 more
doaj  

Ganglioneuroblastoma of the cerebellum: neuroimaging and pathological features of a case Ganglioneuroblastoma no cerebelo: achados de neuroimagem e patologia em um caso

Arquivos de Neuro-Psiquiatria, 2007
OBJECTIVE: To report a case of ganglioneuroblastoma of cerebellum, with emphasis to the neuroimaging and pathological findings. CASE REPORT: A one year and eight-month-old girl presented with a two-month history of hypoactivity and tremor in the legs ...
Emerson L. Gasparetto, Sérgio Rosemberg, Hamilton Matushita, Claudia da Costa Leite   +3 more
doaj   +1 more source

Esophageal Gastrointestinal Stromal Tumor with Rare Intracranial Metastasis

Case Reports in Gastrointestinal Medicine, 2020
Introduction. Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors and constitute the largest group of nonepithelial digestive neoplasms. However, they do not represent more than 1% of primary digestive tumors.
José Carvalho, Margarida Teixeira, Francisco Teixeira Silva, Alexandra Esteves, Carlos Ribeiro, Diana Guerra   +5 more
doaj   +1 more source

Network-based association analysis to infer new disease-gene relationships using large-scale protein interactions. [PDF]

PLoS ONE, 2018
Protein-protein interactions integrated with disease-gene associations represent important information for revealing protein functions under disease conditions to improve the prevention, diagnosis, and treatment of complex diseases.
Apichat Suratanee, Kitiporn Plaimas
doaj   +1 more source