Results 81 to 90 of about 31,920 (298)
Advanced Science, EarlyView.PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Analytic study of clinical presentation of intracranial space-occupying lesions in adult patients [PDF]
, 2014 Intracranial space-occupying lesions can be caused by a variety of disease processes, ranging from neoplasms to non-neoplastic lesions including hematomas, abscesses and vascular malformations.
Alvi, Shafaq +2 more
core +1 more source
Advanced Science, EarlyView.This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley +1 more source
Target cells of human adenovirus type 12 in subtentorial brain tissue of newborn mice. I. Cyto-histomorphologic and immunofluorescent microscopic studies In vivo [PDF]
, 1976 Human adenovirus type 12 (Ad 12) was inoculated through subtentorial route into inbred newborn mice (C3H/BifB/Ki), and sequential changes of the brain and tumor induction were examined by histological and immunofluorescent methods.
Athanasiou, T +9 more
core +2 more sources
PAPILLARY GLIONEURONAL TUMOR OF THE POSTERIOR FOSSA
Revista Ciencias Biomédicas, 2015 Introduction: the papillary glioneuronal tumor (PGT) is an uncommon disease and it has recent categorization. It has probable origin in the pluripotent stem cells of the subependymal zone that is located mainly around the temporal horns of the lateral
Tuñón-Pitalúa Martha Cecilia +5 more
doaj
Diagnostic challenges in hemangioblastoma: lessons from a rare case presentation
Egyptian Journal of NeurosurgeryBackground Hemangioblastomas are rare, slow-growing benign neoplasms predominantly affecting the central nervous system (CNS). Despite their benign nature, they pose diagnostic challenges due to their diverse clinical manifestations and radiological ...
Jayeshkumar Kanani
doaj +1 more source
An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report
Düzce Tıp Fakültesi DergisiCerebellar ependymomas are rare neoplasms, even more so in elderly patients. In this case report, a 75-year-old male patient admitted with a one-year history of progressive general decline, urinary retention, left-sided weakness, memory loss, and ...
Taşkın Yurtseven +3 more
doaj +1 more source
Malignant glioma after ependymoma: an unusual secondary malignancy [PDF]
, 2012 Purpose : Secondary malignancies (SM) are a known long-‐term problem in children surviving brain tumors. We report on two unusual cases of SM observed after treatment of ependymoma. Case reports : 1.
Tinguely, D.
core
Long-term effect of external beam radiotherapy of optic disc hemangioma in a patient with von hippel-lindau disease [PDF]
, 2011 An 18-year-old woman with a 2-year history of hypertension and headache was diagnosed with noradrenalin-secreting bilateral adrenal pheochromocytomas with paragangliomas in the background of von Hippel-Lindau disease with family histories and a missense ...
Himei, Kengo +6 more
core +1 more source
Advanced Science, EarlyView.This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng +13 more
wiley +1 more source