Results 61 to 70 of about 624,789 (324)

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Cervical medulloblastoma mimicking a nerve sheath tumour in a child: A rare extracranial presentation

Българска неврология
Medulloblastoma is the most common malignant pediatric brain tumor, accounting for nearly 20% of all childhood intracranial neoplasms. It is classified as an embryonal tumor and most commonly arises in the cerebellar vermis or hemispheres of children ...
Jaimin Modh, Arvind Verma, Renish Padshala, Nazar Imam   +3 more
doaj   +1 more source

Rare neoplasms

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
Valentina Ciaravino, CIARAVINO, VALENTINA, Roberto Malagò, MALAGO', Roberto, Roberto Pozzi Mucelli, Capelli, Paola, Paola Capelli, DE ROBERTIS LOMBARDI, Riccardo, PEDICA, Federica, Riccardo De Robertis, Federica Pedica, POZZI MUCELLI, Roberto   +11 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Telovelar approach versus transvermian approach in management of fourth ventricular tumors

Egyptian Journal of Neurosurgery, 2019
Background The relationships of the fourth ventricle to the cerebellar surfaces and the fissures through which the fourth ventricle is approached surgically are among the most complex in the brain.
Khaled Saeed Ebrahim, Ahmed Faisal Toubar   +1 more
doaj   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Aggressive CNS Embryonal Tumours: A Series of Three Cases

Journal of Clinical and Diagnostic Research
Central Nervous System (CNS) embryonal tumours represent a heterogeneous group of aggressive paediatric neoplasms with variable clinical presentations, histopathological features, and outcomes.
Shima Kannadas, Rahila Musthafa
doaj   +1 more source

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Consensus guidelines for the management of posterior fossa tumour for low- and middle-income countries

Journal of the Pakistan Medical Association
The posterior fossa is a limited compartment therefore lesions compressing its structures can result in devastating outcomes. It can cause significant neurological deficit due to mass effect on critical structures and hydrocephalus. Due to the nature of
Hafiza Fatima Aziz, Mohammad Hamza Bajwa, Naureen Mushtaq, Saqib Kamran Bakhshi, Kaynat Siddiqui, Saad Akhtar Khan, Rabeet Tariq, Muhammad Shakir, Mehar Masroor, Fatima Suleman, Pakistan Brain Tumour Consortium: (Authors list at the end of the supplement), Syed Ather Enam   +11 more
doaj   +1 more source

Role of Cerebellar Interpositus Nucleus in the Genesis and Control of Reflex and Conditioned Eyelid Responses [PDF]

, 2004
The role of cerebellar circuits in the acquisition of new motor abilities is still a matter of intensive debate. To establish the contribution of posterior interpositus nucleus (PIN) to the performance and/or acquisition of reflex and classically ...
Jimenez-Diaz, L, Navarro Lopez, JDD, Delgado-Garcia, JM, Gruart, A   +3 more
core