Results 61 to 70 of about 182,686 (297)

The role of thioredoxin reductases in brain development [PDF]

, 2008
The thioredoxin-dependent system is an essential regulator of cellular redox balance. Since oxidative stress has been linked with neurodegenerative disease, we studied the roles of thioredoxin reductases in brain using mice with nervous system (NS ...
Jonna Soerensen, Schmidt, Jörg, Soerensen, Jonna, Markus Brielmeier, Schweizer, Ulrich, Schmahl, W., Schweizer, U., Jakupoglu, Cemile, Brielmeier, Markus, Heike Beck, Schmahl, Wolfgang W., Marcus Conrad, Conrad, M., Jörg Schmidt, Brielmeier, M., Förster, Heidi, Conrad, Marcus, Förster, H., Beck, H., Wolfgang Schmahl, Beck, Heike, Jakupoglu, C., Cemile Jakupoglu, Soerensen, J., Heidi Förster, Ulrich Schweizer, Schmidt, J.   +26 more
core   +2 more sources

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Consensus guidelines for the management of posterior fossa tumour for low- and middle-income countries

Journal of the Pakistan Medical Association
The posterior fossa is a limited compartment therefore lesions compressing its structures can result in devastating outcomes. It can cause significant neurological deficit due to mass effect on critical structures and hydrocephalus. Due to the nature of
Hafiza Fatima Aziz, Mohammad Hamza Bajwa, Naureen Mushtaq, Saqib Kamran Bakhshi, Kaynat Siddiqui, Saad Akhtar Khan, Rabeet Tariq, Muhammad Shakir, Mehar Masroor, Fatima Suleman, Pakistan Brain Tumour Consortium: (Authors list at the end of the supplement), Syed Ather Enam   +11 more
doaj   +1 more source

Telovelar approach versus transvermian approach in management of fourth ventricular tumors

Egyptian Journal of Neurosurgery, 2019
Background The relationships of the fourth ventricle to the cerebellar surfaces and the fissures through which the fourth ventricle is approached surgically are among the most complex in the brain.
Khaled Saeed Ebrahim, Ahmed Faisal Toubar   +1 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Aggressive CNS Embryonal Tumours: A Series of Three Cases

Journal of Clinical and Diagnostic Research
Central Nervous System (CNS) embryonal tumours represent a heterogeneous group of aggressive paediatric neoplasms with variable clinical presentations, histopathological features, and outcomes.
Shima Kannadas, Rahila Musthafa
doaj   +1 more source

Cystic Lesions of the Pancreas [PDF]

, 2014
With the increasing use of abdominal imaging, cystic lesions of the pancreas are being more frequently detected. These lesions may carry a significant premalignant potential.
Azzopardi, Neville
core  

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Rare neoplasms

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
Valentina Ciaravino, CIARAVINO, VALENTINA, Roberto Malagò, MALAGO', Roberto, Roberto Pozzi Mucelli, Capelli, Paola, Paola Capelli, DE ROBERTIS LOMBARDI, Riccardo, PEDICA, Federica, Riccardo De Robertis, Federica Pedica, POZZI MUCELLI, Roberto   +11 more
core   +1 more source

Paraneoplastic cerebellar degeneration associated with lymphoepithelial carcinoma of the tonsil [PDF]

, 2013
Background: Paraneoplastic cerebellar degeneration (PCD) is a classical tumor-associated, immune-mediated disease typically associated with gynecological malignancies, small-cell lung-cancer or lymphoma.
Helmuth Steinmetz, Steinmetz, Helmuth, Henke, Christian, Christian Henke, Sylvia Hartmann, Marcus Middendorp, Hartmann, Sylvia, Johannes Rieger, Ulf Ziemann, Rieger, Johannes, Middendorp, Marcus, Ziemann, Ulf   +11 more
core   +2 more sources