Results 71 to 80 of about 182,686 (297)
Advanced Science, EarlyView.Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin +7 more
wiley +1 more source
Malignant Transformation of Grade II Ependymoma in a 2-Year-Old Child: Case Report
Journal of Neurological Surgery Reports, 2015 Ependymomas are central nervous system neoplasms that account for a third of all posterior fossa tumors in children. The most common location for infratentorial ependymoma is within the fourth ventricle.
Şule Sarıkafa +3 more
doaj +1 more source
Advanced Science, EarlyView.Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng +15 more
wiley +1 more source
Advanced Science, EarlyView.HIV preferentially infects microglia, activating IL‐17A‐driven IFN‐γ/STAT1, CEBPB, and NF‐κB signaling that converges with cGAS‐STING and Notch–NEURL1 pathways, promoting neuroinflammation, mitochondrial dysfunction, and synaptic impairment. cART suppresses viral replication, attenuates inflammatory signaling, and at least partially restores ...
Karthick Chennakesavan +7 more
wiley +1 more source
Frontiers in ImmunologyTumefactive demyelination is a rare phenotypic subtype of myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) and poses significant diagnostic challenges due to substantial clinical and radiological overlap with intracranial ...
XiaoDan Zheng +3 more
doaj +1 more source
The Relationships Between The Superior Cerebellar Artery and Trochlear Nerve
, 2009 Trochlear nerve palsy has been based on head trauma, various inflammatory and infectious disorders, vascular diseases and neoplasms. In many cases cause of the nerve palsy unclear.
Eray Tüccar +3 more
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Advanced Science, EarlyView.GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko +5 more
wiley +1 more source
An exploration of the lived experience of progressive cerebellar Ataxia: An interpretative phenomenological analysis [PDF]
, 2012 This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel UniversityBackground and Purpose: Progressive cerebellar ataxia is a rare neurological condition characterised by uncoordinated movement, and impaired speech ...
Cassidy, Elizabeth Emma
core +5 more sources
Anti-Yo–associated paraneoplastic cerebellar degeneration revealing appendiceal adenocarcinoma: a case report with complete neurological recovery [PDF]
Journal of Neurocritical CareBackground Paraneoplastic cerebellar degeneration (PCD) is a rare immune-mediated disorder often linked to gynecologic or breast tumors, with anti-Yo antibodies being a key marker.
Ümitcan Ateş
doaj +1 more source
Role of Cerebellar Interpositus Nucleus in the Genesis and Control of Reflex and Conditioned Eyelid Responses [PDF]
, 2004 The role of cerebellar circuits in the acquisition of new motor abilities is still a matter of intensive debate. To establish the contribution of posterior interpositus nucleus (PIN) to the performance and/or acquisition of reflex and classically ...
Jimenez-Diaz, L +3 more
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