Results 51 to 60 of about 471,049 (371)

In Vitro Antioxidant Activity of Purple Grape Juice (Vitis Labrusca) against Temozolamide Treatment in Rat Brains

Beverages, 2018
Considering that grape juice has high levels of phenolic compounds that produce beneficial physiological effects, important for the maintenance of redox balance, the aim of this study was to evaluate the in vitro neuroprotective effect of purple grape ...
Tatiane Gabardo, Marina Rocha Frusciante, Jessica Pereira Marinho, Manuela dos Santos, Ana Lúcia Abujamra, Caroline Dani, Cláudia Funchal   +6 more
doaj   +1 more source

Contribution of the Cerebellum and the Basal Ganglia to Language Production: Speech, Word Fluency, and Sentence Construction—Evidence from Pathology

Cerebellum, 2020
Evidence reported in recent decades increasingly confirms that both the cerebellum and the basal ganglia, which are primarily involved in movement control, also have a significant role in a vast range of cognitive and affective functions.
M. Silveri
semanticscholar   +1 more source

Association between a longer duration of illness, age and lower frontal lobe grey matter volume in schizophrenia [PDF]

, 2008
The frontal lobe has an extended maturation period and may be vulnerable to the long-term effects of schizophrenia. We tested this hypothesis by studying the relationship between duration of illness (DoI), grey matter (GM) and cerebro-spinal fluid (CSF ...
Abe, Alexander, Ananth, Andreasen, Andrew Simmons, Antonova, Ashburner, Ashburner, Baare, Bachmann, Bartzokis, Bartzokis, Burgess, Callicott, Chein, Chen, Chen, Cornblatt, Cuesta, Desmond, Dominic Fannon, Elizabeth Kuipers, Ettinger, Fannon, Fannon, First, First, Gold, Goldman-Rakic, Goldman-Rakic, Gur, Heaton, Hietala, Kay, Kukolja, Lopez-Garcia, Madden, Mathalon, Matthews, Michael A. Cooke, Milner, Molina, Molina, Molina, Northcutt, Pfefferbaum, Picard, Preethi Premkumar, Premkumar, Premkumar, Sapara, Scully, Seidman, Selemon, Shapiro, Shenton, Sim, Steen, Stroop, Sullivan, Sumich, van Haren, Veena Kumari, Velakoulis, Walter, Wassink, Wechesler, Wechsler   +67 more
core   +1 more source

Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: accumulation in Purkinje cells of the cerebellum [PDF]

, 2005
Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating four specific E-type prostanoid receptors (EP1, EP2, EP3
Akundi, Ravi S., Candelario-Jalil, Eduardo, Fiebich, Bernd L., Hull, Michael, Ridelis, Ingrid, Slawik, Helen, Waschbisch, Anne   +6 more
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Cerebellar deep brain stimulation rescues Purkinje cell mitochondrial density in a genetic mouse model of cerebellar ataxia

Brain Research Bulletin
Deep brain stimulation (DBS) improves motor function in a growing list of movement diseases including Parkinson’s disease, dystonia, and tremor. There is evidence that DBS may also be effective in ataxia.
Lauren N. Miterko-Myers, Lauren E. Peacoe, Lita Duraine, Zhongyuan Zuo, Roy V. Sillitoe   +4 more
doaj   +1 more source

Structural atrophy and functional dysconnectivity patterns in the cerebellum relate to cerebral networks in svMCI

Frontiers in Neuroscience, 2023
Subcortical vascular mild cognitive impairment (svMCI) is associated with structural and functional changes in the cerebral cortex affecting major brain networks.
Alaka Acharya, Peng Ren, Liye Yi, Weiming Tian, Xia Liang, Xia Liang   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cerebellar Circuits for Classical Fear Conditioning

Frontiers in Cellular Neuroscience, 2022
Accumulating evidence indicates that the cerebellum is critically involved in modulating non-motor behaviors, including cognition and emotional processing.
Kyoung-Doo Hwang, Kyoung-Doo Hwang, Sang Jeong Kim, Sang Jeong Kim, Sang Jeong Kim, Sang Jeong Kim, Yong-Seok Lee, Yong-Seok Lee, Yong-Seok Lee, Yong-Seok Lee   +9 more
doaj   +1 more source

Functional gradients of the cerebellum

bioRxiv, 2018
A central principle for understanding the cerebral cortex is that macroscale anatomy reflects a functional hierarchy from primary to transmodal processing.
X. Guell, J. Schmahmann, J. Gabrieli, Satrajit S. Ghosh   +3 more
semanticscholar   +1 more source