Results 121 to 130 of about 32,043 (291)

Multiple intracranial hemorrhages in a postmenopausal female

Brain Pathology, EarlyView.
Xinhua Lu, Xinya Xu, Xiaopeng Zhang
wiley   +1 more source

Why Abeta42 Is Much More Toxic Than Abeta40 [PDF]

arXiv, 2018
Amyloid precursor with 770 amino acids dimerizes and aggregates, as do its c terminal 99 amino acids and amyloid 40,42 amino acids fragments. The titled question has been discussed extensively, and here it is addressed further using thermodynamic scaling theory to analyze mutational trends in structural factors and kinetics.
arxiv  

A Collet–Sicard syndrome due to internal carotid artery dissection associated with cerebral amyloid angiopathy–related inflammation

SAGE Open Medical Case Reports, 2018
Background: Cerebral amyloid angiopathy–related inflammation is a rare condition with approximately 100 reported cases. Its clinical manifestations are varied. We report here a novel presentation of this disease.
Vanessa Saliou, Douraied Ben Salem, Julien Ognard, Dewi Guellec, Pascale Marcorelles, François Rouhart, Fabien Zagnoli, Serge Timsit   +7 more
doaj   +1 more source

Mechanical Characterization of Amyloid Fibrils Using Coarse-Grained Normal Mode Analysis [PDF]

Advanced Functional Materials 2011, 2011
Recent experimental studies have shown that amyloid fibril formed by aggregation of {\beta} peptide exhibits excellent mechanical properties comparable to other protein materials such as actin filaments and microtubules. These excellent mechanical properties of amyloid fibrils are related to their functional role in disease expression.
arxiv  

Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes. [PDF]

, 1983
Harry V. Vinters, J. J. Gilbert
openalex   +1 more source

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease

PLoS ONE, 2018
Introduction White matter hyperintensity (WMH) volume on MRI is increased among presymptomatic individuals with autosomal dominant mutations for Alzheimer’s disease (AD).
Seonjoo Lee, M. Zimmerman, Atul Narkhede, S. E. Nasrabady, G. Tosto, Irene B. Meier, T. Benzinger, D. Marcus, A. Fagan, Nick C Fox, N. Cairns, D. Holtzman, V. Buckles, B. Ghetti, E. McDade, R. Martins, A. Saykin, C. Masters, J. Ringman, Stefan Fӧrster, P. Schofield, R. Sperling, Keith A. Johnson, J. Chhatwal, S. Salloway, S. Correia, C. Jack, M. Weiner, R. Bateman, J. Morris, R. Mayeux, A. Brickman   +31 more
semanticscholar   +1 more source

In silico prediction of functional loss of cst3 gene in hereditary cerebral amyloid angiopathy

Bangladesh Journal of Pharmacology, 2013
The computational identification of missense mutation in CST3 (CYSTATIN 3 or CYSTATIN C) gene has been done in the present study. The missense mutations in the CST3 gene will leads to hereditary cerebral amyloid angiopathy  The initiation of the analysis
Piyush Choudhary, Juhee Singh, V. Karthick, V. Shanthi, R. Rajasekaran, Karuppasamy Ramanathan   +5 more
doaj   +1 more source

Cerebral microbleeds: Association with cognitive decline and pathology build-up [PDF]

arXiv
Cerebral microbleeds, markers of brain damage from vascular and amyloid pathologies, are linked to cognitive decline in aging, but their role in Alzheimer's disease (AD) onset and progression remains unclear. This study aimed to explore whether the presence and location of lobar microbleeds are associated with amyloid-$\beta$ (A$\beta$)-PET, tau tangle
arxiv  

Cerebral amyloid angiopathy in dementia and old age. [PDF]

, 1986
Margaret M. Esiri, Gordon Wilcock
openalex   +1 more source

The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice

Journal of Neurology Neurosurgery & Psychiatry, 2017
Cerebral amyloid angiopathy (CAA) has never been more relevant. The last 5 years have seen a rapid increase in publications and research in the field, with the development of new biomarkers for the disease, thanks to advances in MRI, amyloid positron ...
G. Banerjee, R. Carare, C. Cordonnier, S. Greenberg, J. Schneider, Eric E. Smith, M. van Buchem, J. van der Grond, M. Verbeek, D. Werring   +9 more
semanticscholar   +1 more source