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Radiologic Clinics of North America, 2023
Cerebral amyloid angiopathy (CAA) is associated with deposition of amyloid proteins within the intracranial vessels. It is most frequently sporadic and risk increases with advancing age. Amyloid deposition is associated with increased risk of peripheral microhemorrhage, lobar hemorrhage, and/or repetitive subarachnoid hemorrhage.
Laszlo, Szidonya, Joshua P, Nickerson
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Cerebral amyloid angiopathy (CAA) is associated with deposition of amyloid proteins within the intracranial vessels. It is most frequently sporadic and risk increases with advancing age. Amyloid deposition is associated with increased risk of peripheral microhemorrhage, lobar hemorrhage, and/or repetitive subarachnoid hemorrhage.
Laszlo, Szidonya, Joshua P, Nickerson
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Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline [PDF]
Brain, 2022 Accumulating data suggest that cerebrovascular disease contributes to Alzheimer's disease pathophysiology and progression toward dementia. Cerebral amyloid angiopathy is a form of cerebrovascular pathology that results from the build-up of β-amyloid in ...
Kaitlin Casaletto +2 more
exaly +2 more sources
The Neuroradiology Journal, 2012
Cerebral amyloid angiopathy (CAA) is cerebrovascular amyloid deposition. It is classified into several types according to the cerebrovascular amyloid proteins involved [amyloid β-protein (Aβ), cystatin C (ACys), prion protein (APrP), transthyretin (ATTR), gelsolin (AGel), ABri/ADan, and AL]. Sporadic Aβ-type CAA is commonly found in elderly individuals
Masahito, Yamada, Hironobu, Naiki
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Cerebral amyloid angiopathy (CAA) is cerebrovascular amyloid deposition. It is classified into several types according to the cerebrovascular amyloid proteins involved [amyloid β-protein (Aβ), cystatin C (ACys), prion protein (APrP), transthyretin (ATTR), gelsolin (AGel), ABri/ADan, and AL]. Sporadic Aβ-type CAA is commonly found in elderly individuals
Masahito, Yamada, Hironobu, Naiki
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Neurology, 1985
We studied 24 patients with autopsy-proven cerebral amyloid angiopathy. Eight patients were demented or had some other medical problem and died of pneumonia or systemic disease. Sixteen patients died of intracranial hemorrhage. Amyloid was found in cortical arteries and arterioles of all patients.
G R, Cosgrove +3 more
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We studied 24 patients with autopsy-proven cerebral amyloid angiopathy. Eight patients were demented or had some other medical problem and died of pneumonia or systemic disease. Sixteen patients died of intracranial hemorrhage. Amyloid was found in cortical arteries and arterioles of all patients.
G R, Cosgrove +3 more
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Human Pathology, 1981
Cerebral amyloid angiopathy is nonspecific disease entity that has been associated with a number of neuropathologic conditions, the most prominent being dementia and cerebral hemorrhage. It occurs more commonly than is generally appreciated, with implications that may be overlooked.
C T, Vanley +3 more
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Cerebral amyloid angiopathy is nonspecific disease entity that has been associated with a number of neuropathologic conditions, the most prominent being dementia and cerebral hemorrhage. It occurs more commonly than is generally appreciated, with implications that may be overlooked.
C T, Vanley +3 more
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Neuropathology and Applied Neurobiology, 1996
The cerebral amyloid angiopathies comprise a heterogeneous group of disorders that are characterized clinically by ischaemic and/or haemorrhagic strokes, and histologically by deposition of amyloid in the wall of leptomeningeal and cerebral cortical blood vessels. On the basis of the molecular composition of the amyloid, two forms can be distinguished.
F, Coria, I, Rubio
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The cerebral amyloid angiopathies comprise a heterogeneous group of disorders that are characterized clinically by ischaemic and/or haemorrhagic strokes, and histologically by deposition of amyloid in the wall of leptomeningeal and cerebral cortical blood vessels. On the basis of the molecular composition of the amyloid, two forms can be distinguished.
F, Coria, I, Rubio
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Cerebral amyloid angiopathy in the aged
Journal of Neurology, 1987Cerebral amyloid angiopathy (CAA) was found in 57% of 123 autopsy brains removed from patients aged 59-101 years. The incidence of CAA increased with age. CAA was seen most frequently in the occipital cortex. Immunohistochemically, amyloid of CAA was positive for amyloid P component and negative for human AA protein and human prealbumin.
M, Yamada +3 more
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Ubiquitin in cerebral amyloid angiopathy
Journal of the Neurological Sciences, 1992Immunohistological findings in cerebral blood vessels of 4 cases with cerebral amyloid angiopathy (CAA) were compared with those of 4 Alzheimer's (AD) cases. A panel of antibodies against 2 neurofilament subunits (BF10 and RT97), a microtubule-associated protein (TAU) and ubiquitin were used.
F F, Cruz-Sanchez +5 more
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Nihon rinsho. Japanese journal of clinical medicine, 2007
Cerebral amyloid angiopathy is characterised by the presence of protein deposits in the wall of the cerebral vessels. Sporadic forms with deposits of Abeta peptide are the most frequent. The diagnosis of cerebral amyloid angiopathy is only certain when amyloid deposits can be visualized on cerebral tissue by biopsy, that appears in most circumstances ...
Yasuo, Harigaya, Mikio, Shoji
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Cerebral amyloid angiopathy is characterised by the presence of protein deposits in the wall of the cerebral vessels. Sporadic forms with deposits of Abeta peptide are the most frequent. The diagnosis of cerebral amyloid angiopathy is only certain when amyloid deposits can be visualized on cerebral tissue by biopsy, that appears in most circumstances ...
Yasuo, Harigaya, Mikio, Shoji
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New England Journal of Medicine, 2004
From a clinical perspective, cerebral amyloid angiopathy (CAA) can be defined as amyloid deposition in the cerebral vessels sufficient to cause symptomatic vascular dysfunction. The syndromes associated with CAA have become increasingly well recognized in clinical practice.
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From a clinical perspective, cerebral amyloid angiopathy (CAA) can be defined as amyloid deposition in the cerebral vessels sufficient to cause symptomatic vascular dysfunction. The syndromes associated with CAA have become increasingly well recognized in clinical practice.
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