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Neuropathology and Applied Neurobiology, 1996
The cerebral amyloid angiopathies comprise a heterogeneous group of disorders that are characterized clinically by ischaemic and/or haemorrhagic strokes, and histologically by deposition of amyloid in the wall of leptomeningeal and cerebral cortical blood vessels. On the basis of the molecular composition of the amyloid, two forms can be distinguished.
F, Coria, I, Rubio
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The cerebral amyloid angiopathies comprise a heterogeneous group of disorders that are characterized clinically by ischaemic and/or haemorrhagic strokes, and histologically by deposition of amyloid in the wall of leptomeningeal and cerebral cortical blood vessels. On the basis of the molecular composition of the amyloid, two forms can be distinguished.
F, Coria, I, Rubio
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New England Journal of Medicine, 2004
From a clinical perspective, cerebral amyloid angiopathy (CAA) can be defined as amyloid deposition in the cerebral vessels sufficient to cause symptomatic vascular dysfunction. The syndromes associated with CAA have become increasingly well recognized in clinical practice.
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From a clinical perspective, cerebral amyloid angiopathy (CAA) can be defined as amyloid deposition in the cerebral vessels sufficient to cause symptomatic vascular dysfunction. The syndromes associated with CAA have become increasingly well recognized in clinical practice.
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Ubiquitin in cerebral amyloid angiopathy
Journal of the Neurological Sciences, 1992Immunohistological findings in cerebral blood vessels of 4 cases with cerebral amyloid angiopathy (CAA) were compared with those of 4 Alzheimer's (AD) cases. A panel of antibodies against 2 neurofilament subunits (BF10 and RT97), a microtubule-associated protein (TAU) and ubiquitin were used.
F F, Cruz-Sanchez +5 more
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Cerebral amyloid angiopathy in the aged
Journal of Neurology, 1987Cerebral amyloid angiopathy (CAA) was found in 57% of 123 autopsy brains removed from patients aged 59-101 years. The incidence of CAA increased with age. CAA was seen most frequently in the occipital cortex. Immunohistochemically, amyloid of CAA was positive for amyloid P component and negative for human AA protein and human prealbumin.
M, Yamada +3 more
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The American Journal of Forensic Medicine and Pathology, 1996
Cerebral amyloid angiopathy (CAA) is a condition characterized by amyloid deposition in cerebral blood vessels. It occurs most frequently in association with clinical Alzheimer's disease but also occurs in some nondemented elderly people. CAA is a cause of spontaneous cerebral hemorrhage and may therefore present as a sudden unexpected death in an ...
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Cerebral amyloid angiopathy (CAA) is a condition characterized by amyloid deposition in cerebral blood vessels. It occurs most frequently in association with clinical Alzheimer's disease but also occurs in some nondemented elderly people. CAA is a cause of spontaneous cerebral hemorrhage and may therefore present as a sudden unexpected death in an ...
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Cerebral amyloid angiopathy-related hemorrhages
Neurological Sciences, 2008Cerebral amyloid angiopathy (CAA) is defined by the accumulation of amyloid in the walls of small-and medium-sized cerebral arteries. One of the most recognized complications of CAA is spontaneous, often recurrent, intracerebral hemorrhage, usually involving the cortex and/or subcortical white matter ("lobar hemorrhage").
PEZZINI, Alessandro +1 more
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Cerebral Amyloid Angiopathy in the Elderly
Journal of the American Geriatrics Society, 1981ABSTRACT: In this study an attempt was made to determine the relationship between cerebral amyloid angiopathy (AA) and other cerebrovascular lesions in the aged. The brains of 128 autopsy patients over 60 years of age were examined by both light and electron microscopy.
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Journal of Neuropathology and Experimental Neurology, 1986
Twenty-five cases with cerebral amyloid angiopathy (CAA) were studied. Senile plaques (SP) were present in all cases. In only eight cases which also displayed either SP (two cases), or both SP and Alzheimer's neurofibrillary tangles (NFT) (six cases), was there a history of dementia. In five cases, SP and NFT were observed without a history of dementia.
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Twenty-five cases with cerebral amyloid angiopathy (CAA) were studied. Senile plaques (SP) were present in all cases. In only eight cases which also displayed either SP (two cases), or both SP and Alzheimer's neurofibrillary tangles (NFT) (six cases), was there a history of dementia. In five cases, SP and NFT were observed without a history of dementia.
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Surgical considerations in cerebral amyloid angiopathy
Neurosurgery, 1991Abstract In cerebral amyloid angiopathy, the contractile elements of the leptomeningeal and cortical arteries are replaced by noncontractile amyloid beta protein. The incidence of amyloid angiopathy increases with advancing age. It is associated with Alzheimer's disease and spontaneous cerebral hemorrhage.
R, Leblanc +4 more
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Cerebral amyloid angiopathy and dementia.
Panminerva medica, 2004Cerebral amyloid angiopathy (CAA) is a fundamental part of the pathology of many disorders causing dementia and/or cerebral haemorrhage. In Alzheimer's disease (AD), CAA is due to the deposition of amyloid alpha protein (Abeta) within the adventitia and media of leptomeningeal and brain parenchymal arteries.
Tian, J., Shi, J., Mann, D. M A
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