Endothelial Mitochondrial Dysfunction in Cerebral Amyloid Angiopathy and Alzheimer’s Disease
Alzheimer’s disease (AD) is the most prevalent form of dementia. Cerebrovascular dysfunction is one of the earliest events in the pathogenesis of AD, as well as in vascular and mixed dementias. Cerebral amyloid angiopathy (CAA), the deposition of amyloid
Rebecca M Parodi-Rullán +2 more
semanticscholar +1 more source
Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation
Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li +5 more
wiley +1 more source
Advances of cerebral amyloid angiopathy and related cognitive impairment
Cerebral amyloid angiopathy (CAA) is a common cerebral small vessel disease(cSVD) in clinic. It is characterized by the deposition of amyloid β-protein (Aβ) in the cerebral vascular wall, including small and medium arteries of pia mater and cortex and ...
Zhen ZHEN, Yan⁃jun GUO
doaj +1 more source
Cortical superficial siderosis and bleeding risk in cerebral amyloid angiopathy
Objective To assess the association of cortical superficial siderosis (cSS) presence and extent with future bleeding risk in cerebral amyloid angiopathy (CAA).
A. Charidimou +3 more
semanticscholar +1 more source
Abstract INTRODUCTION Alzheimer's disease (AD) is the most common form of dementia, with approximately two‐thirds of AD patients being female. Basic and clinical research studies provide strong evidence that sex‐specific differences contribute to AD complexity.
Gefei Yu +7 more
wiley +1 more source
Association of angiitis of central nervous system, cerebral amyloid angiopathy, and Alzheimer's disease: Report of an autopsy case [PDF]
The association of angiitis of central nervous system (ACNS) with cerebral amyloid angiopathy (CAA) suggests a physiopathological relationship between these two affections. Few cases are reported in patients with Alzheimer’s disease (AD).
C. Annweiler +6 more
core +1 more source
Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy? [PDF]
Cerebral small vessel disease (SVD) is a major contributor to stroke, and a leading cause of cognitive impairment and dementia. Despite the devastating effects of cerebral SVD, the pathogenesis of cerebral SVD is still not completely understood. Moreover,
Alyson A. Miller, T. Michael De Silva
core +2 more sources
Early onset cerebral amyloid angiopathy following childhood exposure to cadaveric dura
Amyloid‐β transmission has been described in patients both with and without iatrogenic Creutzfeldt–Jakob disease; however, there is little information regarding the clinical impact of this acquired amyloid‐β pathology during life.
G. Banerjee +10 more
semanticscholar +1 more source
How does type 2 diabetes modify the risk of Alzheimer's disease?
Abstract Type 2 diabetes (T2D) and Alzheimer's disease (AD) are both increasing exponentially worldwide. T2D has also been identified as one of 14 modifiable risk factors for dementia, but the mechanism is unknown. T2D could promote dementia via vascular or AD neuropathological changes, and mechanistic hypotheses include central insulin resistance and ...
G. T. Sutherland +7 more
wiley +1 more source
Research progress of cerebral amyloid angiopathy associated with inflammation
Cerebral amyloid angiopathy associated with inflammation (CAA⁃I) is a rare subtype of cerebral amyloid angiopathy (CAA), and is increasingly recognized by neurologists. CAA⁃Iischaracterized by the pathological hallmarks of both CAA and vasculitis.
Wen⁃hao ZHANG +2 more
doaj

