Results 111 to 120 of about 46,178 (264)

Cerebrospinal Fluid β‐Amyloid and τ Levels in Patients With Iatrogenic Cerebral Amyloid Angiopathy, Sporadic Cerebral Amyloid Angiopathy, Alzheimer Disease, and Controls

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Iatrogenic cerebral amyloid angiopathy (iCAA) is a subform of cerebral amyloid angiopathy caused by exposure to amyloid β. The aim of this study was to assess cerebrospinal fluid amyloid and τ concentrations in iCAA in comparison with sporadic
Ulf Jensen‐Kondering, Nils G. Margraf, Slaven Pikija, Kinga Rak‐Frattner, Branko Malojcic, Senta Frol, Janja Pretnar‐Oblak, Patricia de la Riva, Ines Albajar Gomez, Jacopo C. DiFrancesco, Anna Bersano, Gregor Kuhlenbäumer, Benedetta Storti   +12 more
doaj   +1 more source

Amyloid Spells and High Blood Pressure: Imminent Danger

Case Reports in Neurology, 2014
We present the case of a 71-year-old male, admitted after a generalized tonic-clonic seizure, with a history of recurrent left arm and face paresthesias, associated with sulcal cortical subarachnoid hemorrhages. During the next 48 h, he remained agitated
Andre Caetano, Miguel Pinto, Sofia Calado, Miguel Viana-Baptista   +3 more
doaj   +1 more source

Synergistic effects of longitudinal amyloid and vascular changes on lobar microbleeds [PDF]

, 2016
OBJECTIVE: To determine whether amyloid and hypertensive cerebral small vessel disease (hCSVD) changes synergistically affect the progression of lobar microbleeds in patients with subcortical vascular mild cognitive impairment (svMCI).
Choe, YS, Jung, N-Y, Kim, HJ, Kim, JS, Kim, S, Kim, YJ, Kim, YJ, Kwak, K-C, Lee, J-H, Lee, JM, Lee, K-H, Moon, SH, Na, DL, Park, J-H, Seo, SW, Werring, DJ, Woo, S-Y   +16 more
core   +1 more source

Co‐pathologies and biological processes beyond amyloid‐beta and tau in people with Alzheimer's disease: Evidence from clinical cohort studies

Journal of Internal Medicine, Volume 299, Issue 6, Page 694-710, June 2026.
Abstract Alzheimer's disease (AD) is neuropathologically defined by amyloid‐beta (Aβ) plaques and tau neurofibrillary tangles. However, co‐pathologies and other pathobiological processes are involved in the pathogenesis of AD, contributing to neurodegeneration and clinical symptoms.
Daniel Ferreira, Tomasz Chmiela, Maria Eriksdotter, Clifford R. Jack Jr., Grégoria Kalpouzos, Anna Marseglia, Patrizia Mecocci, Agneta Nordberg, Dorota Religa, Eric Westman   +9 more
wiley   +1 more source

Cerebral inflammatory amyloid angiopathy: response to treatment [PDF]

Dementia & Neuropsychologia
Cerebral Amyloid Angiopathy (CAA) is a small vessel disease associated with β-amyloid (Aβ) deposition in cortical and leptomeningeal vessels. Traditionally diagnosed through invasive methods, it can now be identified via advanced imaging modalities ...
João Roberto Ribeiro Pimenta, Júlian Letícia Freitas, Maria Sheila Guimarães Rocha, Sonia Maria Dozzi Brucki   +3 more
doaj   +1 more source

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros, Laura Barbosa Grossi, Maria Letícia da Silva Campos, Israel Bem‐Hur Netto Cardoso, Antônio Lúcio Teixeira, Aline Silva de Miranda, Eliana Cristina de Brito Toscano   +6 more
wiley   +1 more source

Minocycline in Severe Cerebral Amyloid Angiopathy: A Single‐Center Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evidence from animal studies suggests that minocycline may reduce lobar intracerebral hemorrhage (ICH) recurrence in cerebral amyloid angiopathy, possibly by inhibiting perivascular extracellular matrix degradation in cerebral small vessels ...
Francesco Bax, Andrew Warren, Avia Abramovitz Fouks, Hilde van den Brink, Susanne J. van Veluw, Mariel G. Kozberg, Steven M. Greenberg   +6 more
doaj   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 1052-1059, May 2026.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source

Blood-Brain Barrier Dysfunction in Small Vessel Disease Related Intracerebral Hemorrhage

Frontiers in Neurology, 2018
Background and Purpose: Hypertensive vasculopathy and cerebral amyloid angiopathy are the two most common forms of cerebral small vessel disease.
Whitney M. Freeze, Whitney M. Freeze, Heidi I. L. Jacobs, Heidi I. L. Jacobs, Floris H. B. M. Schreuder, Robert J. van Oostenbrugge, Walter H. Backes, Frans R. Verhey, Catharina J. M. Klijn   +8 more
doaj   +1 more source

Familial multiple cavernous malformation syndrome : MR features in this uncommon but silent threat [PDF]

, 2016
Cerebral cavernous malformations (CCM) are vascular malformations in the brain and spinal cord. The familial form of cerebral cavernous malformation (FCCM) is uncommon.
Lemmerling, Marc, Mespreuve, Marc, Vanhoenacker, Filip   +2 more
core   +3 more sources