Results 111 to 120 of about 577,451 (225)

Cerebral amyloid angiopathy: one single entity?

Current Opinion in Neurology
Purpose of review Cerebral amyloid angiopathy (CAA) is a common brain disorder among the elderly and individuals with Alzheimer's disease, where accumulation of amyloid-ß can lead to intracerebral hemorrhage and dementia. This review discusses recent developments in understanding the pathophysiology and phenotypes of CAA.
Koemans, E.A., Etten, E.S. van
openaire   +3 more sources

Brains for dementia research at 18: Commitment to impact the value of human post‐mortem tissue

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract The Brains for Dementia Research (BDR) project was established to provide high quality, neuropathologically characterized post‐mortem brain tissue from a cohort of participants longitudinally assessed for outcomes that are relevant for research in relation to dementia.
Keeley J. Brookes, Nicola Barnett, Johanna S. Jackson, Emma J Kidd, Debra J. Lett, Jillian Madine, Ben Middlehurst, Laura E. Palmer, Laura Parkkinen, Andrew C. Robinson, Rebecca Sims, Lindsey Sinclair, Alexandra Stolzing, Philip Tinkler, Claire Troakes, Lauren Walker, The BDR Collaborative, Alan Thomas, Patrick G. Kehoe   +18 more
wiley   +1 more source

Minimally Invasive Hematoma Evacuation for Acute Spontaneous Supratentorial Intracerebral Hemorrhage: A Systematic Review and Meta‐Analysis With Trial Sequential Analysis

Brain and Behavior, Volume 16, Issue 10, October 2026.
Acute spontaneous supratentorial ICH is associated with high morbidity and mortality. In 12 RCTs involving > 2302 patients, we compared minimally invasive hematoma evacuation (MIS) with medical management or conventional surgical evacuation. MIS reduced all‐cause and 6‐month mortality and achieved greater hematoma volume reduction, but did not ...
Sahar Saleem, Zaryab Bacha, Khushal Khan, Khawaja Arham Jawaid, Muhammad Abbas, Shahab Iqbal, Umer Zaryab Khan, Muhammad Waqas, Saja Mohammed Taher Al‐Zamili, Humaira Obaid, Zuha Kashif, Abdullah Abdullah, Zahra Rehman, Javeria Javed, Kamil Ahmad Kamil   +14 more
wiley   +1 more source

Insights Into the Role of Platelet Factor 4 in Neurodegenerative Diseases

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This review summarizes potential functions of platelet factor 4 (PF4) in neurodegenerative diseases (NDs) and discusses its promise as both a biomarker and a therapeutic target. Further elucidation of PF4 signaling pathways may provide new insights into disease mechanisms and uncover novel opportunities for targeted interventions in NDs.
Qi Tian, Yanji Tong, Fang Yu, Xiaoming Hu   +3 more
wiley   +1 more source

Cortical superficial siderosis and bleeding risk in cerebral amyloid angiopathy: multicentre MRI cohort study

, 2022
Cortical superficial siderosis and bleeding risk in cerebral amyloid angiopathy: multicentre MRI cohort ...
D Werring (13553734), Y Vandermeeren (13445181), A Charidimou (13445172), Anna Peeters (13058832), H R Jaeger (13553824), P Laloux (13444674), J-C Baron (13553830), Z Fox (13445256)   +7 more
core  

A Collet–Sicard syndrome due to internal carotid artery dissection associated with cerebral amyloid angiopathy–related inflammation

SAGE Open Medical Case Reports, 2018
Background: Cerebral amyloid angiopathy–related inflammation is a rare condition with approximately 100 reported cases. Its clinical manifestations are varied. We report here a novel presentation of this disease.
Vanessa Saliou, Douraied Ben Salem, Julien Ognard, Dewi Guellec, Pascale Marcorelles, François Rouhart, Fabien Zagnoli, Serge Timsit   +7 more
doaj   +1 more source

Magnetic Resonance Imaging in Cerebral Small Vessel Disease‐Related Depression: From Visual Scoring to Artificial Intelligence

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Starting with MRI data acquisition, it presents the core steps and outputs of visual scoring, traditional machine learning, and deep learning along three evolving paths, and integrates them into the clinical application direction, illustrating the technological evolution from qualitative description to precise prediction.
Chaofang Lei, Jiaxu Chen, Yilong Wang
wiley   +1 more source

Cerebral amyloid angiopathy associated with inflammation: A systematic review of clinical and imaging features and outcome

, 2017
BackgroundCerebral amyloid angiopathy associated with inflammation is an increasingly recognized condition, characterized by an inflammatory response to the vascular deposits of β-amyloid within the brain that are the hallmark of cerebral amyloid ...
Andrej Corovic, Hugh S Markus, Siobhan Kelly   +2 more
core   +1 more source

DTI‐ALPS Primarily Reflects White Matter Diffusion Dispersion and Microstructural Heterogeneity in Neurodegeneration: Insights From Multi‐Modal MRI

Human Brain Mapping, Volume 47, Issue 14, October 1, 2026.
In a 100‐patient memory‐clinic cohort, DTI‐ALPS was evaluated along with diffusion and microstructural metrics. DTI‐ALPS correlated strongly with mode of anisotropy and orientation dispersion index, and moderately with T1/FLAIR ratio and diamagnetic susceptibility, indicating that DTI‐ALPS mainly reflects white‐matter diffusion complexity rather than ...
Luca Sacchi, Giovanni Farruggio, Giorgio Bocca, Tiziana Carandini, Milena De Riz, Laura Ghezzi, Manuela Pintus, Anna Pietroboni, Giacomo Boffa, Elisa Scola, Fabio Triulzi, Marco Bozzali, Daniela Galimberti, Mara Cercignani, Andrea Arighi   +14 more
wiley   +1 more source

Immune reactions associated with cerebral amyloid angiopathy

, 2010
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldBACKGROUND AND PURPOSE: Cerebral amyloid angiopathy (CAA) occasionally coexists with cerebral vasculitis.
Thorsteinsson, L, Matsushita, M, Itoh, Y, Suematsu, N, Yamada, M, Kawamura, J, Shintaku, M, Otomo, E, Jensson, O   +8 more
core