Results 21 to 30 of about 28,628 (268)

Screening for Familial APP Mutations in Sporadic Cerebral Amyloid Angiopathy [PDF]

, 2010
Background Advances in genetic technology have revealed that variation in the same gene can cause both rare familial and common sporadic forms of the same disease.
A Rovelet-Lecrux, AL Gloyn, Alessandro Biffi, Anna Plourde, B Rosner, C Nilsberth, Christoph Winkler, Claudia M. Prada, D Woo, DA Nickerson, E Bakker, EE Smith, Eric E. Smith, James Gusella, JC Cohen, JC Florez, Jonathan Rosand, JP Vonsattel, KA Knudsen, L Hendriks, L Miravalle, L Obici, M Vaxillaire, Matthew Frosch, MS Fernando, Robert Onofrio, SM Greenberg, Steven M. Greenberg, SX Zhang-Nunes, TJ Grabowski, Yiping Shen, YW Chen   +31 more
core   +14 more sources

Passive immunotherapy against Aβ in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage [PDF]

, 2004
BACKGROUND: Anti-Aβ immunotherapy in transgenic mice reduces both diffuse and compact amyloid deposits, improves memory function and clears early-stage phospho-tau aggregates.
Freeman, Melissa J, Gordon, Marcia N, Morgan, Dave, Rojiani, Amyn, Rosenthal, Arnon, Subbarao, Sangeetha, Wilcock, Donna M   +6 more
core   +3 more sources

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism [PDF]

, 2018
Table S1. Demographic and clinical features of human subjects used in this study. Figure S1. Aβ deposition in microvessels in AD patients and APPSw/0 mice. Figure S2. Biochemical analysis of Aβ42 aggregates. Figure S3.
Herz, Joachim, Holtzman, David M, Ma, Qingyi, Owens, Nelly Chuqui, Sagare, Abhay P, Verghese, Philip B, Wang, Min, Wu, Yingxi, Zhao, Zhen, Zlokovic, Berislav V   +9 more
core   +3 more sources

Cerebral amyloid angiopathy mimicking central nervous system metastases: a case report

Journal of Medical Case Reports, 2018
Background This case describes an unusual presentation of an intracranial hemorrhage first thought to be metastatic disease on computed tomography and magnetic resonance imaging. The healthcare team completed an exhaustive search for a primary malignancy
Christopher DeZorzi, Ruth Fernandez-Ruiz, Sarika Gupta, Katherine Harris   +3 more
doaj   +1 more source

Early MRI imaging and follow-up study in cerebral amyloid angiopathy

Open Medicine, 2021
To study the imaging features of leukoaraiosis (LA) and hemorrhage in cerebral amyloid angiopathy (CAA) patients.
Zhang Shan-chun, Jia Jian-jun, Zhao Heng-li, Zhou Bo, Wang Wei, Lu Xiang-hui, Wang Hao, Wang Zhen-fu, Wu Wei-ping   +8 more
doaj   +1 more source

Cerebral amyloid angiopathy-related inflammation presenting with a stroke-like episode

European Journal of Case Reports in Internal Medicine, 2023
Cerebral amyloid angiopathy (CAA) is characterised by B-amyloid deposition in the walls of small to medium sized arteries of the cerebral cortex and the leptomeninges.
Ana Rita Gaspar, Catarina Faustino, Mara Sousa, Marta Valentim   +3 more
doaj   +1 more source

Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. [PDF]

, 2015
In cognitively normal (CN) elderly individuals, white matter hyperintensities (WMH) are commonly viewed as a marker of cerebral small vessel disease (SVD).
Alzheimer’s Disease Neuroimaging Initiative, Braskie, Meredith N, Carmichael, Owen T, DeCarli, Charles, Scott, Julia A, Thompson, Paul M, Tosun, Duygu, Weiner, Michael   +7 more
core   +2 more sources

Cerebral Amyloid Angiopathy: Emerging Concepts [PDF]

Journal of Stroke, 2015
Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved.
Masahito Yamada
doaj   +1 more source

Volumetric analysis of carotid plaque components and cerebral microbleeds: a correlative study [PDF]

, 2017
PURPOSE: The purpose of this work was to explore the association between carotid plaque volume (total and the subcomponents) and cerebral microbleeds (CMBs).
Anzidei, Michele, DI MARTINO, Michele, Francone, Marco, Lucatelli, Pierleone, Montisci, Roberto, Porcu, Michele, Saba, Luca, Sanfilippo, Roberto, Suri, Jasjit S.   +8 more
core   +1 more source

Recurrent Subarachnoid Bleeding and Superficial Siderosis in a Patient with Histopathologically Proven Cerebral Amyloid Angiopathy

Case Reports in Neurology, 2011
A 68-year-old man with a history of hypertension presented with recurrent subarachnoid bleeding. Brain MRI showed superficial siderosis, and diagnostic cerebral angiograms did not show any intracranial vascular malformation or arterial aneurism.
P. Profice, F. Pilato, G. Della Marca, C. Colosimo, S. Gaudino, V. Arena, A. Pavone, V. Di Lazzaro   +7 more
doaj   +1 more source