Results 41 to 50 of about 577,451 (225)

Cerebral amyloid angiopathy presenting as a mass lesion.

, 1987
A rare clinical presentation of cerebral amyloid angiopathy is reported. Our patient presented with the clinical and radiological signs of a right frontal mass lesion suggesting a brain tumor, and a biopsy provided the diagnosis of cerebral amyloid ...
L Resch, C E Briceno, M Bernstein
core   +1 more source

Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study [PDF]

, 2021
To investigate the natural history and outcomes following treatment for spontaneous amyloid-related imaging abnormalities (ARIA)-like in cerebral amyloid angiopathy-related inflammation (CAA-ri)
Pascarella, Rosario, Masafumi Ihara, Perini, Giulia, Shima, Atsushi, Ricardo Nitrini, Roberto Marconi, Maria Sessa, Laura Antolini, Domenico Inzitari, Rosario Pascarella, Valenti, Raffaella, Gianpaolo Basso, Di Lazzaro, Vincenzo, Alessia Giossi, Charidimou, Andreas, Andreas Charidimou, Marcon, Michela, Roxana O. Carare, Andrea Arighi, Carare, Roxana, Tagliavini, Fabrizio, Elio Scarpini, and Fabrizio Piazza, Jacopo C. DiFrancesco, Mario Cirillo, Hagiwara, Yuta, Zedde, Marialuisa, Raffaella Valenti, Fabrizio Tagliavini, Berardino Orlandi, Villarejo-Galende, Alberto, Carare, Roxana O, Carlo Ferrarese, Vincenzo Di Lazzaro, Marialuisa Zedde, Sessa, Maria, Inzitari, Domenico, Arighi, Andrea, Basso, Gianpaolo, Marconi, Roberto, Nitrini, Ricardo, Cirillo, Mario, Michela Marcon, Ziliotto, Nicole, Alessandro Padovani, Alberto Villarejo-Galende, Yuta Hagiwara, Scarpini, Elio, Massimo Caulo, Francesco Perini, Piazza, Fabrizio, Cagnin, Annachiara, Caulo, Massimo, Juan Francisco Vazquez-Costa, Nicole Ziliotto, Antolini, Laura, Vázquez-Costa, Juan Francisco, Ferrarese, Carlo, Padovani, Alessandro, Ihara, Masafumi, Perini, Francesco, Atsushi Shima, DiFrancesco, Jacopo C, Annachiara Cagnin, Giossi, Alessia, Giulia Perini, Orlandi, Berardino, Ziliotto N., Caulo M., Scarpini E., Charidimou A., Marcon M., Marconi R., Carare R. O., Piazza F., Padovani A., Sessa M., Tagliavini F., Orlandi B., Arighi A., Perini F., Basso G., Giossi A., Cirillo M., Villarejo-Galende A., Cagnin A., Di Lazzaro V., Valenti R., Antolini L., Ferrarese C., Pascarella R., Nitrini R., DiFrancesco J. C., Shima A., Ihara M., Hagiwara Y., Perini G., Zedde M., Vazquez-Costa J. F., Inzitari D., Fabrizio Piazza   +100 more
core   +1 more source

Chronic Stress Exacerbates Cerebral Amyloid Angiopathy Through Promoting Neutrophil Extracellular Traps Formation

Advanced Science
Cerebral amyloid angiopathy (CAA) is the leading cause of vascular dementia among the elderly. Neuropsychiatric symptoms are commonly manifested in cerebral amyloid angiopathy patients but are usually considered as consequences of cerebral amyloid ...
Huipeng Huang, Xiaohui Deng, Yuge Wang, Shishi Shen, Shisi Wang, Mengyan Hu, Sanxin Liu, Xiaotao Su, Chunyi Li, Tiemei Li, Zhengqi Lu, Wei Cai   +11 more
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Bri1 gene-related dementias; A morphological and biochemical study. [PDF]

, 2006
Aspects of the neurodegenerative mechanism in AD remain unknown therefore studies on alternative models of cerebral amyloidosis, such as familial British dementia (FBD) and familial Danish dementia (FDD) may contribute to a better understanding of the ...
Lashley, T.
core  

Radiologically Isolated Cerebral Amyloid Angiopathy-Related Inflammation

, 2017
International audienceIn amyloid β-related angiitis of the central nervous system (also called cerebral amyloid angiopathy-related inflammation), cerebral amyloid angiopathy occurs in association with primary vasculitis of small- and medium-sized ...
Dimitri Renard, Eric Thouvenot, Renard, Dimitri, Thouvenot, Eric, Wacongne, Anne, Anne Wacongne   +5 more
core   +1 more source

Status epilepticus caused by cerebral amyloid angiopathy-related inflammation [PDF]

, 2016
This report discusses a case of nonconvulsive status epilepticus, caused by cerebral amyloid angiopathy-related inflammation. Brain biopsy demonstrated cerebral amyloid angiopathy, with clinical and radiographic features indicative of a fluctuating ...
Helgager, Jeffrey, Lee, Jong, Tolchin, Benjamin, Fantaneanu, Tadeau, Miller, Michael   +4 more
core   +1 more source

Spontaneous and Drug-Induced Amyloid-Related Imaging Abnormalities: Overlaps, Divergences, and Clinical Implications Across a Continuum Between Alzheimer’s Disease and Cerebral Amyloid Angiopathy

Biomolecules
Background: Amyloid-related imaging abnormalities (ARIA) have gained significance in the context of anti-amyloid therapies (AATs), exhibiting clinical and radiological manifestations that overlap with Cerebral Amyloid Angiopathy-related inflammation (CAA-
Marialuisa Zedde, Mattia Losa, Elena Grisafi, Davide D. Lucia, Ilaria Gandoglia, Massimo Del Sette, Matteo Pardini, Luca Roccatagliata, Rosario Pascarella, Fabrizio Piazza   +9 more
doaj   +1 more source

Cerebral amyloid angiopathy-related inflammation: current status and future implications

Chinese Medical Journal, 2021
. Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare but increasingly recognized subtype of CAA. CAA-RI consists of two subtypes: inflammatory cerebral amyloid angiopathy and amyloid β (Aβ)-related angiitis.
Juan-Juan Wu, Ming Yao, Jun Ni, Xiu-Yuan Hao   +3 more
doaj   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source