Results 51 to 60 of about 46,178 (264)

Anti-Aβ Autoantibodies in Amyloid Related Imaging Abnormalities (ARIA): Candidate Biomarker for Immunotherapy in Alzheimer’s Disease and Cerebral Amyloid Angiopathy [PDF]

, 2015
Amyloid-related imaging abnormalities (ARIA) represent the major severe side effect of amyloid-beta (Aβ) immunotherapy for Alzheimer’s disease (AD).
Fabrizio Piazza, Jacopo C. DiFrancesco, Martina Longoni   +2 more
core   +1 more source

Cerebral Amyloid Angiopathy and the Fibrinolytic System: Is Plasmin a Therapeutic Target?

Stroke, 2021
Cerebral amyloid angiopathy is a devastating cause of intracerebral hemorrhage for which there is no specific secondary stroke prevention treatment. Here we review the current literature regarding cerebral amyloid angiopathy pathophysiology and treatment,
C. Mutimer, C. Keragala, H. Markus, D. Werring, G. Cloud, R. Medcalf   +5 more
semanticscholar   +1 more source

Cerebral Amyloid Angiopathy: Emerging Concepts [PDF]

Journal of Stroke, 2015
Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved.
Masahito Yamada
doaj   +1 more source

Attenuation of choroidal tickness in patients with Alzheimer disease: evidence from an Italian prospective study [PDF]

, 2017
INTRODUCTION: To compare the 12-month choroidal thickness (CT) change between Alzheimer disease (AD) patients and normal subjects. METHODS: In this prospective, observational study, 39 patients with a diagnosis of mild to moderate AD and 39 age ...
Campanelli, A, D'Antonio, Fabrizia, DE LENA, Carlo, Gharbiya, M., Imbriano, L, Mallone, Fabiana, Marcelli, Michela, Trebbastoni, A   +7 more
core   +1 more source

A practical approach to the management of cerebral amyloid angiopathy

International Journal of Stroke, 2020
Cerebral amyloid angiopathy is a common small vessel disease in the elderly involving vascular amyloid-β deposition. Cerebral amyloid angiopathy is one of the leading causes of intracerebral hemorrhage and a significant contributor to age-related ...
M. Kozberg, V. Perosa, M. Gurol, Susanne J. van Veluw   +3 more
semanticscholar   +1 more source

Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils.

PLoS ONE, 2020
Fibrillar aggregates of amyloid-β (Aβ) are the main component of plaques lining the cerebrovasculature in cerebral amyloid angiopathy. As the predominant Aβ isoform in vascular deposits, Aβ40 is a valuable target in cerebral amyloid angiopathy research ...
Hye Yun Kim, HeeYang Lee, Jong Kook Lee, Hyunjin Vincent Kim, Key-Sun Kim, YoungSoo Kim   +5 more
doaj   +1 more source

An autopsy case of amyloid β-related angiitis with cognitive impairment, multiple infarcts and subcortical hemorrhage

Human Pathology: Case Reports, 2018
A 76-year-old female presented with cognitive impairment and multiple brain infarcts and died of massive subcortical cerebral hemorrhage. A premortem clinical diagnosis was not possible.
Takahiro Watanabe, MD, PhD, Shinichiro Ukon, MD, Takako Kihara, MD, Yoshi-Hiro Ide, MD, PhD, Shohei Matsuo, MD, Yuka Hayashi, MD, Shuhei Kasama, MD, PhD, Hiroo Yoshikawa, MD, PhD, Yuki Okano, Chiaki Uchida, Masahiro Yamamoto, Hiroyuki Hao, MD, PhD, Akio Kimura, MD, PhD, Seiichi Hirota, MD, PhD, Yoshitane Tsukamoto, MD, PhD   +14 more
doaj   +1 more source

Cerebral Amyloid Angiopathy

Journal of the American College of Cardiology, 2017
Christopher V Desimone, Jonathan Graff-Radford, Alejandro A Rabinstein   +2 more
exaly   +2 more sources

Drug-Induced Amyloid-Related Imaging Abnormalities: A Neurovascular Perspective on Risk Assessment

Pharmaceuticals
Background: Anti-amyloid therapies (AAT) are reshaping the therapeutic landscape of Alzheimer’s disease (AD), yet their implementation remains constrained by the risk of amyloid-related imaging abnormalities (ARIA).
Marialuisa Zedde, Mattia Losa, Andrea Donniaquio, Ilaria Gandoglia, Massimo Del Sette, Luca Roccatagliata, Fabrizio Piazza, Matteo Pardini, Rosario Pascarella   +8 more
doaj   +1 more source

Utilidad de las secuencias potenciadas en susceptibilidad paramagnética (SWI) para diferenciar crisis somestésicas de accidentes isquémicos transitorios en un paciente con angiopatía amiloide cerebral [PDF]

, 2011
Background. Cerebral amyloid angiopathy (CAA) is characterized by the deposit of β-amyloid on the walls of small and medium-sized arteries of the cerebral cortex and leptomeninges causing cerebral bleeding.
Garcia-de-Eulate, R. (Reyes), Gasca-Salas, C. (C.), Pastor, P. (Pau)   +2 more
core   +1 more source