Results 71 to 80 of about 46,178 (264)

Amyloid-β-related angiitis presenting as leptomeningitis

BMJ Neurology Open
Background Inflammatory cerebral amyloid angiopathy (ICAA) is an atypical presentation of cerebral amyloid angiopathy (CAA), caused by an autoimmune reaction against cerebral beta-amyloid deposits.
Raquel González, Ana Ramirez, Pablo Gómez-Porro, Beatriz De La Puente, Lorena Fernández, Beatriz Brea, Joaquin Carneado   +6 more
doaj   +1 more source

Parenchymal and vascular Aβ-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease [PDF]

, 2008
The deposition of the amyloid β-protein (Aβ) is one of the pathological hallmarks of Alzheimer's disease (AD). Aβ-deposits show the morphology of senile plaques and cerebral amyloid angiopathy (CAA). Senile plaques and vascular Aβ-deposits occur first in
Braak, Heiko, Griffin, W. Sue T., Thal, Dietmar Rudolf   +2 more
core   +1 more source

Cerebral amyloid angiopathy aggravates perivascular clearance impairment in an Alzheimer’s disease mouse model

Acta Neuropathologica Communications, 2020
Cerebral amyloid angiopathy (CAA), defined as the accumulation of amyloid-beta (Aβ) on the vascular wall, is a major pathology of Alzheimer’s disease (AD) and has been thought to be caused by the failure of Aβ clearance.
Shinheun Kim, J. Ahn, Hyunwoo Yang, Peter Lee, G. Koh, Y. Jeong   +5 more
semanticscholar   +1 more source

The Association Between Positive Amyloid-PET and Cognitive Decline Is Not Always Supportive of Alzheimer’s Disease: Suggestions from a Case Report

Journal of Alzheimer's Disease Reports
Amyloid-β deposition is the pathological hallmark of both cerebral amyloid angiopathy and Alzheimer’s disease dementia, clinical conditions that can share cognitive decline and positive Amyloid-PET scan.
Gemma Lombardi, Valentina Berti, Andrea Ginestroni, Benedetta Nacmias, Sandro Sorbi   +4 more
doaj   +1 more source

Cerebral Amyloid Angiopathy and Intracerebral Haemorrhage

Advances in Clinical Neuroscience & Rehabilitation, 2016
Cerebral amyloid angiopathy (CAA) is increasingly recognised, particularly as a cause of intracerebral haemorrhage and dementia. CAA may present to the clinical neurologist in a range of circumstances, including inpatient or outpatient general neurology (
David Werring, Gargi Banerjee
doaj   +1 more source

New Therapeutic Approaches for Alzheimer’s Disease and Cerebral Amyloid Angiopathy [PDF]

, 2014
Accumulating evidence has shown a strong relationship between Alzheimer’s disease (AD), cerebral amyloid angiopathy (CAA), and cerebrovascular disease.
Masafumi Ihara, Satoshi Saito
core   +2 more sources

Simultaneous Assessment of Intracranial Artery and Paravascular CSF Pulsation Using 3D Whole‐Brain Diffusion‐Prepared Cine bSSFP (DECAF) MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To propose a noninvasive and quantitative MRI approach to simultaneously assessing intracranial artery pulsation and paravascular cerebrospinal fluid (CSF) pulsation in the human brain. Methods We developed a 3D whole‐brain Diffusion‐prepared Cine bSSFP (DECAF) MRI technique, with improved motion‐sensitized driven‐equilibrium providing
Chang Ni, Xiangjian Hou, SeyyedKazem HashemizadehKolowri, Seong‐Eun Kim, Qiuting Wen, Nicholas A. Frost, J. Scott McNally, Chun Yuan, Xiaodong Ma   +8 more
wiley   +1 more source

Bone marrow mesenchymal stem cells protect against cerebral amyloid angiopathy by enhancing neutrophil mitocytosis

Neural Regeneration Research
Current treatments for cerebral amyloid angiopathy are mainly symptomatic and have limited efficacy, and there is a lack of targeted therapies. Mesenchymal stem cell transplantation improves cognitive and motor function in conditions such as Alzheimer’s ...
Mengyan Hu, Haotong Yi, Shisi Wang, Xinmei Kang, Yuxin Liu, Zhiruo Liu, Huipeng Huang, Qin Qin, Liling Yuan, Wei Cai, Wei Qiu, Zhengqi Lu, Sanxin Liu   +12 more
doaj   +1 more source

Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy

Journal of Alzheimer's Disease, 2020
Background: There is limited data on cerebrospinal fluid (CSF) biomarkers in sporadic amyloid-β (Aβ) cerebral amyloid angiopathy (CAA). Objective: To determine the profile of biomarkers relevant to neurodegenerative disease in the CSF of patients with ...
G. Banerjee, G. Ambler, A. Keshavan, R. Paterson, M. Foiani, J. Toombs, A. Heslegrave, J. Dickson, F. Fraioli, A. Groves, M. Lunn, Nick C Fox, H. Zetterberg, J. Schott, D. Werring   +14 more
semanticscholar   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source