Results 71 to 80 of about 539,823 (183)

Advances of cerebral amyloid angiopathy and related cognitive impairment

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Cerebral amyloid angiopathy (CAA) is a common cerebral small vessel disease(cSVD) in clinic. It is characterized by the deposition of amyloid β-protein (Aβ) in the cerebral vascular wall, including small and medium arteries of pia mater and cortex and ...
Zhen ZHEN, Yan⁃jun GUO
doaj   +1 more source

Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy [PDF]

, 2015
Cerebral amyloid angiopathy is a common form of small-vessel disease and an important risk factor for cognitive impairment. The mechanisms linking small-vessel disease to cognitive impairment are not well understood. We hypothesized that in patients with
Gurol, M. Edip, Fotiadis, Panagiotis, Ayres, Alison M., Rosand, Jonathan, Martinez-Ramirez, Sergi, Schultz, Aaron, Schwab, Kristin, Viswanathan, Anand, Biessels, Geert Jan, Greenberg, Steven M., Reijmer, Yael D., Johnson, Keith A., Vashkevich, Anastasia, Rosas, Diana, Shoamanesh, Ashkan, Salat, David H., Leemans, Alexander   +16 more
core   +1 more source

Research progress of cerebral amyloid angiopathy associated with inflammation

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Cerebral amyloid angiopathy associated with inflammation (CAA⁃I) is a rare subtype of cerebral amyloid angiopathy (CAA), and is increasingly recognized by neurologists. CAA⁃Iischaracterized by the pathological hallmarks of both CAA and vasculitis.
Wen⁃hao ZHANG, Ran LIU, Yi⁃ning HUANG   +2 more
doaj  

An unexpected discovery of a novel potentially pathogenic APP gene variant: a case report of slowly progressive Alzheimer’s disease with prominent cerebral amyloid angiopathy

Frontiers in Neuroscience
Amyloid precursor protein (APP) plays an essential role in brain function and development. Variants in the APP gene are associated with both familial Alzheimer’s disease and cerebral amyloid angiopathy. We report a case of early onset, slowly progressive
Matyas Sykora, Matyas Sykora, Matyas Sykora, Marie Harmackova, Eva Parobkova, Eva Parobkova, Robert Rusina, Robert Rusina, Radoslav Matěj, Radoslav Matěj, Radoslav Matěj   +10 more
doaj   +1 more source

Cerebrospinal Fluid Aβ Biomarkers Predict Recurrent Hemorrhage and Identify Cerebral Amyloid Angiopathy in Patients With Lobar Hemorrhage

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Recurrent hemorrhage represents a significant risk for patients with lobar hemorrhage and underlying cerebral amyloid angiopathy. However, it remains unknown, whether cerebrospinal fluid biomarkers of β‐amyloid (Aβ) retention, predict ...
Philipp Arndt, Malte Pfister, Frank Schreiber, Valentina Perosa, Hendrik Mattern, Jose Bernal, Berkant Bay, Marc Dörner, Marwa Al‐Dubai, Vanessa Swiatek, Belal Neyazi, Erol Sandalcioglu, Cornelia Garz, Sven G. Meuth, Michael Goertler, Stefan Vielhaber, Katja Neumann, Stefanie Schreiber   +17 more
doaj   +1 more source

Stroke caused by cerebral amyloid angiopathy: a case of difficult diagnosis [PDF]

Dementia & Neuropsychologia
. Cerebral amyloid angiopathy is a common cause of intracerebral hemorrhage, most often occurring in older adults and in patients with dementia. One of its main differential diagnoses is hypertensive intracerebral hemorrhage.
Rocío Campos Gamarra, Carla Villanueva Colina, Jimmy Palacios-García   +2 more
doaj   +1 more source

A case of cerebral amyloid angiopathy associated with cerebral venous thrombosis [PDF]

, 2017
Cerebral amyloid angiopathy is a clinical picture which is commonly seen in elderly and progressing with the deposition of amyloid in the cerebral arteries without systemic amyloidosis.
Ercan, Karabekir, Okundu, Selvi, Komurcu, Hatice Ferhan, Anlar, Omer   +3 more
core  

Immune Reactions Associated With Cerebral Amyloid Angiopathy

, 1996
Background and Purpose Cerebral amyloid angiopathy (CAA) occasionally coexists with cerebral vasculitis. An immune system may influence deposition or degradation of the amyloid in cerebral blood vessels. The purpose of this study
Masayuki Shintaku, Leifur Thorsteinsson, Eiichi Otomo, Naomi Suematsu, Masahito Yamada, Masaaki Matsushita, Yoshinori Itoh, Ólafur Jensson, Junichiro Kawamura   +8 more
core   +1 more source

Amyloid-related imaging abnormalities (ARIA) in Alzheimer’s disease: from pathophysiology to individualized risk assessment

Alzheimer’s Research & Therapy
Monoclonal antibodies targeting amyloid-β are the first approved disease-modifying treatment for Alzheimer’s disease. While amyloid-targeting therapies mitigate the progression of cognitive decline in early-stage Alzheimer’s disease, they are associated ...
Jonathan Merkel, Robert Perneczky, Frank Jessen, Lutz Frölich, Olav Jansen, Sönke Peters, Daniela Berg, Jörg B. Schulz, Thorsten Bartsch   +8 more
doaj   +1 more source

Cerebral amyloid angiopathy in dementia and old age.

, 1986
A necropsy study of 159 elderly patients drawn mainly from a prospectively assessed geriatric hospital population was carried out to investigate the relationship of cerebral amyloid angiopathy to Alzheimer's disease, other CNS disease and ageing.
Wilcock, GK, Wilcock, Gordon, Esiri, MM
core   +1 more source