Results 31 to 40 of about 539,823 (183)

Cerebral amyloid angiopathy: A case report [PDF]

, 2018
Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the accumulation of cerebral β amyloid (Aβ) in the media and intima of leptomeningeal and cortical vessels of the brain.
Saini, Bharti
core   +1 more source

Recurrent Subarachnoid Bleeding and Superficial Siderosis in a Patient with Histopathologically Proven Cerebral Amyloid Angiopathy

Case Reports in Neurology, 2011
A 68-year-old man with a history of hypertension presented with recurrent subarachnoid bleeding. Brain MRI showed superficial siderosis, and diagnostic cerebral angiograms did not show any intracranial vascular malformation or arterial aneurism.
P. Profice, F. Pilato, G. Della Marca, C. Colosimo, S. Gaudino, V. Arena, A. Pavone, V. Di Lazzaro   +7 more
doaj   +1 more source

Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils.

PLoS ONE, 2020
Fibrillar aggregates of amyloid-β (Aβ) are the main component of plaques lining the cerebrovasculature in cerebral amyloid angiopathy. As the predominant Aβ isoform in vascular deposits, Aβ40 is a valuable target in cerebral amyloid angiopathy research ...
Hye Yun Kim, HeeYang Lee, Jong Kook Lee, Hyunjin Vincent Kim, Key-Sun Kim, YoungSoo Kim   +5 more
doaj   +1 more source

Cerebral Amyloid Angiopathy: Emerging Concepts [PDF]

Journal of Stroke, 2015
Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved.
Masahito Yamada
doaj   +1 more source

Drug-Induced Amyloid-Related Imaging Abnormalities: A Neurovascular Perspective on Risk Assessment

Pharmaceuticals
Background: Anti-amyloid therapies (AAT) are reshaping the therapeutic landscape of Alzheimer’s disease (AD), yet their implementation remains constrained by the risk of amyloid-related imaging abnormalities (ARIA).
Marialuisa Zedde, Mattia Losa, Andrea Donniaquio, Ilaria Gandoglia, Massimo Del Sette, Luca Roccatagliata, Fabrizio Piazza, Matteo Pardini, Rosario Pascarella   +8 more
doaj   +1 more source

An autopsy case of amyloid β-related angiitis with cognitive impairment, multiple infarcts and subcortical hemorrhage

Human Pathology: Case Reports, 2018
A 76-year-old female presented with cognitive impairment and multiple brain infarcts and died of massive subcortical cerebral hemorrhage. A premortem clinical diagnosis was not possible.
Takahiro Watanabe, MD, PhD, Shinichiro Ukon, MD, Takako Kihara, MD, Yoshi-Hiro Ide, MD, PhD, Shohei Matsuo, MD, Yuka Hayashi, MD, Shuhei Kasama, MD, PhD, Hiroo Yoshikawa, MD, PhD, Yuki Okano, Chiaki Uchida, Masahiro Yamamoto, Hiroyuki Hao, MD, PhD, Akio Kimura, MD, PhD, Seiichi Hirota, MD, PhD, Yoshitane Tsukamoto, MD, PhD   +14 more
doaj   +1 more source

Cerebral Amyloid Angiopathy in East and West

, 2010
Cerebral amyloid angiopathy, a vasculopathy characterised by the deposition of amyloid fibrils in the arteries and arterioles in the cerebral cortex and meninges, has been reported to be associated with intracerebral haemorrhage and cognitive impairment
Yu-Wei Chen, Eric E. Smith, Ming-Jen Lee
core   +2 more sources

Chronic Stress Exacerbates Cerebral Amyloid Angiopathy Through Promoting Neutrophil Extracellular Traps Formation

Advanced Science
Cerebral amyloid angiopathy (CAA) is the leading cause of vascular dementia among the elderly. Neuropsychiatric symptoms are commonly manifested in cerebral amyloid angiopathy patients but are usually considered as consequences of cerebral amyloid ...
Huipeng Huang, Xiaohui Deng, Yuge Wang, Shishi Shen, Shisi Wang, Mengyan Hu, Sanxin Liu, Xiaotao Su, Chunyi Li, Tiemei Li, Zhengqi Lu, Wei Cai   +11 more
doaj   +1 more source

Spontaneous and Drug-Induced Amyloid-Related Imaging Abnormalities: Overlaps, Divergences, and Clinical Implications Across a Continuum Between Alzheimer’s Disease and Cerebral Amyloid Angiopathy

Biomolecules
Background: Amyloid-related imaging abnormalities (ARIA) have gained significance in the context of anti-amyloid therapies (AATs), exhibiting clinical and radiological manifestations that overlap with Cerebral Amyloid Angiopathy-related inflammation (CAA-
Marialuisa Zedde, Mattia Losa, Elena Grisafi, Davide D. Lucia, Ilaria Gandoglia, Massimo Del Sette, Matteo Pardini, Luca Roccatagliata, Rosario Pascarella, Fabrizio Piazza   +9 more
doaj   +1 more source

Bri1 gene-related dementias; A morphological and biochemical study. [PDF]

, 2006
Aspects of the neurodegenerative mechanism in AD remain unknown therefore studies on alternative models of cerebral amyloidosis, such as familial British dementia (FBD) and familial Danish dementia (FDD) may contribute to a better understanding of the ...
Lashley, T.
core