Results 21 to 30 of about 46,178 (264)

Iatrogenic cerebral amyloid angiopathy: an emerging clinical phenomenon

Journal of Neurology Neurosurgery & Psychiatry, 2022
In the last 6 years, following the first pathological description of presumed amyloid-beta (Aβ) transmission in humans (in 2015) and subsequent experimental confirmation (in 2018), clinical cases of iatrogenic cerebral amyloid angiopathy (CAA)—attributed
G. Banerjee, K. Samra, M. Adams, Z. Jaunmuktane, A. Parry-Jones, J. Grieve, A. Toma, S. Farmer, R. Sylvester, H. Houlden, P. Rudge, S. Mead, S. Brandner, J. Schott, J. Collinge, D. Werring   +15 more
semanticscholar   +1 more source

Cerebrospinal fluid biomarkers for cerebral amyloid angiopathy

Brain Communications, 2023
Integrating cerebrospinal fluid-biomarkers into diagnostic workup of patients with sporadic cerebral amyloid angiopathy may support early and correct identification.
J. Sembill, Christoph Lusse, M. Linnerbauer, M. Sprügel, Anne Mrochen, Michael Knott, T. Engelhorn, M. Schmidt, A. Doerfler, T. Oberstein, J. Maler, J. Kornhuber, P. Lewczuk, Veit Rothhammer, S. Schwab, J. Kuramatsu   +15 more
semanticscholar   +1 more source

Prevalence of cerebral amyloid angiopathy: A systematic review and meta‐analysis

Alzheimer's & Dementia, 2021
Reported prevalence estimates of sporadic cerebral amyloid angiopathy (CAA) vary widely. CAA is associated with cognitive dysfunction and intracerebral hemorrhage, and linked to immunotherapy‐related side‐effects in Alzheimer's disease (AD).
Lieke Jäkel, Anna M. de Kort, C. Klijn, Floris H. B. M. Schreuder, M. Verbeek   +4 more
semanticscholar   +1 more source

Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries

Nature Aging, 2022
Cerebral amyloid angiopathy (CAA) is a common disease in older adults that contributes to dementia1–3. In CAA, amyloid beta (Aβ) is deposited along either capillaries (type 1) or vessel walls (type 2)4, with the underlying pathophysiology incompletely ...
Xinan Chen, Xiaodan Liu, Sunil Koundal, Rena Elkin, Xiaoyue Zhu, Brittany Monte, Feng Xu, Feng Dai, M. Pedram, Hedok Lee, J. Kipnis, A. Tannenbaum, W. V. Van Nostrand, H. Benveniste   +13 more
semanticscholar   +1 more source

Cerebral Amyloid Angiopathy with Lobar Haemorrhages and CAA-Related Inflammation in an Indian Family

Cerebrovascular Diseases Extra, 2022
Introduction: Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral haemorrhage. Sporadic CAA is far more common than hereditary CAA (h-CAA). Familial CAA has not yet been described from India.
Boby Varkey Maramattom
doaj   +1 more source

Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy–Related Inflammation

Neurology, 2021
Background and Objectives The goal of this work was to investigate the natural history and outcomes after treatment for spontaneous amyloid-related imaging abnormalities (ARIA)-like in cerebral amyloid angiopathy–related inflammation (CAA-ri).
L. Antolini, J. DiFrancesco, M. Zedde, G. Basso, A. Arighi, Atsushi Shima, A. Cagnin, M. Caulo, Roxana O. Carare, A. Charidimou, M. Cirillo, V. Di Lazzaro, C. Ferrarese, A. Giossi, D. Inzitari, M. Marcon, R. Marconi, M. Ihara, R. Nitrini, B. Orlandi, A. Padovani, R. Pascarella, F. Perini, G. Perini, M. Sessa, E. Scarpini, F. Tagliavini, R. Valenti, J. Vázquez-Costa, A. Villarejo-Galende, Yuta Hagiwara, Nicole Ziliotto, F. Piazza   +32 more
semanticscholar   +1 more source

10-Year Follow-Up of a Patient with Cerebral Amyloid Angiopathy

Case Reports in Neurology, 2020
We report the case of long-term follow-up of brain magnetic imaging of cerebral amyloid angiopathy. Cerebral amyloid angiopathy is often considered a major cause of spontaneous intracerebral hemorrhage in the elderly.
Min Kyoung Kang, Byung-Woo Yoon
doaj   +1 more source

Cerebral amyloid angiopathy in the elderly [PDF]

Annals of Neurology, 2011
AbstractCerebral amyloid angiopathy (CAA) results from deposition of β‐amyloid in the media and adventitia of small arteries and capillaries of the leptomeninges and cerebral cortex and is a major cause of lobar intracerebral hemorrhage and cognitive impairment in the elderly.
Anand, Viswanathan, Steven M, Greenberg
openaire   +2 more sources

APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function

Science Translational Medicine, 2021
Targeting APOE using an anti-APOE antibody ameliorates amyloid pathology while protecting cerebrovascular integrity and function. Controlling amyloid in brain and vasculature The genetic variant ε4 of the gene APOE (APOE4) is associated with increased ...
Monica Xiong, Hong Jiang, J. R. Serrano, E. Gonzales, Chao Wang, Maud Gratuze, Rosa Hoyle, Nga Bien-Ly, Adam P. Silverman, P. Sullivan, R. Watts, J. Ulrich, G. Zipfel, D. Holtzman   +13 more
semanticscholar   +1 more source

Cerebral Amyloid Angiopathy–Related Transient Focal Neurologic Episodes

Neurology, 2021
Transient focal neurologic episodes (TFNEs) are brief disturbances in motor, somatosensory, visual, or language functions that can occur in patients with cerebral amyloid angiopathy (CAA) and may be difficult to distinguish from TIAs or other transient ...
Eric E. Smith, A. Charidimou, C. Ayata, D. Werring, S. Greenberg   +4 more
semanticscholar   +1 more source