Results 111 to 120 of about 251,708 (339)

The influence of occlusive-stenotic lesions of the arteries of the head and neck on the methods and results of surgical treatment of ruptured arterial aneurysms

open access: yesСучасні медичні технології
Aim: to analyze the results of surgical treatment of patients with ruptured arterial aneurysms in the presence of occlusive-stenotic lesions of cerebral arteries and to evaluate the impact of combined lesions on the choice of surgical treatment method.
V. P. Komarnytskyi   +4 more
doaj   +1 more source

MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats.

open access: yesPLoS ONE, 2019
Vascular pathophysiological changes after haemorrhagic stroke, such as phenotypic modulation of the cerebral arteries and cerebral vasospasms, are associated with delayed cerebral ischemia (DCI) and poor outcome.
Simon T Christensen   +5 more
doaj   +1 more source

Introgression of Brown Norway \u3cem\u3eCYP4A\u3c/em\u3e Genes onto the Dahl Salt-Sensitive Background Restores Vascular Function in SS-5\u3csup\u3eBN\u3c/sup\u3e Consomic Rats [PDF]

open access: yes, 2013
The present study tested the hypothesis that the Dahl SS (salt-sensitive) rat has vascular dysfunction due, in part, to the up-regulation of the CYP4A/20-HETE (cytochrome P450 ω-hydroxylase 4A)/20-hydroxyeicosatetraenoic acid) system.
Falck, John R.   +3 more
core   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo   +17 more
wiley   +1 more source

Features of atherosclerosis of the cerebral arteries and pathomorphology of cerebral infarctions in patients with type 2 diabetes mellitus

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Comparison of the results of 20 autopsy cases of ischemic strokesdeveloped during atherosclerosis with 20 autopsy cases of ischemicstrokes associated with atherosclerosis in combination withtype 2 diabetes mellitus (T2DM) provided data indicating a ...
P. L. Anufriev   +4 more
doaj   +1 more source

Capsaicin-Induced Ca2+ Influx and Constriction of the Middle Meningeal Artery [PDF]

open access: yes, 2014
Research in the past on transient receptor potential cation channel subfamily V member 1 (TRPV1) has been limited to mainly nervous tissue TRPV1 because of the channel’s role in pain perception.
Koide, Masayo   +5 more
core   +1 more source

Predictive Value of Neurochemical Monitoring in Large Middle Cerebral Artery Infarction [PDF]

open access: bronze, 2001
Susanne Schneweis   +7 more
openalex   +1 more source

[Thrombolysis of the middle cerebral artery]

open access: yesDer Radiologe, 2009
Intravenous thrombolysis (IVT) is the evidence-based treatment of acute ischemic stroke in the first 3 h after symptom onset (IVT 3-4.5 h: off-label use with informed consent of the patient). However, intra-arterial thrombolysis (IAT) results in higher recanalization rates of the middle cerebral artery compared to IVT.
Brekenfeld, C   +4 more
openaire   +3 more sources

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan   +12 more
wiley   +1 more source

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