Results 41 to 50 of about 1,173,497 (381)

Laser speckle contrast imaging for blood flow monitoring in predicting outcomes after cerebral ischemia-reperfusion injury in mice

BMC Neuroscience, 2022
Background In the treatment of ischemic cerebral stroke (ICS), most conventional treatments, including carotid endarterectomy and carotid artery stenting, may cause cerebral ischemia-reperfusion injury (CIRI).
Lu Yin, Tengfei Yu, Linggang Cheng, Xinyao Liu, Wei Zhang, Hongxia Zhang, Lijuan Du, Wen He   +7 more
doaj   +1 more source

Glutamate load fosters spreading depolarization under osmotic stress in brain slices

Frontiers in Cellular Neuroscience
IntroductionCerebral edema is a hallmark of lesion progression after acute ischemic stroke (AIS) and a major contributor to the evolution of spreading depolarizations (SDs). SDs trigger extracellular glutamate accumulation and excitotoxic injury, yet the
Rita Frank, Rita Frank, Stephane Marinesco, Ferenc Bari, Ákos Menyhárt, Ákos Menyhárt, Eszter Farkas, Eszter Farkas   +7 more
doaj   +1 more source

Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions

Journal of Experimental Medicine, 2022
Microglia modulate cerebral blood flow (CBF) through complex purinergic actions, which are mediated by dynamic, P2Y12 receptor-driven interactions with the vasculature. Microglial actions are partially independent of nitric oxide.
E. Császár, Nikolett Lénárt, C. Cserép, Z. Környei, Rebeka Fekete, Balázs Pósfai, D. Balázsfi, B. Hangya, A. D. Schwarcz, Eszter Szabadits, Dávid Szöllősi, K. Szigeti, D. Máthé, B. West, Katalin Sviatkó, A. Brás, Jean-Charles Mariani, A. Kliewer, Z. Lenkei, László Hricisák, Z. Benyó, M. Baranyi, B. Sperlágh, Á. Menyhárt, E. Farkas, Á. Dénes   +25 more
semanticscholar   +1 more source

The effect of end-range cervical rotation on vertebral and internal carotid arterial blood flow and cerebral inflow: a sub analysis of an MRI study [PDF]

, 2015
Introduction: Cervical spine manual therapy has been associated with a small risk of serious adverse neurovascular events, particularly to the vertebral arteries. Sustained end-range rotation is recommended clinically as a pre-manipulative screening tool;
McLeod, Lucy R., Osmotherly, Peter G., Rivett, Darren A., Thomas, Lucy C.   +3 more
core   +1 more source

Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]

, 2020
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A., Chen, Ichun Anderson, Cheng, Xiaojun, Erdener, Sefik Evren, Kılıç, Kıvılcım, Kura, Sreekanth, Lee, Blaire Ss, Postnov, Dmitry, Sunil, Smrithi, Tang, Jianbo   +9 more
core   +1 more source

Microstructured Thin Film Nitinol for a Neurovascular Flow-Diverter [PDF]

, 2016
A cerebral aneurysm occurs as a result of a weakened blood vessel, which allows blood to flow into a sac or a ballooned section. Recent advancement shows that a new device, ‘flow-diverter’, can divert blood flow away from the aneurysm sac.
Chen, Yanfei, Cheon, Seongsik, Chun, Youngjae, Howe, Connor, Lee, Yongkuk, Yeo, Woon-Hong   +5 more
core   +2 more sources

Regulation of Cerebral Blood Flow

International Journal of Vascular Medicine, 2011
The control of cerebral blood flow is complex, and only beginning to be elucidated. Studies have identified three key regulatory paradigms. The first is cerebral pressure autoregulation, which maintains a constant flow in the face of changing cerebral ...
Eric C. Peterson, Zhengfeng Wang, Gavin Britz   +2 more
doaj   +1 more source

Cerebral Blood Flow Autoregulation in Offspring From Experimentally Preeclamptic Rats and the Effect of Age

Frontiers in Physiology, 2022
Preeclampsia is a hypertensive disorder of pregnancy that causes significant, long term cardiovascular effects for both the mother and offspring. A previous study demonstrated that middle cerebral arteries in offspring from an experimental rat model of ...
Emmett E. Whitaker, Emmett E. Whitaker, Emmett E. Whitaker, Abbie C. Johnson, Sarah M. Tremble, Conor McGinn, Nicole DeLance, Marilyn J. Cipolla, Marilyn J. Cipolla, Marilyn J. Cipolla, Marilyn J. Cipolla   +10 more
doaj   +1 more source

Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus

Scientific Reports, 2016
We investigated whether type 2 diabetes (T2DM) and the presence of cognitive impairment are associated with altered cerebral blood flow (CBF). Forty-one participants with and thirty-nine without T2DM underwent 3-Tesla MRI, including a quantitative ...
J. Jansen, Frank C. G. van Bussel, Harm J. van de Haar, Matthias J. P. van Osch, P. Hofman, M. V. van Boxtel, R. V. van Oostenbrugge, M. Schram, C. Stehouwer, J. Wildberger, W. Backes   +10 more
semanticscholar   +1 more source

Cerebral blood flow autoregulation is impaired in schizophrenia [PDF]

, 2017
Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear.
al, et, Ku, Hsiao-Lun, Lane, Timothy
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