Results 61 to 70 of about 1,173,497 (381)

A simple deep breathing test reveals altered cerebral autoregulation in type 2 diabetic patients [PDF]

, 2018
Aims/hypothesis: Patients with diabetes mellitus have an increased risk of stroke and other cerebrovascular complications. The purpose of this study was to evaluate the autoregulation of cerebral blood flow in diabetic patients using a simple method that
Brown, C., Hilz, M., Marthol, H., Ziegler, D., Zikeli, U.   +4 more
core  

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

The pathogenesis of microglia in traumatic brain injury

Chinese Journal of Contemporary Neurology and Neurosurgery
The mechanism of secondary injury after tramatic brain injury (TBI) is related to inflammation reation, oxidative stress, inflammasome, and so on, and microglia are closely related to it. Microglia, as macrophage in the nervous system, participate in the
HAN Jia-liang, ZHANG Guo-bin
doaj   +1 more source

Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery. [PDF]

, 2020
Background Impaired neurological function affects 85% to 90% of cardiac arrest (CA) survivors. Pulsatile blood flow may play an important role in neurological recovery after CA.
Akbari, Yama, Bazrafkan, Afsheen, Choi, Bernard, Crouzet, Christian, Lee, Donald, Tromberg, Bruce J, Wilson, Robert H   +6 more
core   +1 more source

Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome-c-Oxidase in Traumatic Brain Injury Patients during Hypercapnoea A Broadband NIRS Study [PDF]

, 2011
Using broadband near-infrared spectroscopy (NIRS) and cerebral micro-dialysis (MD), we investigated cerebral cellular metabolism and mitochondrial redox states, following hypercapnoea in 6 patients with traumatic brain injury (TBI).
Elwell, CE, Ghosh, A, Leung, TS, Pritchard, C, Smith, M, Tachtsidis, I, Tisdall, MM   +6 more
core   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Quantitative analysis of systemic perfusion and cerebral blood flow in the modeling of aging and orthostatic hypotension

Frontiers in Physiology
Introduction: Orthostatic hypotension (OH) is common among the older population. The mechanism hypothesized by OH as a risk factor for cognitive decline and dementia is repeated transient cerebral blood flow deficiency.
Heming Cheng, Jifeng Dai, Gen Li, Dongfang Ding, Jianyun Li, Ke Zhang, Liuchuang Wei, Jie Hou   +7 more
doaj   +1 more source

ASYMMETRY OF THE BRAIN AT ADAPTATION TO HYPOXIA

Medična Informatika ta Inženerìâ, 2012
Association between cerebral blood flow and higher nervous activity in people at different stages of adaptation to the midlands was studied. Investigation were performed before, during and after a three-week stay in the mountains at an altitude of 2100 m,
V. I. Portnichenko, Yu. V. Kravchenko, O. L. Yevtushenko, О. М. Bakunovskyi, І. О. Yachnytsia, V. M. IIyin   +5 more
doaj   +1 more source

Abstract Number ‐ 54: First Fully Automated Robotic Transcranial Doppler Optimization of Cerebral Blood Flow During Cardiac Revascularization Surgery

Stroke: Vascular and Interventional Neurology, 2023
Introduction Current technologies including EEG and near infrared pulse oximetry for non‐invasive monitoring of cerebral blood flow during cardiac surgery have proven inadequate for perioperative stroke risk mitigation. Cerebral arterial flow velocity is
Christian T Devlin, Richard Morrison, Thomas G Devlin   +2 more
doaj   +1 more source

The Effect of Water Immersion during Exercise on Cerebral Blood Flow [PDF]

, 2015
Introduction: Regular exercise induces recurrent increases in cerebrovascular perfusion. In peripheral arteries, such episodic increases in perfusion are responsible for improvement in arterial function and health.
Carter, HH, Green, DJ, Ono, K, Pugh, CJA, Spence, AL, Sprung, VS, Thijssen, DHJ   +6 more
core   +1 more source