Results 61 to 70 of about 6,027 (196)
CCM3 and cerebral cavernous malformation disease [PDF]
Cerebral cavernous malformations (CCMs) are vascular lesions characterised by enlarged and irregular structure of small blood vessels in the brain, which can result in increased risk of stroke, focal neurological defects and seizures. Three different genes, CCM1/Krev/Rap1 Interacting Trapped 1, CCM2/MGC4607 and CCM3/PDCD10, are associated with the CCMs’
Kang Wang, Huanjiao Jenny Zhou, Min Wang
openaire +2 more sources
ABSTRACT Key Content Neurovascular conditions in pregnancy are rare but are associated with poor maternal and fetal outcomes. This review covers the prevalence, clinical presentation, diagnosis and management of neurovascular disorders in pregnancy. The approach to clinical assessment and investigation of pregnant women with acute or changing chronic ...
Amy Newnham +5 more
wiley +1 more source
Postzygotic mosaicism in cerebral cavernous malformation [PDF]
Background Cerebral cavernous malformations (CCMs) can cause severe neurological morbidity but our understanding of the mechanisms that drive CCM formation and growth is still incomplete. Recent experimental data suggest that dysfunctional CCM3-deficient endothelial cell clones form cavernous lesions in conjunction ...
Rath, M. +4 more
openaire +3 more sources
OBJECTIVE AND IMPORTANCE: Brainstem cavernous malformations that seem to come to a pial or ependymal surface on preoperative magnetic resonance imaging studies may, in fact, be covered by an intact layer of neural tissue.
Lawton, Michael T. +3 more
core +1 more source
Supratentorial dural-based collision of cavernoma and meningioma: a case report
Background Collision tumor is a very rare case of cerebral lesion. Approximately 50 reports of intracranial collision tumors were described in the literature.
A. V. Dubovoy +2 more
doaj +1 more source
An Insight into the microRNAs Associated with Arteriovenous and Cavernous Malformations of the Brain
Background: Brain arteriovenous malformations (BAVMs) and cerebral cavernous malformations (CCMs) are rare developmental anomalies of the intracranial vasculature, with an irregular tendency to rupture, and as of yet incompletely deciphered ...
Ioan Alexandru Florian +6 more
doaj +1 more source
Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy
Abstract INTRODUCTION Iatrogenic transmission of amyloid beta can cause cerebral amyloid angiopathy (CAA) and Alzheimer's disease (AD), but the relationship between these phenotypes is unclear. METHODS We retrospectively analyzed standardized neuropsychological and neuroimaging data from 11 patients with iatrogenic CAA (iCAA).
Larysa Panteleienko +9 more
wiley +1 more source
Increased Number of White Matter Lesions in Patients with Familial Cerebral Cavernous Malformations [PDF]
Background and purposeFamilial cerebral cavernous malformations, an autosomal dominant disorder, result in excess morbidity and mortality in affected patients. The disorder is most prevalent in the Southwest United States, where the affected families are
Kim, H +3 more
core +1 more source
Inflammation and neutrophil extracellular traps in cerebral cavernous malformation [PDF]
Cerebral Cavernous Malformation (CCM) is a brain vascular disease with various neurological symptoms. In this study, we describe the inflammatory profile in CCM and show for the first time the formation of neutrophil extracellular traps (NETs) in rodents
Sundell, Veronica +25 more
core +1 more source
Combination of multiple cerebral cavernous malformations with a falx meningioma: A clinical case
Introduction. Cerebral cavernous malformations may coexist with various disorders of the central nervous system, including brain tumors. There are few descriptions of combined cavernous malformations and meningiomas in the literature.
L. V. Shagal +4 more
doaj +1 more source

