Results 81 to 90 of about 6,027 (196)

Evaluating Strategies for the Treatment of Cerebral Cavernous Malformations

, 2010
Cerebral cavernous malformations are common vascular lesions of the central nervous system that predispose to seizures, focal neurological deficits, and potentially fatal hemorrhagic stroke.
Dean Y. Li, Kevin J. Whitehead
core   +1 more source

sj-pdf-1-jcb-10.1177_0271678X221105995 - Supplemental material for Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells

, 2022
Supplemental material, sj-pdf-1-jcb-10.1177_0271678X221105995 for Cerebral cavernous malformation development in chronic mouse models driven by dual recombinases induced gene deletion in brain endothelial cells by Xi Yang, Zifeng Dai, Caixia Gao ...
Zhiming Han (151601), Xiangjian Zheng (2938044), Bin Zhou (84959), Caixia Gao (575550), Yue Huang (285485), Zifeng Dai (12861170), Yongqiang Yin (12861173), Changbin Shi (415896), Renjing Liu (153771), Qichuan Zhuge (690521), Xi Yang (112884)   +10 more
core   +1 more source

Unusual co-occurrence of hypertrophic inferior olivary degeneration with infratentorial cavernomatosis and orbital cavernous hemangioma

Radiology Case Reports
Hypertrophic olivary degeneration (HOD) is a rare condition resulting from a lesion in the Guillain-Mollaret triangle (GMT), causing transsynaptic degeneration and hypertrophy of the inferior olivary nucleus (ION).
Jihane EL Houssni, Salma Malak Ridah, Sanae Jellal, Meryem Edderai, Hassan EN Nouali, Jamal EL Fenni, Tarik Salaheddine   +6 more
doaj   +1 more source

Unusual Presentation of Cerebral Cavernous Malformation [PDF]

Journal of Cerebrovascular and Endovascular Neurosurgery, 2015
Cerebral cavernous malformations (CMs) are vascular malformations of the central nervous system, which can be detected in the absence of any clinical symptoms. Nodules and cysts with mixed signal intensity and a peripheral hemosiderin rim are considered brain magnetic resonance imaging (MRI) findings typical of CMs.
Won-Hyung Kim, Dong-Jun Lim, Jong-Il Choi, Sung-Kon Ha, Sang-Dae Kim, Se-Hoon Kim   +5 more
openaire   +2 more sources

A Case Report and Overview of Familial Cerebral Cavernous Malformation Pathogenesis in an Adult Patient

, 2018
OBJECTIVE We present a case of a 39 year-old woman who presented with a solitary cavernous malformation hemorrhage without any other lesions, and subsequently presented several months later with a new hemorrhage from a de novo lesion.
Gooch, MD, Michael R., Manu Arul, Arul, BS, Manu K., Khanna, Omaditya, Michael Gooch, Omaditya Khanna   +5 more
core   +2 more sources

Novel KRIT1/CCM1 mutation in a patient with retinal cavernous hemangioma and cerebral cavernous malformation [PDF]

, 2010
Retinal cavernous hemangiomas are rare vascular anomalies, and can be associated with cerebral cavernous malformations (CCM). Distinct mutations have been reported in patients who have both CCMs and retinal cavernous hemangiomas. Fluorescein angiography,
Michael B. Gorin, Tara A. McCannel, Reddy, Shantan, Gorin, Michael B., Shantan Reddy, Tsui, Irena, Bradley R. Straatsma, Irena Tsui, McCannel, Tara A., Straatsma, Bradley R.   +9 more
core   +1 more source

Cerebral Cavernous Malformations

Indian Journal of Dermatology, 2021
Igor Vazquez-Osorio, Noelia García-González, Mónica Viejo-Díaz, Pablo Gonzalvo-Rodríguez, Eloy Rodríguez-Díaz   +4 more
openaire   +5 more sources

Advances in the biology of cerebral cavernous malformations

Surgical Neurology International, 2010
To provide a review of current, high-impact scientific findings pertaining to the biology of cerebral cavernous malformations (CCMs).A comprehensive literature review was conducted using PubMed to examine the current literature regarding the molecular biology and pathophysiology of CCMs.In this literature review, a comprehensive approach is taken to ...
Hauptman, Jason S., Moftakhar, Parham, Dadour, Andrew, Malkasian, Dennis, Martin, Neil A.   +4 more
openaire   +6 more sources

Developing a Randomised Efficacy PREcision medicine Platform trial design for Cavernomas: the CARE PREP study

Efficacy and Mechanism Evaluation
Background Symptomatic cerebral cavernous malformations are a rare sporadic or familial disease, which may cause haemorrhagic strokes or epileptic seizures.
Rustam Al-Shahi Salman, Kasia Adamczuk, Richard A Parker, Christopher J Weir, Roberto Latini, Helen Kim, David White, Helen Evans, Jana Bergholtz, Cornelia Lee, Carlos Casaus   +10 more
doaj   +1 more source

Unexpected distribution of KRIT1 inside the nucleus: new insight in a complex molecular pathway

European Journal of Histochemistry, 2014
KRIT1 is an 84kDa protein that lacks any relevant catalytic domains, associated with the cerebral cavernous malformation disease. We have investigated by means of ultrastructural immunocytochemistry the nuclear distribution of KRIT1 in different cell ...
S. Marzo, V. Galimberti, M. Biggiogera
doaj   +1 more source