Results 91 to 100 of about 1,916 (204)

Inherited cavernous malformations of the central nervous system: clinical and genetic features in 19 Swiss families [PDF]

, 2018
Cavernous malformations (CCMs) are benign, well-circumscribed, and mulberry-like vascular malformations that may be found in the central nervous system in up to 0.5% of the population. Cavernous malformations can be sporadic or inherited.
Andermann, F., Baumann, C., Baumgartner, R., Bonassin, F., Georgiadis, D., Graeni, C., Merlo, A., Rouleau, G., Siegel, A., Stepper, F., Sturzenegger, M., Verlaan, D.   +11 more
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Markov models for clinical decision‐making in radiation oncology: A systematic review

Journal of Medical Imaging and Radiation Oncology, Volume 68, Issue 5, Page 610-623, August 2024.
Abstract The intrinsic stochasticity of patients' response to treatment is a major consideration for clinical decision‐making in radiation therapy. Markov models are powerful tools to capture this stochasticity and render effective treatment decisions.
Lucas B McCullum, Aysenur Karagoz, Cem Dede, Raul Garcia, Fatemeh Nosrat, Mehdi Hemmati, Seyedmohammadhossein Hosseinian, Andrew J Schaefer, Clifton D Fuller, on behalf of the Rice/MD Anderson Center for Operations Research in Cancer (CORC), MD Anderson Head and Neck Cancer Symptom Working Group   +10 more
wiley   +1 more source

Endothelial cell diversity: the many facets of the crystal

The FEBS Journal, Volume 291, Issue 15, Page 3287-3302, August 2024.
Endothelial cells form the inner lining of blood vessels and play crucial roles in angiogenesis. Recent years have seen a surge in the identification of spatiotemporal molecular and functional heterogeneity of ECs. In this review, we highlight many aspects of the diversity of ECs, such as their morphological heterogeneity, the paracrine release of ...
Lorena Perez‐Gutierrez, Pin Li, Napoleone Ferrara   +2 more
wiley   +1 more source

Cavernous Malformations of the Brain: Natural History and Surgical Outcomes

Journal of the Pakistan Medical Association
Cerebral cavernous malformations (CCM) are rare, benign vascular anomalies of the central nervous system with a prevalence of 0.5–0.8%. While often discovered incidentally, they may present with seizures, headaches, focal neurological deficits, or ...
Noman Ahmed, Zanib Javed, Muhammad Shahzad Shamim   +2 more
doaj   +1 more source

Angiopoietin-2 predicts morbidity in adults with Fontan physiology. [PDF]

, 2019
Morbidity in patients with single-ventricle Fontan circulation is common and includes arrhythmias, edema, and pulmonary arteriovenous malformations (PAVM) among others. We sought to identify biomarkers that may predict such complications.
Aboulhosn, Jamil A, Boström, Kristina I, Conrad, Miles B, Guihard, Pierre J, Iruela-Arispe, M Luisa, Kim, Helen, Lluri, Gentian, Pawlikowska, Ludmila, Shirali, Aditya S   +8 more
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Stereotactic radiosurgery (SRS) for patients with brainstem cerebral cavernous malformations (CCMs): an international, multicentric study

Scientific Reports
Abstract Introduction: Brainstem cerebral cavernous malformations (CCM) are clinically more aggressive compared to superficial CCMs. Due to their location, resection can be challenging, making stereotactic radiosurgery (SRS) an attractive alternative for symptomatic patient.
Dayawansa, Sam, Dumot, Chloe, Mantziaris, Georgios, Xu, Zhiyuan, Pikis, Stylianos, Peker, Selcuk, Samanci, Yavuz, Ardor, Gokce, Nabeel, Ahmed, Reda, Wael, Tawadros, Sameh, Abdelkarim, Khaled, El-Shehaby, Amr, Eldin, Reem, Elazzazi, Ahmed, Moreno, Nuria Martínez, Álvarez, Roberto Martínez, Liscak, Roman, May, Jaromir, Mathieu, David, Tourigny, Jean-Nicolas, Tripathi, Manjul, Rajput, Akshay, Kumar, Narendra, Kaur, Rupinder, Picozzi, Piero, Franzini, Andrea, Speckter, Herwin, Hernandez, Wenceslao, Brito, Anderson, Warnick, Ronald, Alzate, Juan, Kondziolka, Douglas, Bowden, Greg, Patel, Samir, Sheehan, Jason   +35 more
openaire   +4 more sources

Creation of a database for evaluating the effect of genetic intellectual property on genetic diagnostic testing [PDF]

, 2006
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.Includes bibliographical references (leaves 33-34).In this study, we explore the impact of gene-based patents on the pricing and availability of genetic ...
Murray, Philip (Philip E.)
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FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations [PDF]

, 2016
Cerebral cavernous malformations (CCMs) are prevalent slow-flow vascular lesions which harbour the risk to develop intracranial haemorrhages, focal neurological deficits, and epileptic seizures.
Acker-Palmer, Amparo, Felbor, Ute, Fischer, Andreas, Gilissen, Christian, Kirchmaier, Bettina, Korenke, G. Christoph, Kuss, Andreas W., Neveling, Kornelia, Rath, Matthias, Schulte-Merker, Stefan, Spiegler, Stefanie, Tetzlaff, Fabian, van de Vorst, Maartje   +12 more
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Antithrombotic Therapy in Cerebral Cavernous Malformations: A Systematic Review, Meta‐Analysis, and Network Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cerebral cavernous malformations are complex vascular anomalies in the central nervous system associated with a risk of intracranial hemorrhage.
Basel Musmar, Hamza Salim, Jihad Abdelgadir, Samantha Spellicy, Nimer Adeeb, Ali Zomorodi, Allan Friedman, Issam Awad, Pascal M. Jabbour, David M. Hasan   +9 more
doaj   +1 more source

The role of MiR-23b-3p in the epileptogenesis [PDF]

, 2016
癫痫是指脑部持续存在能导致癫痫反复发作，并出现相应的神经生物学、认知、心理学，以及社会学等方面的后果的脑部疾患。目前miRNA在癫痫发生发展中的作用引起越来越多的重视。miR-23b-3p是具有多种生物学作用的miRNA，如调节神经元增殖、分化和凋亡等,参与多种神经退行性疾病的病理机制。 本研究通过腹腔注射海人酸（Kainicacid,KA）构建小鼠癫痫模型，发作达到Racine标准的4-5级作为实验组纳入标准，对照组注射相同剂量的生理盐水，并应用荧光定量PCR法对皮层和海马组织中miR-23b-3p ...
战连波
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