Results 11 to 20 of about 9,652 (216)

A Spinal Cavernous Malformation in Multiple Cerebral Cavernous Venous Malformations Syndrome

Journal of the Belgian Society of Radiology, 2023
Teaching Point: In patients with familial multiple cavernous malformation syndrome with acute focal neurological deficit, a symptomatic spinal cavernous malformation must be included in the differential diagnosis.
Guillaume Vangrinsven, Phyllis Vanwalleghem, Özkan Özsarlak   +2 more
doaj   +5 more sources

Cerebral cavernous malformations: The importance of cutaneous manifestations

Indian Journal of Dermatology, 2021
Igor Vazquez-Osorio, Noelia García-González, Mónica Viejo-Díaz, Pablo Gonzalvo-Rodríguez, Eloy Rodríguez-Díaz   +4 more
doaj   +4 more sources

Familial Cerebral Cavernous Malformations: Pathophysiology, Genetics, Biomarkers, and Treatment Perspectives. [PDF]

J Neurochem
Cerebral cavernous malformations (CCMs) are vascular lesions in the brain caused by inherited genetic mutations in the CCM1/2/3 genes that disrupt normal blood vessel function. This work demonstrates that these mutations lead to endothelial dysfunction, inflammation, and iron accumulation, which can be detected by magnetic resonance imaging (MRI) and ...
Fontes-Dantas FL, da Fontoura Galvão G, Cunha AM, de Sena Murteira Pinheiro P, Morandi V, de Souza JM.   +5 more
europepmc   +2 more sources

Cerebral cavernous malformations and epilepsy [PDF]

Neurosurgical Focus, 2006
✓Seizures and epilepsy are frequent clinical manifestations of cerebral cavernous malformations (CCMs) and represent the most common symptomatic presentation of supratentorial lesions. Clinicians often diagnose CCMs in patients after a first seizure, or in some cases after obtaining neuroimaging studies in patients suffering from chronic epilepsy ...
Issam, Awad, Pascal, Jabbour
openaire   +2 more sources

Mitral valve plasty in a patient with multiple cerebral cavernous malformations: A case report

Clinical Case Reports, 2022
Cerebral cavernous malformations (CCMs) are blood vessel malformations, often untreated if asymptomatic. However, upon cardiac surgery with cardiopulmonary bypass, cerebral edema/hemorrhage may occur.
Shigeyuki Yamashita, Kanetsugu Nagao, Toshio Doi, Shigeki Yokoyama, Akio Yamashita, Kazuaki Fukahara, Naoki Yoshimura   +6 more
doaj   +1 more source

Rigid endoscopic surgery of brainstem cavernous malformation on the cerebral aqueduct. Case report

Ukrainian Neurosurgical Journal, 2021
Cavernous angiomas (malformations) of the brain occur in 0.5% of the population. Most of them are asymptomatic, but due to their anatomical features, namely escape of blood into surrounding tissues, significant neurological symptoms can occur.
Orest I. Palamar, Andriy P. Huk, Dmytro S. Teslenko, Dmytro I. Okonskyi, Ruslan V. Aksyonov   +4 more
doaj   +1 more source

Variable expression of cerebral cavernous malformations in carriers of a premature termination codon in exon 17 of the Krit1 gene [PDF]

, 2003
Background Cerebral cavernous malformations (CCM) present as either sporadic or autosomal dominant conditions with incomplete penetrance of symptoms. Differences in genetic and environmental factors might be minimized among first-degree relatives.
Miguel Lucas, Alzenire F Costa, José M García-Moreno, Francisca Solano, Miguel A Gamero, Guillermo Izquierdo, P Labauge, S Laberge-le Couteulx, T Sahoo, M Lucas, DJ Verlaan, M Lucas, I Serebriiskii, J Zhang, T Sahoo, J Zhang, JS Zawistowski, HH Jung, HD Craig   +18 more
core   +3 more sources

Familial multiple cavernous malformation syndrome : MR features in this uncommon but silent threat [PDF]

, 2016
Cerebral cavernous malformations (CCM) are vascular malformations in the brain and spinal cord. The familial form of cerebral cavernous malformation (FCCM) is uncommon.
Lemmerling, Marc, Mespreuve, Marc, Vanhoenacker, Filip   +2 more
core   +3 more sources

Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman

Case Reports in Radiology, 2021
Cerebral cavernous malformations (CCMs) are dilated blood vessels which can develop sporadically or in familial form and are the commonest malformations of blood vessels in the spinal cord and brain.
Klenam Dzefi-Tettey, Emmanuel Kobina Mesi Edzie, Philip Narteh Gorleku, Henry Kusodzi, Abdul Raman Asemah   +4 more
doaj   +1 more source

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]

, 2015
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L, Austin, Cecilia, Awad, Issam A, De Souza, Jorge Marcondes, Gallione, Carol J, Gunel, Murat, Lee, Connie, Marchuk, Douglas A, McDonald, David A, Mikati, Abdul Ghani, Min, Wang, Rebeiz, Tania, Rorrer, Autumn, Shenkar, Robert, Shi, Changbin, Stockton, Rebecca A, Zhang, Lingjiao   +16 more
core   +2 more sources