Results 101 to 110 of about 1,609,795 (412)

Associations of Cerebrospinal Fluid Orexin‐A, Alzheimer Disease Biomarkers, and Cognitive Performance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACTObjectiveCerebrospinal fluid (CSF) orexin‐A has been suggested to be a biomarker of Alzheimer disease (AD). In both cognitively unimpaired healthy older adults and individuals with symptomatic AD, CSF orexin‐A is positively associated with CSF Aβ42, p‐tau181, and total tau (t‐tau) concentrations.
Ruijin Lu, Krish Shah, Cristina D. Toedebusch, Ashley Hess, Rachel Richardson, Emmanuel Mignot, Suzanne E. Schindler, Tammie L. S. Benzinger, Shaney Flores, Jason Hassenstab, Chengjie Xiong, John C. Morris, David M. Holtzman, Brendan P. Lucey   +13 more
wiley   +1 more source

Hippocampal Network Dynamics during Rearing Episodes

Cell Reports, 2018
Summary: Animals build a model of their surroundings on the basis of information gathered during exploration. Rearing on the hindlimbs changes the vantage point of the animal, increasing the sampled area of the environment.
Albert M. Barth, Andor Domonkos, Antonio Fernandez-Ruiz, Tamas F. Freund, Viktor Varga   +4 more
doaj  

Decrease of protein phosphatase 2A subunit B by glutamate exposure in the cerebral cortex of neonatal rats

Laboratory Animal Research, 2020
Glutamate induces neurotoxicity during brain development, causing nerve damage. Protein phosphatase 2A (PP2A) is a type of serine/threonine phosphatase that regulates various biological functions.
Ju-Bin Kang, Dong-Ju Park, Hyun-Kyoung Son, Phil-Ok Koh   +3 more
doaj   +1 more source

Change in the cortical complexity of spinocerebellar ataxia type 3 appears earlier than clinical symptoms. [PDF]

PLoS ONE, 2015
Patients with spinocerebellar ataxia type 3 (SCA3) have exhibited cerebral cortical involvement and various mental deficits in previous studies.
Tzu-Yun Wang, Chii-Wen Jao, Bing-Wen Soong, Hsiu-Mei Wu, Kuo-Kai Shyu, Po-Shan Wang, Yu-Te Wu   +6 more
doaj   +1 more source

Global and regional brain metabolic scaling and its functional consequences [PDF]

, 2007
Background: Information processing in the brain requires large amounts of metabolic energy, the spatial distribution of which is highly heterogeneous reflecting complex activity patterns in the mammalian brain.
A Ames, A Devor, A Nehlig, A Nehlig, A Noda, A Zocchi, AG De Volder, AJ Hulbert, AJ Hulbert, AL Hodgkin, B Levant, B Siesjö, BG Cragg, BL Finlay, C Dube, C Kennedy, C Koch, C Redies, C Sahlin, CA Darveau, CC Sherwood, CF Stevens, CM Bishop, CR White, D Attwell, D Purves, DA Clark, DA Pelligrino, DB Chklovskii, DB Chklovskii, DD Clarke, DFS Rolfe, E Palombo, EM Nemoto, ER Kandel, ER Weibel, G Blomqvist, GB West, GF Striedter, H Haug, H Stephan, HT Chugani, I Quelven, I Vanzetta, J Astrup, J Blin, J Karbowski, J Karbowski, Jan Karbowski, JM Pell, JR Banavar, JW Prothero, K Meguro, K Schmidt-Nielsen, K Waschke, K Zhang, KH Harrison, KU Frerichs, L Sokoloff, LC Aiello, LJ Porrino, M Erecinska, M Kleiber, M Tsacopoulos, MA Hofman, N Turner, N Turner, NR Sibson, O Nakanishi, O Sporns, P Lennie, P Maquet, PH Harvey, PJ Magistretti, PL Else, PL Madsen, R Linde, R Lydic, R Olivares, R Stingele, RA Barton, RD Martin, RD Martin, RJ Haier, RJ Schwartzman, RK Porter, RK Suarez, S Herculano-Houzel, S Passero, S Shoham, SA Sheth, SB Laughlin, SC Hempleman, SJ Herdman, T Garland, V Bouilleret, V Braitenberg, WB Levy, WB Levy, WD Heiss, Z Wang   +100 more
core   +5 more sources

Cell type specificity of neurovascular coupling in cerebral cortex

eLife, 2016
Identification of the cellular players and molecular messengers that communicate neuronal activity to the vasculature driving cerebral hemodynamics is important for (1) the basic understanding of cerebrovascular regulation and (2) interpretation of ...
Hana Uhlířová, K. Kılıç, Peifang A. Tian, Martin Thunemann, Michèle Desjardins, P. Saisan, S. Sakadžić, T. V. Ness, Céline Matéo, Qun Cheng, Kimberly L. Weldy, F. Razoux, Matthieu Vandenberghe, Jonathan A. Cremonesi, Christopher G. L. Ferri, Krystal Nizar, Vishnu B. Sridhar, Tyler C. Steed, M. Abashin, Y. Fainman, E. Masliah, S. Djurovic, O. Andreassen, G. Silva, D. Boas, D. Kleinfeld, R. Buxton, G. Einevoll, A. Dale, A. Devor   +29 more
semanticscholar   +1 more source

Essay on the Cerebral Cortex

The American Journal of Psychology, 1950
Bibliography: p. 135-150. ; Mode of access: Internet.
M. B., Gerhardt von Bonin
openaire   +2 more sources

Dual‐Phase C‐11 PiB PET Images for Detecting Tau Pathology in Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage and cognitive dysfunction in the elderly, and frequently coexists with Alzheimer's disease and tau pathology. Dual‐phase 11C‐PiB PET detects amyloid deposition and cerebral perfusion changes and may have diagnostic value for identifying tau in CAA ...
Meng‐Ting Chiang, Chia‐Ju Liu, Bo‐Ching Lee, Ruoh‐Fang Yen, Hsin‐Hsi Tsai   +4 more
wiley   +1 more source

Biomaterial-engineering and neurobiological approaches for regenerating the injured cerebral cortex

Regenerative Therapy, 2016
The cerebral cortex is responsible for higher functions of the central nervous system (CNS), such as movement, sensation, and cognition. When the cerebral cortex is severely injured, these functions are irreversibly impaired.
Itsuki Ajioka
doaj   +1 more source

Cortex Neural Network: learning with Neural Network groups [PDF]

arXiv, 2018
Neural Network has been successfully applied to many real-world problems, such as image recognition and machine translation. However, for the current architecture of neural networks, it is hard to perform complex cognitive tasks, for example, to process the image and audio inputs together. Cortex, as an important architecture in the brain, is important
arxiv