Results 101 to 110 of about 594,163 (347)

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li   +8 more
wiley   +1 more source

The Distribution of MAP-2 Phosphorylation in Cerebral Cortex of Long-Tailed Monkey Fetuses (Macaca fascicularis) in the Last Trimester of Gestation

open access: yesIndonesian Journal of Biotechnology, 2010
Memories are storage in cholinoceptive cells, the cells which are enriched with microtubule-associated protein 2 (MAP-2) that localized in the neuronal dendrite and the cell bodies.
Tri Wahyu Pangestiningsih   +2 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Aging of the Cerebral Cortex

open access: yesMcGill Journal of Medicine, 2020
Significant structural trimming of neuronal structures in the cerebral cortex has long been considered as a primary cause of various age-related cortical dysfunctions. While recent findings provided additional data to support this notion, current understanding of cortical neuronal functions in aging also revealed the ...
openaire   +4 more sources

Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a wireless and miniaturized concentric‐electrode tDCS (CE‐tDCS) system tailored for freely moving mice. The device enables focal and multi‐site cortical stimulation via a lightweight, Bluetooth‐controlled platform. By integrating local neuromodulation with real‐time behavioral analysis, the system provides a robust tool for ...
Minseok Kim   +5 more
wiley   +1 more source

Brain asymmetries related to language with emphasis on entorhinal cortex and basal forebrain [PDF]

open access: yes, 2006
Anatomical asymmetries of the human brain are important in at least four respects: 1) they can serve as potential indicators of the evolutionary foundations of language, 2) they can be used for comparative analysis of neural specializations for ...
Hof, Patrick R.   +3 more
core  

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

open access: yesAdvanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban   +5 more
wiley   +1 more source

Coordinated scaling of cortical and cerebellar numbers of neurons

open access: yesFrontiers in Neuroanatomy, 2010
While larger brains possess concertedly larger cerebral cortices and cerebella, the relative size of the cerebral cortex increases with brain size, but relative cerebellar size does not.
Suzana Herculano-Houzel
doaj   +1 more source

Structure and function of the cerebral cortex [PDF]

open access: yesCurrent Biology, 2007
The complexities of cortical circuitry are nothing short of fiendish, and the problem of integrating genetic, morphological and physiological details from diverse cortical areas and across diverse species is a worthy challenge to the burgeoning science of neuroinformatics.
openaire   +3 more sources

Upconversion Nanoparticle‐Covalent Organic Framework Core–shell Particles as Therapeutic Microrobots Trackable With Optoacoustic Imaging

open access: yesAdvanced Materials, EarlyView.
Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim   +8 more
wiley   +1 more source

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