Results 101 to 110 of about 1,638,797 (414)
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source
Dynamics of changes in the content of thyroid hormones and some neurotransmitters in brain of rats with experimental Alzheimer’s disease [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2017 Objective: Alzheimer's disease is one of the most common neurodegenerative diseases, and mechanisms of its development have been studied for many years.
Tatiana Gorbach +3 more
doaj +1 more source
THE FUNCTIONS OF THE CEREBRAL CORTEX [PDF]
The Journal of Nervous and Mental Disease, 1881 n ...
openaire +1 more source
Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]
, 2011 Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon +9 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder.
Hélène Mourre +15 more
wiley +1 more source
Hippocampal Network Dynamics during Rearing Episodes
Cell Reports, 2018 Summary: Animals build a model of their surroundings on the basis of information gathered during exploration. Rearing on the hindlimbs changes the vantage point of the animal, increasing the sampled area of the environment.
Albert M. Barth +4 more
doaj
Laboratory Animal Research, 2020 Glutamate induces neurotoxicity during brain development, causing nerve damage. Protein phosphatase 2A (PP2A) is a type of serine/threonine phosphatase that regulates various biological functions.
Ju-Bin Kang +3 more
doaj +1 more source
Thyroid hormone regulated genes in cerebral cortex development.
Journal of Endocrinology, 2017 The physiological and developmental effects of thyroid hormones are mainly due to the control of gene expression after interaction of T3 with the nuclear receptors.
J. Bernal
semanticscholar +1 more source
How the brain represents the reward value of fat in the mouth. [PDF]
, 2009 The palatability and pleasantness of the sensory properties of foods drive food selection and intake and may contribute to overeating and obesity. Oral fat texture can make food palatable and pleasant.
De Souza, Arun +3 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) can radiographically mimic multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). The disease hallmarks cortical lesion, central vein sign (CVS) and paramagnetic rim lesions identified in MS have not yet been comprehensively investigated in ...
Lei Su +19 more
wiley +1 more source