Results 11 to 20 of about 602,933 (343)

Microcolumns in the cerebral cortex [PDF]

open access: yesProceedings of the National Academy of Sciences, 2000
Neuroanatomists from Cajal on (1) have searched in the cerebral cortex for units of structural organization that transcend the laminar pattern visible even to the untutored eye in Nissl-stained preparations. Many have commented on the vertical column-like arrays of cell bodies running orthogonal to the horizontal laminae that are particularly ...
openaire   +2 more sources

Multiple conserved regulatory domains promote Fezf2 expression in the developing cerebral cortex. [PDF]

open access: yes, 2014
BackgroundThe genetic programs required for development of the cerebral cortex are under intense investigation. However, non-coding DNA elements that control the expression of developmentally important genes remain poorly defined. Here we investigate the
Chen, Bin   +8 more
core   +4 more sources

Decreased density of pyramidal cells in the cerebral cortex, and Purkinje cells in the cerebellar cortex of Sprague-Dawley rats after being exposed to filtered kretek cigarette smoke

open access: yesJournal of Biological Research, 2023
Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development,
David Tjahyadi   +5 more
doaj   +1 more source

A developmental and genetic classification for malformations of cortical development: update 2012. [PDF]

open access: yes, 2012
Malformations of cerebral cortical development include a wide range of developmental disorders that are common causes of neurodevelopmental delay and epilepsy. In addition, study of these disorders contributes greatly to the understanding of normal brain
Barkovich, A James   +4 more
core   +3 more sources

Hippocampal Network Dynamics during Rearing Episodes

open access: yesCell Reports, 2018
Summary: Animals build a model of their surroundings on the basis of information gathered during exploration. Rearing on the hindlimbs changes the vantage point of the animal, increasing the sampled area of the environment.
Albert M. Barth   +4 more
doaj   +1 more source

Subcellular organization of UBE3A in human cerebral cortex. [PDF]

open access: yes, 2018
BackgroundLoss of UBE3A causes Angelman syndrome, whereas excess UBE3A activity appears to increase the risk for autism. Despite this powerful association with neurodevelopmental disorders, there is still much to be learned about UBE3A, including its ...
Burette, Alain C   +6 more
core   +3 more sources

Correlation between brain injury and dysphagia in adult patients with stroke

open access: yesInternational Archives of Otorhinolaryngology, 2012
Introduction: In the literature, the incidence of oropharyngeal dysphagia in patients with cerebrovascular accident (AVE) ranges 20-90%. Some studies correlate the location of a stroke with dysphagia, while others do not.
Nunes, Maria Cristina de Alencar   +6 more
doaj   +3 more sources

Cellular resolution circuit mapping with temporal-focused excitation of soma-targeted channelrhodopsin

open access: yeseLife, 2016
We describe refinements in optogenetic methods for circuit mapping that enable measurements of functional synaptic connectivity with single-neuron resolution.
Christopher A Baker   +3 more
doaj   +1 more source

Sex differences in the neuronal transcriptome and synaptic mitochondrial function in the cerebral cortex of a multiple sclerosis model

open access: yesFrontiers in Neurology, 2023
IntroductionMultiple sclerosis (MS) affects the cerebral cortex, inducing cortical atrophy and neuronal and synaptic pathology. Despite the fact that women are more susceptible to getting MS, men with MS have worse disability progression.
Noriko Itoh   +4 more
doaj   +1 more source

Co-transmission of acetylcholine and GABA regulates hippocampal states

open access: yesNature Communications, 2018
Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally ...
Virág T. Takács   +10 more
doaj   +1 more source

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