Results 41 to 50 of about 1,027,636 (308)

Cortex- and striatum-derived neural stem cells produce distinct progeny in the olfactory bulb and striatum [PDF]

, 2008
Neural stem cells can be isolated from the mouse embryonic cortex but do not persist in the adult cortex. In contrast, neural stem cells from the striatal embryonic germinal zone persist in the adult subependyma.
Willaime-Morawek, S., Van der Kooy, D.
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Theoretical Investigation of NMDA Effect on the Cerebral Cortex [PDF]

, 2008
This thesis examines the dynamical behaviour of incorporating NMDA (an excitatory neurotransmitter) for the electrodynamic model of the cerebral cortex. The model used is the mean-field model developed by Steyn-Ross et al.
AL Saidi, Waleed Hamdan Khalfan
core  

Fine-grained nociceptive maps in primary somatosensory cortex [PDF]

, 2012
Topographic maps of the receptive surface are a fundamental feature of neural organization in many sensory systems. While touch is finely mapped in the cerebral cortex, it remains controversial how precise any cortical nociceptive map may be.
Longo, Matthew R., Iannetti, GD, Sereno, MI, Iannetti, G.D., Longo, MR, Haggard, P, ,, Mancini, F, Mancini, F., Haggard, P., Sereno, Martin I.   +10 more
core   +1 more source

Gyrification of the cerebral cortex requires FGF signaling in the mammalian brain

eLife, 2017
Although it has been believed that the evolution of cortical folds was a milestone, allowing for an increase in the number of neurons in the cerebral cortex, the mechanisms underlying the formation of cortical folds are largely unknown.
Naoyuki Matsumoto, Yohei Shinmyo, Yoshie Ichikawa, Hiroshi Kawasaki   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A new framework for nicotinic receptor-targeted therapeutic strategies in psychiatric and neurodegenerative disorders

Frontiers in Cellular Neuroscience
The nicotinic acetylcholine receptors (nAChRs) are key modulators of synaptic transmission and cognitive processing within the central nervous system.
Khalid Oudaha, Frédéric Causeret, Frédéric Causeret, Fani Koukouli, Fani Koukouli   +4 more
doaj   +1 more source

Radial glial dependent and independent dynamics of interneuronal migration in the developing cerebral cortex. [PDF]

PLoS ONE, 2007
Interneurons originating from the ganglionic eminence migrate tangentially into the developing cerebral wall as they navigate to their distinct positions in the cerebral cortex.
Yukako Yokota, H T Gashghaei, Christine Han, Hannah Watson, Kenneth J Campbell, E S Anton   +5 more
doaj   +1 more source

The impact of gamma-radiation on the cerebral- and cerebellar- cortex of male rats’ brain

Brain Research Bulletin, 2022
This study aims to investigate the impact of gamma-radiation on the cerebral- and cerebellar-cortex of rat’s brain. Animals were whole-body exposed to 3 Gy, every 3 days, up to 9 Gy, and sacrificed 1 h, 1, 3, 7 & 10 days post the last radiation-dose.
Fatma Rabia Algeda, Noaman Abdelatief Eltahawy, Shereen Mohamed Shedid, Helen Nicolas Saada   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source