Hypertension and acute focal cerebral ischemia. Infarction and edema after occlusion of a middle cerebral artery in cats. [PDF]
, 1979 Tõru Hayakawa +2 more
openalex +1 more source
PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity
Advanced Science, EarlyView.Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley +1 more source
Neurogenic Regulation of Cerebral Blood Flow Following Ischemia [PDF]
, 1976 Nicholas T. Zervas +3 more
openalex +1 more source
Advanced Science, EarlyView.Thrombotic ischemic stroke is a severe neurological disease of the brain that presents major challenges for effective diagnosis and treatment. Precisely engineered Ir and Mn cores within a single porphyrin framework of 4IrMn nanoparticles enable endogenous ONOO−‐ or laser‐activated switching among NIR‐CL imaging, photothermal / photodynamic therapy ...
Ziwei Wang +10 more
wiley +1 more source
Controlled trial of aspirin in cerebral ischemia. [PDF]
, 1977 William S. Fields +3 more
openalex +1 more source
The Mechanism and Potential Therapeutic Strategies of Vascular Aging
AGING MEDICINE, EarlyView.The phenotypes of vascular aging vary across different blood vessels. Endothelial dysfunction is observable in the endothelium of all vessels, while vascular structural remodeling primarily occurs in arteries. A decline in organ vascular density mainly affects arterioles, venules, and capillaries, whereas thrombosis predominantly occurs in the ...
Wan‐Zhou Wu +4 more
wiley +1 more source
Mitochondria and neuroprotection in stroke: Cationic arginine-rich peptides (CARPs) as a novel class of mitochondria-targeted neuroprotective therapeutics [PDF]
, 2018 Stroke is the second leading cause of death globally and represents a major cause of devastating long-term disability. Despite sustained efforts to develop clinically effective neuroprotective therapies, presently there is no clinically available ...
Anderton, Ryan S +4 more
core +1 more source
Prognostic Utility of the Preoperative Cachexia Index in Patients Undergoing Emergency Laparotomy
Annals of Gastroenterological Surgery, EarlyView.The preoperative cachexia index, incorporating muscle mass, nutritional status, and inflammation, predicts in‐hospital and one‐year mortality in patients undergoing emergency laparotomy. This simple index may aid in risk stratification and perioperative decision‐making in high‐risk surgical patients. ABSTRACT Aim Emergency laparotomy is associated with
Naoko Fukushima +6 more
wiley +1 more source
The Effect of Dexamethasone on the Edema of Focal Cerebral Ischemia [PDF]
, 1973 ROBERT F. DONLEY, Thoralf M. Sundt
openalex +1 more source
Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Aggregate, EarlyView.Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source